Patents by Inventor Jürg Zimmermann

Jürg Zimmermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210261711
    Abstract: Methods for using a copolymer, especially as a dispersant for solid particles, in particular as a dispersant for mineral binder compositions, where the copolymer is obtained from ionizable monomers m1 and side chain-bearing monomers m2 that are polymerized by nitroxide-mediated solution polymerization to give the copolymer, wherein the polymerization is conducted in the presence of an agent including a carboxyl group-bearing and phosphated alkoxy amine.
    Type: Application
    Filed: May 10, 2021
    Publication date: August 26, 2021
    Applicant: SIKA TECHNOLOGY AG
    Inventors: Jürg WEIDMANN, Fabia ULBER, Jörg ZIMMERMANN
  • Publication number: 20140323494
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives in which at least one nitrogen atom carries an oxygen atom to form the corresponding N-oxides, to processes for the preparation thereof, to pharmaceutical compositions comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Application
    Filed: July 14, 2014
    Publication date: October 30, 2014
    Applicant: Novartis AG
    Inventors: Klaus O. Börnsen, Peter End, Gerhard Gross, Ulrike Pfaar, Paul W. Manley, Jürg Zimmermann
  • Patent number: 8163773
    Abstract: The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula I wherein R1, R2, T, R3 and R4 are as defined in the specification.
    Type: Grant
    Filed: July 10, 2006
    Date of Patent: April 24, 2012
    Assignee: Novartis AG
    Inventors: Werner Breitenstein, Claus Erhardt, Juergen Klaus Maibaum, Nils Ostermann, Juerg Zimmermann, Keiichi Masuya, Kazuhide Konishi, Fumiaki Yokokawa, Takanori Kanazawa, Edgar Jacoby, Andreas Marzinzik, Philipp Grosche, Shimpei Kawakami
  • Publication number: 20100222362
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives derivatives in which at least one nitrogen atom carries an oxygen atom to form the corresponding N-oxides, to processes for the preparation thereof, to pharmaceutical compositions comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Application
    Filed: May 17, 2010
    Publication date: September 2, 2010
    Inventors: Klaus Olaf Börnsen, Peter End, Gerhard Gross, Ulrike Pfaar, Paul William Manley, Jürg Zimmermann
  • Publication number: 20100075966
    Abstract: The invention relates to dihydroimidazoles of formula rac-(I), wherein the radicals and symbols are as defined herein; their use as inhibitors of the interaction of the MDM2 protein with a p53-like peptide, new pharmaceutical formulations comprising said compounds, said compounds for use in the therapeutic treatment of warm-blooded animals, especially humans, their use in the treatment of proliferative diseases or for the manufacture of pharmaceutical formulations useful in the treatment of proliferative diseases that respond to modulation of the interaction of the MDM2 protein with a p53-like peptide, a pharmaceutical formulation e.g. useful in the treatment of proliferative diseases that respond to modulation of the interaction of the MDM2 protein with a p53-like peptide comprising said compound, methods of treatment comprising administration of said compounds to a warm-blooded animal, and/or processes for the manufacture of said compounds.
    Type: Application
    Filed: November 26, 2007
    Publication date: March 25, 2010
    Inventors: Sylvie Chamoin, Hans- Jorg Roth, Juerg Zimmermann, Thomas Zoller
  • Publication number: 20090233920
    Abstract: The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula I wherein R1, R2, T, R3 and R4 are as defined in the specification.
    Type: Application
    Filed: July 10, 2006
    Publication date: September 17, 2009
    Inventors: Werner Breitenstein, Claus Erhardt, Juergen Klaus Maibaum, Nils Ostermann, Juerg Zimmermann, Keiichi Masuya, Kazuhide Konishi, Fumiaki Yokokawa, Takanori Kanazawa, Edgar Jacoby, Andreas Marzinzik, Philipp Grosche, Shimpei Kawakami
  • Patent number: 7557105
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives in which at least one nitrogen atom carries an oxygen atom to form the corresponding N-oxides, to processes for the preparation thereof, to pharmaceutical compositions comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: July 7, 2009
    Assignee: Novartis AG
    Inventors: Klaus Olaf Börnsen, Peter End, Gerhard Gross, Ulrike Pfaar, Paul William Manley, Jürg Zimmermann
  • Patent number: 7544799
    Abstract: The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of formula 1, which may be used for example for tumour therapy.
