Abstract: The present invention provides a pharmaceutical composition for prevention or treatment of a stress disease and depression, the pharmaceutical composition be safely useable without toxicity and side effects by using an extract of leaves of Vaccinium bracteatum Thunb., which is natural resource of Korea, so that the reduction of manufacturing and production costs and the import substitution and export effects can be expected through the replacement of a raw material for preparation with a plant inhabiting in nature.

Abstract: A display device includes a first semiconductor layer disposed on a substrate; a first insulating layer disposed on the first semiconductor layer; a scan line disposed on the first insulating layer; a second insulating layer on the scan line; an inverted scan line on the second insulating layer; a third insulating layer disposed on the inverted scan line; a second semiconductor layer disposed on the third insulating layer; a fourth insulating layer disposed on the second semiconductor layer; an initializing voltage line disposed on the fourth insulating layer and overlapping the scan line; a first transistor including a channel disposed in the first semiconductor layer and receiving a gate signal through the scan line; and a second transistor including a channel disposed in the second semiconductor layer and receiving a gate signal through the inverted scan line.

Abstract: A packaging device including bumps and a method of manufacturing the packaging device are presented. In the method of manufacturing a packaging device, a dielectric layer that covers a packaging base is formed and a lower layer is formed over a packaging base including first and second connecting pads. A plurality of dummy bumps that overlaps with the dielectric layer is formed. A sealing pattern that covers the dummy bumps, filling areas between the dummy bumps, is formed. A lower layer pattern in which the plurality of dummy bumps have been disposed is formed by removing portions of the lower layer that are exposed and do not overlap with the sealing pattern.

Abstract: A dual set-up zoom actuator includes a first carrier having a first lens and movable along an optical axis, a second carrier having a second lens and being capable of moving anterior or posterior to the first carrier along the optical axis, a housing enclosing the first and second carriers, a first coil unit equipped to the housing and having n, which is a natural number not less than two, first coils disposed anterior or posterior along the optical axis, a second coil unit equipped to the housing at a location different than the first coil unit and having n+1 second coils disposed anterior or posterior along the optical axis, a first magnet having n+1 magnetic poles facing the first coil unit and mounted on the first carrier, and a second magnet having n magnetic poles facing the second coil unit and mounted on the second carrier.

Abstract: The present disclosure relates to a cell selection apparatus and method and, in particular, may provide an apparatus that classifies cells by using artificial intelligence, on the basis of the homogeneity of cells from an image pre-processed from image data obtained by capturing images of cells, and marks parts that have an important influence on the classification results, thereby increasing the accuracy of cell selection. In addition, a reliable selection basis can be provided by visualizing the basis for cell selection.

Abstract: An actuator for a reflector according to an embodiment of the present disclosure includes a moving frame having a reflector configured to reflect light to a lens, and a magnet, a base frame configured to provide a moving space for the moving frame, a driving coil configured to generate a magnetic force at the magnet so that the moving frame rotates based on the base frame, a guide rail formed at any one of the moving frame and base frame and having a rounded shape, a holder provided to any one of the moving frame and the base frame not provided with the guide rail, provided in a direction facing the guide rail, and having a groove shape; and a ball arranged between the guide rail and the holder.

Abstract: Disclosed are an in-vessel control rod drive mechanism and a nuclear reactor with the same. The in-vessel control rod drive mechanism includes a control rod drive mechanism for regulating and a control rod drive mechanism for shutdown provided at an upper or lower space of a reactor core to insert or withdraw a regulating rod and a shutdown rod into/from the reactor core based on an operation state of the nuclear reactor, wherein the control rod drive mechanism for regulating and the control rod drive mechanism for shutdown are alternately arranged in the vertical direction. Therefore, a space of containment can be minimized due to the installation of the in-vessel control rod drive mechanism, and thus a rod ejection accident can be prevented, and a loss-of-coolant accident can be reduced.

Abstract: A magnetostrictive wire control rod position indicator for determining a real-time position of a control rod using a mutual interference effect between a magnetic field formed by supplying a pulse current to a magnetostrictive wire provided inside a protecting tube and a magnetic field formed by a permanent magnet of a drive shaft includes magnet members installed at an upper limit position and a lower limit position of the magnetostrictive wire control rod position indicator to cause magnetic field interference with the permanent magnet of the drive shaft.

Abstract: Disclosed is a control rod drive mechanism. More specifically, the control rod drive mechanism includes a guide member 100 disposed in a nuclear reactor to receiving a drive shaft 2; a latch assembly 200 disposed in the guide member 100 to enable the drive shaft 2 to be withdrawn and inserted; a supporting member 300 connected to the guide member 100 to cover the drive shaft 2 and to support the latch assembly 200; and a plurality of coil housings 400 spaced apart and connected to the guide member 100 to cover the latch assembly 200, and each having a coil 410 built therein.

