Patents by Inventor Jacques-Pierre Moreau

Jacques-Pierre Moreau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060211607
    Abstract: Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo.
    Type: Application
    Filed: May 15, 2006
    Publication date: September 21, 2006
    Inventors: Michael Culler, Zheng Dong, Sun Kim, Jacques-Pierre Moreau
  • Patent number: 7109166
    Abstract: This invention is directed to a sustained release composition comprised of Compound (A) having the formula or a pharmaceutically acceptable salt thereof, and a copolymer comprised of poly-(I)-lactic-glycolic-tartaric acid wherein the amino group of Compound (A) is ionically bound to a carboxyl group of the copolymer and wherein further the composition may be made into a sustained release pharmaceutical composition with pharmaceutically acceptable carrier(s).
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: September 19, 2006
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques, SAS
    Inventor: Jacques-Pierre Moreau
  • Patent number: 7005420
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: February 28, 2006
    Assignee: Ipsen Manufacturing Ireland Limited
    Inventors: Shalaby W. Shalaby, Ruth M. Russell, Jacques-Pierre Moreau, Steven A. Jackson, Francis X. Ignatious
  • Publication number: 20050130900
    Abstract: The invention features a method of administering one or more therapeutic agents to a patient and delivering said agent or agents continuously over an extended period of time, said method comprising: obtaining a pharmaceutical composition including a peptide carrier, one or more therapeutic agents, and up to 30 percent, by weight, of a pharmaceutically acceptable, soluble, monomeric carrier; and parenterally administering said pharmaceutical composition to a subject by injection, wherein said composition automatically forms a gel after interaction with the patient's bodily fluids and releases said peptide carrier and said agent or agents continuously within the patient over an extended period.
    Type: Application
    Filed: March 4, 2003
    Publication date: June 16, 2005
    Inventors: Jacques-Pierre Moreau, Roland Cherif-Cheikh
  • Publication number: 20050089576
    Abstract: This invention pertains to a sustained release complex, Compound (I), which comprises Compound (A), having the formula or a pharmaceutically acceptable salt thereof, and a copolymer comprising poly-(I)-lactic-glycolic-tartaric acid (P(I)LGT), wherein the amino group of said Compound (A) is ionically bound to a carboxyl group of the P(I)LGT. The present invention further pertains to a process for making said sustained release complex. Further still, the present invention is directed to a pharmaceutical composition comprising said sustained release complex and a pharmaceutically acceptable carrier(s).
    Type: Application
    Filed: November 16, 2004
    Publication date: April 28, 2005
    Inventor: Jacques-Pierre Moreau
  • Patent number: 6867181
    Abstract: A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing polymer and a free amino group-containing drug which are ionically bonded to each other.
    Type: Grant
    Filed: January 26, 2000
    Date of Patent: March 15, 2005
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques, S.A.S., Poly-Med, Incorporated
    Inventors: Shalaby Wahba Shalaby, Steven A. Jackson, Jacques-Pierre Moreau
  • Publication number: 20050026827
    Abstract: A linear (i.e., non-cyclic) analog of biologically active amphibian bombesin, mammalian gastrin-releasing peptide (GRP), or mammalian growth hormone releasing factor (GRF), having an active site and a binding site responsible for the binding of the peptide to a receptor on a target cell. Cleavage of a peptide bond in the active site of naturally occurring bombesin, GRP, or GRF is unnecessary for in vivo biological activity. The analog has one of the following modifications: (a) a deletion of an amino acid residue within the active site and a modification of an amino acid residue outside of the active site, (b) a replacement of two amino acid residues within the active site with a synthetic amino acid, a ?-amino acid, or a ?-amino acid residue, or (c) a non-peptide bond. instead of a peptide bond between an amino acid residue of the active site and an adjacent amino acid residue.
    Type: Application
    Filed: February 27, 2004
    Publication date: February 3, 2005
    Inventors: David Coy, Jacques-Pierre Moreau, Sun Kim
  • Publication number: 20050009741
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Application
    Filed: July 27, 2004
    Publication date: January 13, 2005
    Inventors: Shalaby Shalaby, Ruth Russell, Jacques-Pierre Moreau, Steven Jackson, Francis Ignatious
  • Publication number: 20040209798
    Abstract: Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo.
    Type: Application
    Filed: May 17, 2004
    Publication date: October 21, 2004
    Inventors: Michael D Culler, Zheng Xin Dong, Sun H Kim, Jacques-Pierre Moreau
  • Patent number: 6794364
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: September 21, 2004
    Assignee: Kinerton Limited
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis X. Ignatious, Jacques-Pierre Moreau, Ruth M. Russell
  • Patent number: 6685959
    Abstract: The invention relates to novel pharmaceutical compositions comprising 2-isoxazole-8-aminotetralin derivatives. The invention more specifically relates to compositions in the form of a patch comprising a therapeutically efficacious amount of a derivative of 2-isoxazole-8-aminotetraline, especially 1,2,3,4-tetrahydro-8(5-isoxazolyl)N-N-diisopropyl-2-naphtalenamine. The invention also relates to a 2-isoxazole-8-aminotetralin derivative, especially 1,2,3,4-tetrahydro-8-(5-isoxazolyl)-N,N-diisopropyl-2-naphtalenamine, which is used to produce a medicament which can be administered transdermally to treat irritable bowel syndrome.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: February 3, 2004
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Jacques Pierre Moreau, BĂ©atrice Guimbert, Marc Pellet
  • Publication number: 20030092800
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Application
    Filed: September 20, 2002
    Publication date: May 15, 2003
    Applicant: Biomeasure, Inc.
