Abstract: The invention concerns novel compounds of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl), their synthesis method and cosmetic, hygienic or pharmaceutical compositions containing them. The invention also concerns the use, in a physiologically acceptable medium, in or for preparing a soothing composition, of at least a compound of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl). The invention further concerns the use, in a physiologically acceptable medium, in or for producing a composition, of at least a compound of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl), the compound or the composition being designed to soothe skin troubles such as sensitive skins, discomfort, gnawing, itching, irritations, red spots, heat and/or flush sensations, advantageously sensitive and/or irritable and/or reactive and/or allergic symptoms of the skin and/or the scalp and/or mucosa.

Abstract: The invention concerns novel compounds of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl), their synthesis method and cosmetic, hygienic or pharmaceutical compositions containing them The invention also concerns the use, in a physiologically acceptable medium, in or for preparing a soothing composition, of at least a compound of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl). The invention further concerns the use, in a physiologically acceptable medium, in or for preparing a composition, a compound of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl), the compound and the composition being designed for soothing skin troubles such as sensitive skins, discomfort, gnawing, itching, irritations, red spots, heat and/or flush sensations, advantageously sensitive and/or irritable and/or reactive and/or allergic symptoms of the skin and/or the scalp and/or mucosa.

Abstract: Novel alkylenediaminediacetic acid or alkylenediaminetriacetic derivatives of formula (I): or an organic or inorganic salt thereof, their process of preparation, and their use in cosmetic and pharmaceutical compositions, such as for protecting the body against oxidative stress are discussed.

Abstract: A process for the preparation of oxazoles of formula (II): by reaction of thiourea with the corresponding diketone ester.

Abstract: The subject-matter of the present invention is novel compounds of the type of esters derived from alkylenediaminediacetic acid or alkylenediaminetriacetic acid and their-process of preparation. The invention also relates to the use of these compounds in cosmetic and pharmaceutical compositions, in particular for protecting the body against oxidative stress.

Abstract: Novel alkylenediaminediacetic acid or alkylenediaminetriacetic derivatives of formula (I): or an organic or inorganic salt thereof, their process of preparation, and their use in cosmetic and pharmaceutical compositions, such as for protecting the body against oxidative stress are discussed.

Abstract: The invention relates to the use of an ethylenediamine derivative as a substance P antagonist and/or as a local analgesic in, or for the preparation of, a cosmetic or dermatological composition for treating sensitive skin-types. The invention relates in particular to the use of this derivative for preventing and/or combating skin irritations and/or dartres and/or erythema and/or dysaesthesic sensations and/or sensations of inflammation and/or pruritus of the skin and/or the mucous membranes including the eyes. The invention also relates to a composition containing a product having an irritant side effect and this derivative, so as to reduce this irritant effect or even to remove it altogether.

Abstract: These compounds correspond to the following general formula: ##STR1## where: n is 0, 1, or 2,m is are 1, 2, or 3,R, R.sub.1, R.sub.2, and R.sub.3, whether identical or different, represent an atom of hydrogen or a linear or branched alkyl radical at C.sub.1 -C.sub.4,R.sub.1 and R.sub.2, or R.sub.2 and R.sub.3 taken together can form a 5- or 6-group cycle,X and Y, whether identical or different, represent a nitrogenous aromatic heterocycle in position 2,Z.sub.1, Z.sub.2, and Z.sub.3, whether identical or different, represent an atom of hydrogen, a linear or branched alkyl radical at C.sub.1 -C.sub.4, the radical --OR.sub.4 or --NR.sub.4 R'.sub.4,R.sub.4 and R'.sub.4 represent an atom of hydrogen or a linear or branched alkyl radical at C.sub.1 -C.sub.4,and the metallic salts and complexes thereof.Use in pharmaceutical and cosmetic compositions to protect the organism from oxidizing stress situations linked to certain pathological states.