Abstract: The present invention relates to a composition for preventing or treating immune diseases through the suppression of B cell activity induced by metformin. More particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by suppression or reduction of B cell activity which is a cause of disease. The present invention can be valuable in the use thereof for various autoimmune diseases as an immunosuppressant which can prevent or treat immune diseases by suppressing or reducing B cell activity and Th17 cell activity, which are causes of disease, or by promoting or increasing regulatory T cell activity.

Abstract: Provided is a composition for inducing tumor cell senescence and a method for inducing tumor cell senescence using the same. The composition can inhibit a PAPSS2 gene in a tumor cell to thereby induce senescence of the tumor cell, and if the composition is used concurrently with irradiation of the tumor cell, the composition can improve the sensitivity of the tumor cell to radiation.

Abstract: A magnetostrictive wire control rod position indicator for determining a real-time position of a control rod using a mutual interference effect between a magnetic field formed by supplying a pulse current to a magnetostrictive wire provided inside a protecting tube and a magnetic field formed by a permanent magnet of a drive shaft includes magnet members installed at an upper limit position and a lower limit position of the magnetostrictive wire control rod position indicator to cause magnetic field interference with the permanent magnet of the drive shaft.

Abstract: The present invention relates to a composition for preventing or treating immune diseases through the suppression of B cell activity induced by metformin. More particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by suppression or reduction of B cell activity which is a cause of disease. The present invention can be valuable in the use thereof for various autoimmune diseases as an immunosuppressant which can prevent or treat immune diseases by suppressing or reducing B cell activity and Th17 cell activity, which are causes of disease, or by promoting or increasing regulatory T cell activity.

Abstract: Disclosed are an in-vessel control rod drive mechanism and a nuclear reactor with the same. The in-vessel control rod drive mechanism includes a control rod drive mechanism for regulating and a control rod drive mechanism for shutdown provided at an upper or lower space of a reactor core to insert or withdraw a regulating rod and a shutdown rod into/from the reactor core based on an operation state of the nuclear reactor, wherein the control rod drive mechanism for regulating and the control rod drive mechanism for shutdown are alternately arranged in the vertical direction. Therefore, a space of containment can be minimized due to the installation of the in-vessel control rod drive mechanism, and thus a rod ejection accident can be prevented, and a loss-of-coolant accident can be reduced.

Abstract: Disclosed is a control rod drive mechanism. More specifically, the control rod drive mechanism includes a guide member 100 disposed in a nuclear reactor to receiving a drive shaft 2; a latch assembly 200 disposed in the guide member 100 to enable the drive shaft 2 to be withdrawn and inserted; a supporting member 300 connected to the guide member 100 to cover the drive shaft 2 and to support the latch assembly 200; and a plurality of coil housings 400 spaced apart and connected to the guide member 100 to cover the latch assembly 200, and each having a coil 410 built therein.

Abstract: Disclosed is an anticancer composition, comprising an inhibitor against WIG1 and/or YPEL5 or against a protein encoded by the gene. A composition for screening an anticancer agent comprising a nucleic acid having a sequence complementary to an mRNA of WIG1 and/or YPEL5, or an antibody to a protein encoded by the gene is also provided. Also, a method is provided for screening an anticancer agent, which comprises: (A) quantitatively analyzing expression of WIG1 and/or YPEL5 at an mRNA or protein level in a tumor cell which is not treated with a candidate for an anticancer agent; (B) quantitatively analyzing expression of the gene at an mRNA or protein level in a tumor cell after treatment of the candidate for an anticancer agent; and (C) selecting the candidate if the expression level of the gene is increased in step (B), compared to step (A).

Abstract: Disclosed is an anticancer composition, comprising an inhibitor against WIG1 and/or YPEL5 or against a protein encoded by the gene. A composition for screening an anticancer agent comprising a nucleic acid having a sequence complementary to an mRNA of WIG1 and/or YPEL5, or an antibody to a protein encoded by the gene is also provided. Also, a method is provided for screening an anticancer agent, which comprises: (A) quantitatively analyzing expression of WIG1 and/or YPEL5 at an mRNA or protein level in a tumor cell which is not treated with a candidate for an anticancer agent; (B) quantitatively analyzing expression of the gene at an mRNA or protein level in a tumor cell after treatment of the candidate for an anticancer agent; and (C) selecting the candidate if the expression level of the gene is increased in step (B), compared to step (A).