Abstract: A printed wiring board (PWB) can be fabricated with enhanced thermal characteristics that can enable the use of higher performance electronic components and/or a smaller packaging configuration. A substrate layer of the PWB includes a matrix material and optional reinforcing fibers embedded in the matrix material. The matrix material and/or the reinforcing fibers may include thermally-conductive particles such as nanodiamonds that increase the thermal conductivity of the substrate layer. Holes may be formed through the substrate layer for receiving and/or electrically connecting electronic components. The thermally-conductive particles are sized sufficiently small to allow the formation of the holes through the substrate layer using conventional equipment and processes such as drilling. The PWB may also include a protective coating that comprises thermally-conductive particles.

Abstract: A transmission clutch cooling system includes a clutch housing defined between a drive hub of a drive member and a clutch hub of a driven member and a clutch assembly housed in the clutch housing. The clutch hub includes a hub deck having a plurality of bores therethrough, an inner annulus extending axially from the hub deck, and an outer annulus extending axially from the hub deck, the outer annulus including a plurality of radial orifices therethrough and a lip flange extending from a distal end towards the inner annulus. The clutch assembly includes a plurality of clutch plates secured to the drive hub and a plurality of friction plates secured to the driven member. A piston assembly is provided for engaging or disengaging the plurality of friction plates against the plurality of clutch plates to cause or release integrated rotation of the drive member and the driven member.

Abstract: An apparatus for sampling and storing biological fluids from a human or animal subject is provided. In one embodiment of the present disclosure, the apparatus includes a main body, lancet carrier or hub, lancet, lancet trigger, capillary tube, and sample compartments for collecting and storing dried blood and other bodily fluids. The lancet hub supports a lancet and provides for moving the lancet longitudinally between a first retracted position and a second extended position. The device includes a capillary tube having an internal diameter sized to draw and retain fluid from a contacted source using capillary action. The main body of the apparatus further includes a sample compartment for holding sampling and storage materials. In at least one embodiment of the present disclosure, the sample compartment can be accessed by lifting sample compartment lid. Also included is a new “fan” or “daisy” shaped collection material format for use in collecting and preserving samples.

Abstract: Compounds of formula (I): wherein: W is O, N—H, N-alkyl, N-alkenyl, N-alkynyl, N-aryl, N-heteroaryl or S; each X is independently CH or N; R1 is formula (b) or R3 is H, alkyl, NH2, OH, =0 or halogen; each A and B are independently CH or N; D is NHR4; R4 is H, alkyl, —C(O)-alkyl.

Abstract: A seal is disclosed for retrofitting to an existing railroad hopper car having opposing sidewalls and at least one trough extending between the opposing sidewalls. The seal includes a first member configured to mate against a surface of a trough adjacent a sidewall, the first member including a first edge having angled sections corresponding to angled sections of where the sidewall meets the trough, and a second member integral with the first member and extending substantially upright from the first edge of the first member, the second member configured to mate against a surface of the sidewall adjacent the trough, wherein the second member is angled relative to the first member at each of the angled sections corresponding to angled sections of the sidewall adjacent the trough.

Abstract: A detachable handpiece coupling by a detachable fabric to a flat surface device, electronic tablet or notebook, or other object held in front of a user, the device conforming to a left or right hand of the user with a selected padded insert within a narrow end of the handpiece to reduce the inner portion of the handpiece to further conform to the user's hand.

Abstract: A transmission clutch cooling system includes a clutch housing defined between a drive hub of a drive member and a clutch hub of a driven member and a clutch assembly housed in the clutch housing. The clutch hub includes a hub deck having a plurality of bores therethrough, an inner annulus extending axially from the hub deck, and an outer annulus extending axially from the hub deck, the outer annulus including a plurality of radial orifices therethrough and a lip flange extending from a distal end towards the inner annulus. The clutch assembly includes a plurality of clutch plates secured to the drive hub and a plurality of friction plates secured to the driven member. A piston assembly is provided for engaging or disengaging the plurality of friction plates against the plurality of clutch plates to cause or release integrated rotation of the drive member and the driven member.

Abstract: Systems and methods for displaying digitized waveform data on a pixilated screen are provided. Certain methods include retrieving waveform data that exists as a plurality of sequential samples in a buffer. A first sample is associated with a first point of a pixilated screen. A second sample that follows the first sample is associated with a second point of the screen. A boundary of a rectangular line segment connecting the points is determined. For each pixel of the pixilated screen that has any portion inside the boundary of the rectangular line segment, a number of subpixels within the pixel that have any portion inside the boundary of the rectangular line segment is determined and that number of subpixels is correlated with an intensity value that is then associated with the pixel. Waveform data is displayed by painting pixels of the screen with the associated intensity values.

Abstract: A system, method and computer program for managing resources within an integrated development environment for multiple users. The resources include both content resources and people resources. The method comprises: managing a plurality of nodes representing resources, the nodes including content nodes and person nodes, wherein the node contains a resource reference for referencing the resource; managing one or more links representing one or more relationships between the resources, the links including links between content nodes, between person nodes and between content and person nodes, each link comprising node references to identify the nodes in the relationships and an importance value to identify the importance of the relationship; providing an interface for selecting one of the plurality of content nodes or person nodes; adapting, in response to the user selected node, one or more importance values of certain links.

Abstract: A printed wiring board (PWB) can be fabricated with enhanced thermal characteristics that can enable the use of higher performance electronic components and/or a smaller packaging configuration. A substrate layer of the PWB includes a matrix material and optional reinforcing fibers embedded in the matrix material. The matrix material and/or the reinforcing fibers may include thermally-conductive particles such as nanodiamonds that increase the thermal conductivity of the substrate layer. Holes may be formed through the substrate layer for receiving and/or electrically connecting electronic components. The thermally-conductive particles are sized sufficiently small to allow the formation of the holes through the substrate layer using conventional equipment and processes such as drilling. The PWB may also include a protective coating that comprises thermally-conductive particles.