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis X. Ignatious, Jacques-Pierre Moreau, Ruth M. Russell
  • Publication number: 20030050436
    Abstract: A linear (i.e., non-cyclic) analog of biologically active amphibian bombesin, mammalian gastrin-releasing peptide (GRP), or mammalian growth hormone releasing factor (GRF), having an active site and a binding site responsible for the binding of the peptide to a receptor on a target cell. Cleavage of a peptide bond in the active site of naturally occurring bombesin, GRP, or GRF is unnecessary for in vivo biological activity. The analog has one of the following modifications: (a) a deletion of an amino acid residue within the active site and a modification of an amino acid residue outside of the active site, (b) a replacement of two amino acid residues within the active site with a synthetic amino acid, a &bgr;-amino acid, or a &ggr;-amino acid residue, or (c) a non-peptide bond instead of a peptide bond between an amino acid residue of the active site and an adjacent amino acid residue.
    Type: Application
    Filed: October 23, 2001
    Publication date: March 13, 2003
    Applicant: Biomeasure Inc., Massachusetts corporation
    Inventors: David H. Coy, Jacques-Pierre Moreau, Sun Hyuk Kim
  • Publication number: 20030026857
    Abstract: The invention features a method of identifying a pharmaceutical comprising compounds found in a plant extract by utilizing a genomic screen of the plant extract.
    Type: Application
    Filed: October 8, 2002
    Publication date: February 6, 2003
    Applicant: Societe De Conseils De Recherches Et D'Applications Scientifiques, S.A.S.
    Inventors: Albert Beaufour, Jacques-Pierre Moreau
  • Patent number: 6479457
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: November 12, 2002
    Assignee: Kinerton Limited
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis X. Ignatious, Jacques-Pierre Moreau, Ruth M. Russell
  • Publication number: 20020098206
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Application
    Filed: October 9, 1998
    Publication date: July 25, 2002
    Inventors: SHALABY W. SHALABY, STEVEN A. JACKSON, FRANCIS X. IGNATIOUS, JACQUES-PIERRE MOREAU, RUTH M. RUSSELL
  • Publication number: 20020018989
    Abstract: The invention features a method of identifying a pharmaceutical comprising compounds found in a plant extract by utilizing a genomic screen of the plant extract.
    Type: Application
    Filed: November 7, 1996
    Publication date: February 14, 2002
    Inventors: ALBERT BEAUFOUR, JACQUES-PIERRE MOREAU
  • Patent number: 6307017
    Abstract: A linear (i.e., non-cyclic) analog of biologically active amphibian bombesin, mammalian gastrin-releasing peptide (GRP), or mammalian growth hormone releasing factor (GRF), having an active site and a binding site responsible for the binding of the peptide to a receptor on a target cell. Cleavage of a peptide bond in the active site of naturally occurring bombesin, GRP, or GRF is unnecessary for in vivo biological activity. The analog has one of the following modifications: (a) a deletion of an amino acid residue within the active site and a modification of an amino acid residue outside of the active site, (b) a replacement of two amino acid residues within the active site with a synthetic amino acid, a &bgr;-amino acid, or a &ggr;-amino acid residue, or (c) a non-peptide bond instead of a peptide bond between an amino acid residue of the active site and an adjacent amino acid residue.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: October 23, 2001
    Assignees: Biomeasure, Incorporated, The Administrators of the Tulane Educational Fund
    Inventors: David H. Coy, Jacques-Pierre Moreau, Sun Hyuk Kim
  • Patent number: 6221958
    Abstract: Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50% by weight of the polypeptide present in the composition is ionically conjugated to the polyester.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: April 24, 2001
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques, SAS, Poly-Med Incorporated
    Inventors: Shalaby Wahba Shalaby, Steven A. Jackson, Jacques-Pierre Moreau
  • Patent number: 6150333
    Abstract: The present invention is directed to a method of treating one or more of the following disease and/or conditions, which comprises administering to a patient in need thereof the compound H-.beta.-D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH.sub.2, where the Cysteines are bonded by a disulfide bond, or a pharmaceutically acceptable salt thereof, most preferably the acetate salt of the compound, in the treatment of certain diseases and/or conditions such as gastroenterological conditions and/or diseases, endocrinological diseases and/or conditions, various types of cancers and conditions associated with cancer such as cancer cachexia and in the treatment of hypotension and panic attacks.
    Type: Grant
    Filed: July 26, 1999
    Date of Patent: November 21, 2000
    Assignee: Biomeasure, Inc.
    Inventor: Jacques-Pierre Moreau