Patents by Inventor James J. Harrison

James J. Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200155474
    Abstract: A method of treating hypoxic tissue such as wound tissue comprises contacting a composition to the hypoxic tissue in a hypoxia-treatment effective amount, the composition comprising a biodegradable polymer and an inorganic peroxide incorporated into the polymer.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 21, 2020
    Inventors: Benjamin S. Harrison, James J. Yoo, Anthony Atala
  • Patent number: 10583112
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: March 10, 2020
    Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Stephen John Atkinson, Emmanuel Hubert Demont, Lee Andrew Harrison, Alexander G. Preston, Jonathan Thomas Seal, Ian David Wall, Robert J. Watson, James Michael Woolven
  • Publication number: 20200009140
    Abstract: The present invention is directed to pyridyl derivatives which are bromodomain inhibitors, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases or conditions
    Type: Application
    Filed: February 27, 2018
    Publication date: January 9, 2020
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Etienne LEVERNIER, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • Patent number: 10493040
    Abstract: A method of treating hypoxic tissue such as wound tissue comprises contacting a composition to the hypoxic tissue in a hypoxia-treatment effective amount, the composition comprising a biodegradable polymer and an inorganic peroxide incorporated into the polymer.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: December 3, 2019
    Assignee: Wake Forest University Health Sciences
    Inventors: Benjamin S. Harrison, James J. Yoo, Anthony Atala
  • Patent number: 10493041
    Abstract: A method of treating hypoxic tissue such as wound tissue comprises contacting a composition to the hypoxic tissue in a hypoxia-treatment effective amount, the composition comprising a biodegradable polymer and an inorganic peroxide incorporated into the polymer.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: December 3, 2019
    Assignee: Wake Forest University Health Sciences
    Inventors: Benjamin C. Harrison, James J. Yoo, Anthony Atala
  • Patent number: 10471050
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: November 12, 2019
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
    Inventors: Stephen John Atkinson, Emmanuel Hubert Demont, Lee Andrew Harrison, Thomas George Christopher Hayhow, Matthew J. Lindon, Alexander G. Preston, Jonathan Thomas Seal, Ian David Wall, Robert J. Watson, James Michael Woolven
  • Publication number: 20190331462
    Abstract: An armor system for protecting vehicles and other equipment against projectiles and similar threats. A track is mounted on the equipment, and an upper sled and lower sled are moveably attached to the track. An armor panel is pivotally attached to one sled and is pivotally attached with arms to the other sled. The two sleds are independently actuated along the track, such that their relative positions determine both the translational and rotational position of the armor panel. The armor panel can be quickly rotated from an undeployed position against the vehicle through a desired arc outward from the vehicle, which increases the edge-on or nearly edge-on presentation of the armor panel to the projectile.
    Type: Application
    Filed: April 26, 2018
    Publication date: October 31, 2019
    Inventors: James D. Walker, Daniel J. Pomerening, Kristopher C. Kozak, Nicholas J. Mueschke, Isaias S. Chocron, Gregory N. Wattis, Jesse A. Beavers, Oliver P. Harrison, Stephan J. Lemmer, Neal A. Seegmiller
  • Patent number: 10370356
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: August 6, 2019
    Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Stephen John Atkinson, Emmanuel Hubert Demont, Lee Andrew Harrison, Thomas George Christopher Hayhow, David House, Matthew J. Lindon, Alexander G. Preston, Jonathan Thomas Seal, Ian David Wall, Robert J. Watson, James Michael Woolven
  • Publication number: 20190202786
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: May 22, 2017
    Publication date: July 4, 2019
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Etienne LEVERNIER, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • Publication number: 20190151279
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: April 5, 2017
    Publication date: May 23, 2019
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • Patent number: 9315595
    Abstract: Disclosed is a method of preparing terminally functionalized telechelic polymers using a cationic living polymer product or a terminal tert-chloride chain end of a carbocationic quasiliving polymer product, which comprises quenching the polymer product with a functionalized N-substituted pyrrole to thereby introduce the functionalized N-substituted pyrrole at the terminal reactive polymer chain end(s). A method is also disclosed whereby the N-substituent may be derivatized to a basic amine containing functional group. Also disclosed are the terminal functionalized polyisobuyl N-substituted pyrrole compounds where the polyisobutyl group is substituted at the 2 and 3 position of the N-substituted pyrrole.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: April 19, 2016
    Assignees: Chevron Oronite Company LLC, The University of Southern Mississippi
    Inventors: Robson F. Storey, Casey D. Stokes, James J. Harrison, Nemesio Martinez-Castro
  • Publication number: 20160032041
    Abstract: Copolymers made with allyl-terminated polyolefins and unsaturated acidic reactants, dispersants using same, and methods of making same are provided. Under one aspect, a copolymer of an unsaturated acidic reactant and high molecular weight polyolefin, wherein the polyolefin comprises an allyl-terminated polymeric product, is provided. The allyl-terminated polymeric product is formed, e.g., by forming a quasi-living tert-halide terminated polyolefin under suitable quasi-living conditions, and contacting the tert-halide terminated polyolefin with an allylsilane compound and a Lewis acid. In some embodiments, the allylsilane compound includes allyltrimethylsilane.