Abstract: The subject application pertains to a compound of structure IX or X: or a pharmaceutically acceptable salt thereof, wherein: X is —C(?O)N(R10)— or —CH(OPr3) —; R7, R9 and R10 are the same or different and represent hydrogen or an amino acid side chain moiety from either a natural or an unnatural amino acid; Pr1 and Pr2 are the same or different and represent hydrogen or a thiol protecting group; Pr3 is hydrogen or an alcohol protecting group; R1, R2, R5 and R6 are the same or different and represent hydrogen or an amino acid side chain moiety from either a natural or an unnatural amino acid, or R1 and R2 and/or R5 and R6, taken together with the carbon atom to which they are attached, form a spirocyclic moiety, with the proviso that: each of R1 and R2 is not hydrogen, or each of R5 and R6 is not hydrogen.

Abstract: According to the invention, there is provided a method for treating heavy crude oil (HCO) which includes the steps of combining the HCO with an alkane containing solvent to form an HCO/solvent mixture, sonicating this mixture at audio frequency to precipitate asphaltenes from the HCO/solvent mixture, and separating the precipitated asphaltenes from the HCO/solvent mixture.

Abstract: An apparatus for sampling and storing biological fluids from a human or animal subject is provided. In one embodiment of the present disclosure, the apparatus includes a main body, lancet carrier or hub, lancet, lancet trigger, capillary tube, and sample compartments for collecting and storing dried blood and other bodily fluids. The lancet hub supports a lancet and provides for moving the lancet longitudinally between a first retracted position and a second extended position. The device includes a capillary tube having an internal diameter sized to draw and retain fluid from a contacted source using capillary action. The main body of the apparatus further includes a sample compartment for holding sampling and storage materials. In at least one embodiment of the present disclosure, the sample compartment can be accessed by lifting sample compartment lid. Also included is a new “fan” or “daisy” shaped collection material format for use in collecting and preserving samples.

Abstract: The pickup bed tool tray apparatus provides a movable, motorized tray that fits between the inner sides of a pickup bed, just below the bed top. The apparatus is therefore not in the way of storing or carrying anything in the bed. By using the control, the tray may be moved fore and aft, as needed, to best access tools and other equipment that may be carried in the tray.

Abstract: Disclosed is an insult-sensing absorbent article including an absorbent assembly, an insult-sensing means coupled to the absorbent assembly, and a tuned antenna system coupled to the insult-sensing means. Also disclosed is a method for indicating an insult to an absorbent article to be worn by a wearer, the method including providing an absorbent article including a conductive element; providing an antenna system associated with the absorbent article, the antenna system including a signal generator and an antenna, wherein the antenna includes the conductive element, and wherein the antenna system is adapted to transmit a signal; and maximizing the receivability of the signal by optimizing an aspect of the antenna system.

Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein: W is O, N—H, N-(C1-C10 alkyl) or S; each X is independently CH or N; R1 is a 5 to 7-membered saturated or unsaturated, optionally substituted heterocycle containing at least 1 heteroatom selected from N or O; R2 is (LQ)mY; and each R3 is independently H, C1-C10 alkyl, aryl or heteroaryl, are surprisingly found to be inhibitors of PI3K-p110?, and therefore have utility in therapy.

Abstract: Compounds of formula (I): wherein: W is O, N—H, N-alkyl, N-alkenyl, N-alkynyl, N-aryl, N-heteroaryl or S; each X is independently CH or N; R1 is formula (b) or R3 is H, alkyl, NH2, OH, =0 or halogen; each A and B are independently CH or N; D is NHR4; R4 is H, alkyl, —C(O)— alkyl.

Abstract: A method for monitoring consumption of at least one consumable in a mass transfer system. The method includes providing at least one accurate mass transfer apparatus configured to provide mass transfer of a gas into a liquid to generate a liquid output, wherein the relative amounts of liquid and gas are set, and for each mass transfer apparatus: measuring the amount of liquid output, and determining, based on the amount of liquid output and the relative amounts of liquid and gas, a quantity of at least one of the gas and liquid consumed in that mass transfer apparatus.

Abstract: Systems and methods for displaying digitized waveform data on a pixilated screen are provided. Certain methods include retrieving waveform data that exists as a plurality of sequential samples in a buffer. A first sample is associated with a first point of a pixilated screen. A second sample that follows the first sample is associated with a second point of the screen. A boundary of a rectangular line segment connecting the points is determined. For each pixel of the pixilated screen that has any portion inside the boundary of the rectangular line segment, a number of subpixels within the pixel that have any portion inside the boundary of the rectangular line segment is determined and that number of subpixels is correlated with an intensity value that is then associated with the pixel. Waveform data is displayed by painting pixels of the screen with the associated intensity values.

Abstract: A mobile advertising relay system and related methods for relaying images between a designated server and one or more mobile communication devices. The system includes at least one designated server that is configured to supply images, and a database adapted to record information relating to images, users, image publishers (e.g., advertisers), and interactions therebetween. An image queue is uniquely associated with each mobile device whereby a plurality of images are stored for future presentation to the mobile device user. In embodiments, the image queue is stored in the mobile device to facilitate rapid display of the image upon receipt of an incoming communication. The designated server includes an image selection unit for replenishing images queues, and a user profile unit for recording user preferences and image interactions. Images may be rated by the user to enable future images to be selected in accordance with the user's tastes.