Patents by Inventor James A. Italia

James A. Italia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Universal platform for genetic code expansion
    Patent number: 11760990
    Abstract: Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a novel E. coli tryptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: September 19, 2023
    Assignee: Trustees of Boston College
    Inventors: Abhishek Chatterjee, James Italia
  • Universal Platform for Genetic Code Expansion
    Publication number: 20210002626
    Abstract: Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a novel E. coli tyrptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.
    Type: Application
    Filed: July 21, 2020
    Publication date: January 7, 2021
    Inventors: Abhishek Chatterjee, James Italia
  • Universal Platform for Genetic Code Expansion
    Publication number: 20200407705
    Abstract: Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a novel E.coli tyrptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.
    Type: Application
    Filed: July 21, 2020
    Publication date: December 31, 2020
    Inventors: Abhishek Chatterjee, James Italia
  • Universal platform for genetic code expansion
    Patent number: 10717975
    Abstract: Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a novel E. coli tyrptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: July 21, 2020
    Assignee: TRUSTEES OF BOSTON COLLEGE
    Inventors: Abhishek Chatterjee, James Italia
  • Universal Platform for Genetic Code Expansion
    Publication number: 20170349891
    Abstract: Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a novel E. coli tyrptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 7, 2017
    Inventors: Abhishek Chatterjee, James Italia
  • Pipettor attachable/integrateable microcentrifuge tube opener
    Patent number: 5950504
    Abstract: A pipettor attachable microcentrifuge tube opener adapted to fit on a common pipettor, allowing the user to open a microcentrifuge tube without the need to open the tube solely by hand or through use of an additional instrument. Alternatively, the features of the microcentrifuge tube opener may be integrated into an originally manufactured pipettor.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: September 14, 1999
    Inventor: James A. Italia