Abstract: The invention relates to the use of an ethylenediamine derivative as a substance P antagonist and/or as a local analgesic in, or for the preparation of, a cosmetic or dermatological composition for treating sensitive skin-types. The invention relates in particular to the use of this derivative for preventing and/or combating skin irritations and/or dartres and/or erythema and/or dysaesthesic sensations and/or sensations of inflammation and/or pruritus of the skin and/or the mucous membranes including the eyes. The invention also relates to a composition containing a product having an irritant side effect and this derivative, so as to reduce this irritant effect or even to remove it altogether.

Abstract: Chelating agents for a transition metal, which exhibit the special feature of being photocleavable, that is containing a chelating functional group blocked by a photocleavable protecting group such that the chelating functional group is released only on exposure to luminous, specially ultraviolet, radiation, trap the transition metals released by the action of the luminous radiation, without exhibiting the side effects observed with conventional chelating agents. Compositions, especially cosmetic and/or dermatological ones, containing at least one such chelating agent are useful for protecting the skin, the mucosa, and/or the hair against ultraviolet radiation.

Abstract: N-arylmethylene ethylenediaminetriacetate, N-arylmethylene iminodiacetate or N,N'-diarylmethylene ethylenediaminediacetate type compounds and their use in combatting oxidative stress, and pharmaceutical and cosmetic compositions comprising said compounds. The invention also concerns a process for the preparation of said compounds.

Abstract: N-arylmethylene ethylenediaminetriacetate, N-arylmethylene iminodiacetate or N,N'-diarylmethylene ethylenediaminediacetate type compounds and their use in combatting oxidative stress, and pharmaceutical and cosmetic compositions comprising said compounds. The invention also concerns a process for the preparation of said compounds.

Abstract: Pyrimidine 3-oxide derivatives and their use for the treatment of hair loss. The compositions contain in a physiologically acceptable medium at least one compound corresponding to the formula (I): ##STR1## in which: R.sub.1 denotes a methyl or NHR.sub.4 group in which R.sub.4 denotes a C.sub.1 -C.sub.4 alkyl group or hydrogen;R.sub.2 denotes hydrogen or a group NHR.sub.4 in which R.sub.4 has the same meaning as above; R.sub.2 may also denote methyl when R.sub.1 denotes methyl; when R.sub.1 denotes NH.sub.2, R.sub.2 cannot be hydrogen;R.sub.3 may denote a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group which may optionally carry;a group OR.sub.5 in which R.sub.5 denotes a C.sub.1 -C.sub.4 alkyl group,a benzene nucleus which is optionally substituted by one or more C.sub.1 -C.sub.4 alkoxy groups;R.sub.3 may also denote a halogen atom or a nitro or amino group;and the physiologically acceptable acid addition salts.

Abstract: The invention relates to compounds of formula: ##STR1## in which: R.sub.1 and R.sub.2 denote, independently of one another, a hydrogen atom or alternatively a carbamoyl group of formula: ##STR2## with R'.sub.3 denoting hydrogen or R.sub.3 ; an alkoxycarbonyl group of formula: ##STR3## or an acyl group of formula: ##STR4## in which formulae R.sub.3 denotes an alkyl, alkenyl or cycloalkyl radical; R.sub.3 can also denote an aryl or aralkyl radical; andR denotes a linear or braanched C.sub.1 -C.sub.8 alkyl radical substituted with one or more halogen atoms, and to their use for the treatment and prevention of hair loss and for stimulating its regrowth.

Abstract: New 2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and the prevention of hair loss.The compounds correspond to the formula: ##STR1## in which: R.sub.1 and R.sub.2 denote hydrogen or the groups of formula: ##STR2## with R'.sub.3 =H or R.sub.3, in which R.sub.3 denotes alkyl, alkenyl or cycloalkyl; R.sub.3 may also denote an aryl or aralkyl radical.R denotes alkyl, alkenyl or cycloalkyl capable of bearing an unsaturation or alkyl bearing an aromatic or heterocyclic nucleus.