Patents by Inventor James C. Yang

James C. Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE
    Publication number: 20110104129
    Abstract: The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for a cancer antigen, e.g., a renal cell carcinoma antigen, wherein the TCR recognizes the cancer antigen in a major histocompatibility complex (MHC)-independent manner. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Application
    Filed: August 30, 2010
    Publication date: May 5, 2011
    Applicant: The USA, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Qiong J. Wang, Kenichi Hanada, James C. Yang
  • T cell receptors and related materials and methods of use
    Patent number: 7820174
    Abstract: The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for a cancer antigen, e.g., a renal cell carcinoma antigen, wherein the TCR recognizes the cancer antigen in a major histocompatibility complex (MHC)-independent manner. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: October 26, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Qiong J. Wang, Kenichi Hanada, James C. Yang
  • T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE
    Publication number: 20090042798
    Abstract: The invention provids an isolated or purified T cell receptor (TCR) having antigenic specificity for a cancer antigen, e.g., a renal cell carcinoma antigen, wherein the TCR recognizes the cancer antigen in a major histocompatibility complex (MHC)-independent manner. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Application
    Filed: August 22, 2008
    Publication date: February 12, 2009
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Qiong J. Wang, Kenichi Hanada, James C. Yang