Patents by Inventor Jailall Ramnauth

Jailall Ramnauth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts, prodrugs and polymorphs of fab I inhibitors
    Patent number: 9862737
    Abstract: In part, the present invention is directed to antibacterial compounds and salts thereof.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: January 9, 2018
    Assignee: Debiopharm International SA
    Inventors: Henry Pauls, Jailall Ramnauth
  • Acrylamide derivatives as Fab I inhibitors
    Patent number: 8895545
    Abstract: In part, the present invention is directed to antibacterial compounds.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: November 25, 2014
    Assignee: Debiopharm International SA
    Inventors: Heinz W. Pauls, Jailall Ramnauth, Peter Sampson, Andras Toro
  • SALTS, PRODRUGS AND POLYMORPHS OF FAB I INHIBITORS
    Publication number: 20140309191
    Abstract: In part, the present invention is directed to antibacterial compounds and salts thereof.
    Type: Application
    Filed: November 8, 2013
    Publication date: October 16, 2014
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Henry Pauls, Jailall Ramnauth
  • BENZOXAZINES, BENZOTHIAZINES, AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY
    Publication number: 20140163016
    Abstract: The present invention features benzoxazines, benzothiazines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 12, 2014
    Applicant: NeurAxon, Inc.
    Inventors: Jailall RAMNAUTH, Subhash C. Annedi, Sarah Silverman, Peter Dove, Shawn Maddaford, Suman Rakhit
  • Indole compounds and methods for treating visceral pain
    Patent number: 8673909
    Abstract: The invention features methods of treating visceral pain or a condition in a mammal caused by the action of nitric oxide synthase (NOS) or by the action of serotonin 5HT1D/1B receptors, by administering to a patient in need thereof a therapeutically effective amount of an indole compound of Formula (I), or a pharmaceutically acceptable salt or prodrug thereof. The methods of the invention may further comprise the administration of additional therapeutic agent. The invention also features new compounds of Formula (I), pharmaceutical compositions thereof, and methods of resolving enantiomeric mixtures.
    Type: Grant
    Filed: November 17, 2008
    Date of Patent: March 18, 2014
    Assignee: NeurAxon, Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash C. Annedi, John S. Andrews, Gabriela Mladenova
  • SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY
    Publication number: 20140051687
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.
    Type: Application
    Filed: October 21, 2013
    Publication date: February 20, 2014
    Applicant: NeurAxon, Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash C. Annedi
  • Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity
    Patent number: 8618286
    Abstract: The present invention features benzoxazines, benzothiazines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. Exemplary compounds are of the formula: The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: December 31, 2013
    Assignee: NeurAxon, Inc.
    Inventors: Jailall Ramnauth, Subhash C. Annedi, Sarah Silverman, Peter Dove, Shawn Maddaford, Suman Rakhit
  • Substituted indole compounds having NOS inhibitory activity
    Patent number: 8586620
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: November 19, 2013
    Assignee: NeurAxon, Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash C. Annedi
  • ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS
    Publication number: 20130237523
    Abstract: In part, the present invention is directed to antibacterial compounds.
    Type: Application
    Filed: October 4, 2012
    Publication date: September 12, 2013
    Applicant: AFFINIUM PHARMACEUTICALS, INC.
    Inventors: Heinz W. Pauls, Jailall Ramnauth, Peter Sampson, Andras Toro
  • SALTS, PRODRUGS AND POLYMORPHS OF FAB I INHIBITORS
    Publication number: 20130150400
    Abstract: In part, the present invention is directed to antibacterial compounds and salts thereof.
    Type: Application
    Filed: August 9, 2012
    Publication date: June 13, 2013
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Henry Pauls, Jailall Ramnauth
  • Therapeutic agents, and methods of making and using the same
    Patent number: 8450307
    Abstract: In part, the present invention is directed to antibacterial compounds.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: May 28, 2013
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Bruce J. Sargent, Henry Pauls, Judd M. Berman, Jailall Ramnauth, Peter Sampson, Andras Toro, Fernando J. Martin, Matthew D. Surman, Helene Y. Decornez, David D. Manning
  • Acrylamide derivatives as Fab I inhibitors
    Patent number: 8318720
    Abstract: In part, the present invention is directed to antibacterial compounds.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: November 27, 2012
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Heinz W. Pauls, Jailall Ramnauth, Peter Sampson, Andras Toro
  • Salts, prodrugs and polymorphs of fab I inhibitors
    Patent number: 8263613
    Abstract: In part, the present invention is directed to antibacterial compounds and salts thereof.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: September 11, 2012
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Henry Pauls, Jailall Ramnauth
  • BENZOXAZINES, BENZOTHIAZINES, AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY
    Publication number: 20120122855
    Abstract: The present invention features benzoxazines, benzothiazines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
    Type: Application
    Filed: January 27, 2012
    Publication date: May 17, 2012
    Applicant: NeurAxon, Inc.
    Inventors: Jailall RAMNAUTH, Subhash C. Annedi, Sarah Silverman, Peter Dove, Shawn Maddaford, Suman Rakhit
  • Quinolone and tetrahydroquinolone and related compounds having NOS inhibitory activity
    Patent number: 8173813
    Abstract: The present invention features quinolones, tetrahydroquinolines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: May 8, 2012
    Assignee: NeurAxon, Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Subhash C. Annedi, John Andrews, Peter Dove, Sarah Silverman, Paul Renton
  • Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity
    Patent number: 8106043
    Abstract: The present invention features benzothiazines that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms, and that have the formula: The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
    Type: Grant
    Filed: July 6, 2009
    Date of Patent: January 31, 2012
    Assignee: NeurAxon, Inc.
    Inventors: Jailall Ramnauth, Subhash C. Annedi, Sarah Silverman, Peter Dove, Shawn Maddaford, Suman Rakhit
  • SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY
    Publication number: 20110212947
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Applicant: NeurAxon Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash C. Annedi
  • 1,5 and 3,6-substituted indole compounds having NOS inhibitory activity
    Patent number: 7989447
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, or chronic pain.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: August 2, 2011
    Assignee: NeurAxon, Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash C. Annedi
  • Substituted indole compounds having NOS inhibitory activity
    Patent number: 7951940
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: May 31, 2011
    Assignee: NeurAxon, Inc.
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash C. Annedi
  • Heterocyclic Compounds, Methods of Making Them and Their Use in Therapy
    Publication number: 20110124633
    Abstract: In part, the present invention is directed to antibacterial compounds.
    Type: Application
    Filed: July 27, 2010
    Publication date: May 26, 2011
    Inventors: Judd Berman, Peter Sampson, Heinz W. Pauls, Jailall Ramnauth, David Douglas Manning, Matthew David Surman, Dejian Xie, Helene Yvonne Decornez