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: June 9, 2009
    Assignee: Novartis AG
    Inventors: Jürg Zimmermann, Bertrand Sutter, Hans M Bürger
  • Publication number: 20080194629
    Abstract: The invention relates to 3,5-piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-piperidine compound, and/or a method of treatment comprising administering a 3,5-piperidine compound, a method for the manufacture of a 3,5-piperidine compound, and novel intermediates and partial steps for their synthesis. Especially, the 3,5-piperidine compounds have the formula I, wherein the symbols have the meanings described in the specification.
    Type: Application
    Filed: May 2, 2006
    Publication date: August 14, 2008
    Inventors: Daniel Kaspar Baeschlin, Werner Breitenstein, Claus Ehrhardt, Juergen Klaus Maibaum, Nils Ostermann, Juerg Zimmermann, Simon Rudisser, Eric Vangrevelinghe, Osamu Irie, Ichiro Umemura, Masaki Suzuki, Muneto Mogi, Takanori Kanazawa, Fumiaki Yokokawa, Atsuko Nihonyanagi
  • Publication number: 20070265292
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula I wherein the substituents are defined as indicated in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Application
    Filed: July 26, 2007
    Publication date: November 15, 2007
    Inventors: Hans Buerger, Giorgio Caravatti, Juerg Zimmermann, Paul Manley, Werner Breitenstein, Margaret Cudd
  • Publication number: 20060223818
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula I wherein the substituents are defined as indicated in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Application
    Filed: June 7, 2006
    Publication date: October 5, 2006
    Inventors: Hans Buerger, Giorgio Caravatti, Juerg Zimmermann, Paul Manley, Werner Breitenstein, Margaret Cudd
  • Patent number: 7091346
    Abstract: 2-Amino-6-anilino-purine derivatives of the formula 1 in which the symbols are as defined in claim 1 are described. These compounds inhibit p34cdc2/cyclin Bcdc13 kinase and can be used for treatment of hyperproliferative diseases, for example tumour diseases.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: August 15, 2006
    Assignee: Novartis AG
    Inventors: Jürg Zimmermann, Hans-Georg Capraro, Patricia Imbach, Pascal Furet
  • Patent number: 7081532
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula (I) wherein the substituents are defined as in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: July 25, 2006
    Assignee: Novartis AG
    Inventors: Hans M Buerger, Giorgio Caravatti, Juerg Zimmermann, Paul W Manley, Werner Breitenstein, Margaret A Cudd
  • Patent number: 6894051
    Abstract: The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]benzamide of formula 1, which may be used for example for tumor therapy.
    Type: Grant
    Filed: July 16, 1998
    Date of Patent: May 17, 2005
    Assignee: Novartis AG
    Inventors: Jürg Zimmermann, Bertrand Sutter, Hans Michael Bürger
  • Patent number: 6767906
    Abstract: This application discloses 2-amino-6-anilino-purine derivatives of the formula I in which q is 1-5, and R1 is &agr;) —S(═O)k—NR6R7, in which  k is 1 or 2,  wherein under the proviso that R6 and R7 cannot be simultaneously hydrogen &agr;1) R6, R7 can be identical or different from one another and represent an aliphatic, carbocyclic, heterocyclic, carbocyclic-aliphatic or heterocyclic-aliphatic radical; hydrogen or lower aliphatic acyl; or &agr;2) R6 and R7 together are an alkylene or alkenylene radical having from 3 up to and including 9 C atoms, in which 1-3 C atoms can be replaced by oxygen, sulfur or nitrogen, &bgr;) N-(aryl lower alkyl)carbamoyl, or &ggr;) a radical of the formula —NH—S(═O)i—R8, in which  i is 1 or 2,  R8 is an aliphatic, carbocyclic or heterocyclic radical; or &dgr;) a radical of the formula —NH—C(═O)—R9,  and the other variable substituents are as defined herein.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: July 27, 2004
    Assignee: Novartis AG
    Inventors: Patricia Imbach, Hans-Georg Capraro, Jürg Zimmermann, Giorgio Caravatti, Pascal Furet, Wolfgang Karl-Diether Brill
  • Publication number: 20020115858
    Abstract: The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of formula 1, which may be used for example for tumor therapy.
    Type: Application
    Filed: November 16, 2001
    Publication date: August 22, 2002
    Inventors: Juerg Zimmermann, Bertrand Sutter, Hans M. Buerger
  • Patent number: RE43932
    Abstract: The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-yl-methyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of formula I, which may be used for example for tumour therapy.
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: January 15, 2013
    Assignee: Novartis AG
    Inventors: Juerg Zimmermann, Bertrand Sutter, Hans Michael Buerger