    Type: Application
    Filed: October 14, 2015
    Publication date: February 4, 2016
    Inventors: James J. Harrison, Casey D. Stokes
  • Patent number: 8859473
    Abstract: An oil-soluble lubricating oil additive composition prepared by the process which comprises reacting (A) reacting a copolymer of an (i) an unsaturated acidic reagent; and (ii) a mono-olefin, with at least one linking hydrocarbyl di-primary amine, thereby producing a hybrid succinic anhydride copolymer having from about 10% to about 90% unreacted anhydride groups; and subsequently (B) reacting the hybrid succinic anhydride copolymer with a second amine compound, thereby producing the succinimide; and (C) reacting the succinimide with at least one post-treating agent selected from a cyclic carbonate, a linear mono-carbonate, a linear poly-carbonate, an aromatic polycarboxylic acid, an aromatic polycarboxylic anhydride, an aromatic polycarboxylic acid ester, or mixtures thereof.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: October 14, 2014
    Assignee: Chevron Oronite Company LLC
    Inventors: James J. Harrison, Mitra Hosseini
  • Patent number: 8748359
    Abstract: An oil-soluble lubricating oil additive composition prepared by the process which comprises reacting (A) reacting a copolymer of an (i) an unsaturated acidic reagent; and (ii) a mono-olefin, with at least one linking hydrocarbyl di-primary amine, thereby producing a hybrid succinic anhydride copolymer having from about 10% to about 90% unreacted anhydride groups; and subsequently (B) reacting the hybrid succinic anhydride copolymer with a second amine compound, thereby producing the succinimide; and (C) reacting the succinimide with at least one post-treating agent selected from a cyclic carbonate, a linear mono-carbonate, a linear poly-carbonate, an aromatic polycarboxylic acid, an aromatic polycarboxylic anhydride, an aromatic polycarboxylic acid ester, or mixtures thereof.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: June 10, 2014
    Assignee: Chevron Oronite Company LLC
    Inventors: James J. Harrison, Mitra Hosseini
  • Patent number: 8722927
    Abstract: The present invention is directed to Mannich condensation product sequestering agents or mixtures of Mannich condensation product sequestering agents for use in fuels and lubricating oils. The present invention is also directed to a process for preparing the Mannich condensation product sequestering agents. The present invention is also directed to a product formed by combining, under reaction conditions, a polyisobutyl-substituted hydroxyaromatic compound, an aldehyde, an amino acid or ester thereof, and an alkali metal base to form the Mannich condensation product sequestering agent. The present invention is also directed to a lubricating oil composition, a lubricating oil concentrate, a fuel composition, and a fuel concentrate having the Mannich condensation product sequestering agents of the present invention.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: May 13, 2014
    Assignee: Chevron Oronite Company LLC
    Inventors: James J. Harrison, Kenneth D. Nelson
  • Publication number: 20140031497
    Abstract: Disclosed is a method of preparing terminally functionalized telechelic polymers using a cationic living polymer product or a terminal tert-chloride chain end of a carbocationic quasiliving polymer product, which comprises quenching the polymer product with a functionalized N-substituted pyrrole to thereby introduce the functionalized N-substituted pyrrole at the terminal reactive polymer chain end(s). A method is also disclosed whereby the N-substituent may be derivatized to a basic amine containing functional group. Also disclosed are the terminal functionalized polyisobuyl N-substituted pyrrole compounds where the polyisobutyl group is substituted at the 2 and 3 position of the N-substituted pyrrole.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 30, 2014
    Applicants: The University of Southern Mississippi, Chevron Oronite Company LLC
