Publication number: 20100261719
Abstract: In one aspect, the present invention relates to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, wherein: n is 1 to 4; and R3 in each occurrence is independently selected from —X—R5, —W—R6, —C(O)—N(R3a)—S(O)2—R3b, —C(R3a)?N—R3y, C(R3a)?N—N(R3a)—C(O)—R3b, C(R3a)?N—N(R3a)—C(O)2—R3b, —C(R3a)?N—N(R3y)2, —C(R3a)?N—N(R3a)—C(O)—N(R3y)2, —C(NR3a)2)?N—R3y, —C(N(R3a)2)?N—OR3y, —C(N(R3a)2)?N—C(O)—R3b, —C(N(R3a)2?N—S(0)2—R3b, —C(N(R3a)2)?N—CN, —N?C(R3y)2, —N(R3a)—S(O)2—N(R3y)2, —N(R3a)—N(R3y2, —N(R3a)—C(O)—N(R3y)2, —N(R3a)—C(O)—N(R3a)—S(O)2—R3b, —N(R3a)—C(R3a)?N(R3y), —N(R3a)—C(R3a)?N—OR3y, —N(R3a)—C(R3a)?N—C(O)—R3b, —N(R3a)—C(R3a)?N—S(O)2R—3b, —N(R3a)—C(R3a)?N—CN, —N(R3a)—C(N(R3a)2)?N—R3y, —N(R3a)—C(N(R3a)2)?N—OR3y, —N(R3a)—C(N(R3a)2)?N—C(O)—R3b, —N(R3a)—C(N(R3a)2)—N—S(O)2—R3b, —N(R3a)—C(N(R3a)2)—N—CN, —O—C(O)—R3, and —Si(R3b)3; to methods of using them to treat bacterial infections, and to methods for their preparation.
Type:
Application
Filed:
July 1, 2008
Publication date:
October 14, 2010
Inventors:
Gregory Steven Basarab, Jacques Dumas, Pamela Hill