    Inventors: Robson F. Storey, Casey D. Stokes, James J. Harrison, Nemesio Martinez-Castro
  • Publication number: 20130345104
    Abstract: The present invention provides for polyisobutenyl sulfonates, methods for preparing them, and composition employing them; wherein said polyisobutenyl sulfonates have improved low temperature and high temperature viscometric properties. The polyisobutenyl sulfonates are prepared by sulfonating polyisobutene and reacting the polyisobutenyl sulfonate with an alkali metal or alkaline earth metal, wherein the polyisobutene is characterized by having at least 90 mole percent methyl-vinylidene, a number average molecular weight of about 350 to 5,000, and a ratio of weight average molecular weight to number average molecular weight Mw/Mn of from about 1.01 to about 1.4.
    Type: Application
    Filed: December 5, 2012
    Publication date: December 26, 2013
    Applicant: Chevron Oronite Company LLC
    Inventor: James J. Harrison
  • Publication number: 20130298451
    Abstract: The present invention is directed to Mannich condensation product sequestering agents or mixtures of Mannich condensation product sequestering agents for use in fuels and lubricating oils. The present invention is also directed to a process for preparing the Mannich condensation product sequestering agents. The present invention is also directed to a product formed by combining, under reaction conditions, a polyisobutyl-substituted hydroxyaromatic compound, an aldehyde, an amino acid or ester thereof, and an alkali metal base to form the Mannich condensation product sequestering agent. The present invention is also directed to a lubricating oil composition, a lubricating oil concentrate, a fuel composition, and a fuel concentrate having the Mannich condensation product sequestering agents of the present invention.
    Type: Application
    Filed: April 12, 2013
    Publication date: November 14, 2013
    Applicant: Chevron Oronite Company LLC
    Inventors: James J. Harrison, Kenneth D. Nelson
  • Publication number: 20130303416
    Abstract: The present invention is directed to Mannich condensation product sequestering agents or mixtures of Mannich condensation product sequestering agents for use in fuels and lubricating oils. The present invention is also directed to a process for preparing the Mannich condensation product sequestering agents. The present invention is also directed to a product formed by combining, under reaction conditions, a polyisobutyl-substituted hydroxyaromatic compound, an aldehyde, an amino acid or ester thereof, and an alkali metal base to form the Mannich condensation product sequestering agent. The present invention is also directed to a lubricating oil composition, a lubricating oil concentrate, a fuel composition, and a fuel concentrate having the Mannich condensation product sequestering agents of the present invention.
    Type: Application
    Filed: April 12, 2013
    Publication date: November 14, 2013
    Applicant: Chevron Oronite Company LLC
    Inventors: James J. Harrison, Kenneth D. Nelson
  • Patent number: 8552122
    Abstract: Disclosed is a method of preparing terminally functionalized telechelic polymers using a cationic living polymer product or a terminal tert-chloride chain end of a carbocationic quasiliving polymer product, which comprises quenching the polymer product with a functionalized N-substituted pyrrole to thereby introduce the functionalized N-substituted pyrrole at the terminal reactive polymer chain end(s). A method is also disclosed whereby the N-substituent may be derivatized to a basic amine containing functional group. Also disclosed are the terminal functionalized polyisobuyl N-substituted pyrrole compounds where the polyisobutyl group is substituted at the 2 and 3 position of the N-substituted pyrrole.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: October 8, 2013
    Assignees: The University of Southern Mississippi, Chevron Oronite Company LLC
    Inventors: Robson F. Storey, Casey D. Stokes, James J. Harrison, Nemesio Martinez-Castro