Patents by Inventor James J. Hogan

James J. Hogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020038015
    Abstract: Hybridization assay probes and accessory oligonucleotides for detecting ribosomal nucleic acids from Candida albicans and/or Candida dubliniensis.
    Type: Application
    Filed: May 1, 2001
    Publication date: March 28, 2002
    Inventors: Curt L. Milliman, Gary G. Bee, James J. Hogan
  • Patent number: 6326486
    Abstract: Polynucleotides useful for specifically detecting bacteria in the family Enterobacteriaceae. Probes and accessory “helper oligonucleotides” are disclosed for use in hybridizing the rRNA and rDNA of Enterobacteriaceae without substantially cross-hybridizing with the rRNA or rDNA of numerous other bacterial and fungal species.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: December 4, 2001
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Patricia Gordon
  • Patent number: 6235484
    Abstract: Polynucleotide probes and accessory helper oligonucleotides useful for detecting the subset of High (G+C) subset of Gram-positive bacteria known as the “Actinomycetes.” The hybridization probes are highly specific for the Actinomycetes and do not cross-hybridize with the rRNA or rDNA of numerous other bacterial and fungal species.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: May 22, 2001
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Patricia Gordon
  • Patent number: 6093538
    Abstract: Hybridization assay probes are described which are able to distinguish Ureaplasma and known strains or serotypes of the species Ureaplasma urealyticum found in humans from other related organisms.
    Type: Grant
    Filed: August 18, 1993
    Date of Patent: July 25, 2000
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Diane L. McAllister, Patricia Gordon, Philip W. Hammond
  • Patent number: 6074826
    Abstract: The present invention discloses hybridization assay probes, amplification primers, nucleic acid compositions and methods useful for detecting Borrelia nucleic acids. Hybridization assay probes and amplification primers that selectively detect Lyme disease-associated Borrelia and distinguish those Borrelia from Borrelia hermsii are disclosed. Other hybridization probes selectively detect Borrelia hermsii and not Lyme disease-associated Borrelia are also described.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: June 13, 2000
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Yeasing Yang, Nick Carter
  • Patent number: 6028187
    Abstract: Hybridization assay probes specific for Listeria monocytogenes and no other Listeria species.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 22, 2000
    Assignee: Gen-Probe Incorporated
    Inventor: James J. Hogan
  • Patent number: 5681698
    Abstract: This invention discloses hybridization assay probes for Mycobacterium kansasii comprised of an oligonucleotide of about 18 nucleotides. These probes hybridize to a variable region of the 23S rRNA gene of Mycobacterium kansasii. The oligonucleotide probes are complementary to the rRNA variable region of the rRNA gene. Such probe specificity offers a rapid, non-subjective method of identification and quantitation of a bacterial colony for the presence of selected rRNA sequences capable of distinguishing all strains of Mycobacterium kansasii.
    Type: Grant
    Filed: January 5, 1994
    Date of Patent: October 28, 1997
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Philip W. Hammond
  • Patent number: 5541308
    Abstract: A method for preparing probes, as well as several probes for use in qualitative or quantitative hybridization assays are disclosed. The method comprises constructing an oligonucleotide that is sufficiently complementary to hybridize to a region of rRNA selected to be unique to a non-viral organism or group of non-viral organisms sought to be detected, said region of rRNA being selected by comparing one or more variable region rRNA sequences of said non-viral organism or group of non-viral organisms with one or more variable region rRNA sequences from one or more non-viral organisms sought to be distinguished. Hybridization assay probes for Mycobacterium avium, Mycobacterium intracellulare, the Mycobacterium tuberculosis-complex bacteria, Mycoplasma pneumoniae, Legionella, Salmonella, Chlamydia trachomatis, Campylobacter, Proteus mirabilis, Enterococcus, Enterobacter cloacae, E. coli, Pseudomonas group I, Neisseria gonorrhoeae, bacteria, and fungi also are disclosed.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: July 30, 1996
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Richard D. Smith, Jo A. Kop, Sherrol H. McDonough
  • Patent number: 5451503
    Abstract: Nucleic acid hybridization probes having at least one nucleic acid strand which has at least two separate target specific regions that hybridize to a target nucleic acid sequence, and at least two distinct arm regions that do not hybridize with the target nucleic acid but possess complementary regions that are capable of hybridizing with one another. These regions are designed such that, under appropriate hybridization conditions, the complementary arm regions will not hybridize to one another in the absence of the target nucleic acid; but, in the presence of target nucleic acid the target-specific regions of the probe will anneal to the target nucleic acid, and the complementary arm regions will anneal to one another, thereby forming a branched nucleic acid structure.
    Type: Grant
    Filed: June 7, 1994
    Date of Patent: September 19, 1995
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Lyle J. Arnold, Jr., Norman C. Nelson, Robert Bezverkov
  • Patent number: 5424413
    Abstract: Nucleic acid hybridization probes having at least one nucleic acid strand which has at least two separate target specific regions that hybridize to a target nucleic acid sequence, and at least two distinct arm regions that do not hybridize with the target nucleic acid but possess complementary regions that are capable of hybridizing with one another. These regions are designed such that, under appropriate hybridization conditions, the complementary arm regions will not hybridize to one another in the absence of the target nucleic acid; but, in the presence of target nucleic acid the target-specific regions of the probe will anneal to the target nucleic acid, and the complementary arm regions will anneal to one another, thereby forming a branched nucleic acid structure.
    Type: Grant
    Filed: September 4, 1992
    Date of Patent: June 13, 1995
    Assignee: Gen-Probe Incorporated
    Inventors: James J. Hogan, Lyle J. Arnold, Jr., Norman C. Nelson, Robert Bezverkov
  • Patent number: 5216143
    Abstract: Hybridization assay probes specific for Mycobacterium gordonae and no other Mycobacterium species.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: June 1, 1993
    Assignee: Gen-Probe Products Company
    Inventors: James J. Hogan, Philip W. Hammond
  • Patent number: 5030557
    Abstract: The binding of a nucleic acid probe with its complementary sequence in a targeted, single stranded nucleic acid is affected by the secondary and tertiary structure of the target nucleic acid. The rate and extent of hybridization of the probe with the targeted nucleic acid can be increased by the use of "helper" oligonucleotides. Helper oligonucleotides are selected to bind to the target nucleic acid and impose a different secondary and tertiary structure on the target to facilitate the binding of the probe to the target. The resulting hybrid of probe and target nucleic acid also exhibits a higher T.sub.m than the hybrid which results from addition of the probe alone.
    Type: Grant
    Filed: November 24, 1987
    Date of Patent: July 9, 1991
    Assignee: ML Technology Venture
    Inventors: James J. Hogan, Curt L. Milliman
  • Patent number: 4244029
    Abstract: A digital video correlator wherein a reference image and a live image are digitized and compared against each other in a shifting network to determine the correlation or degrees thereof existing between the two images. Fundamentally, the invention includes a video digitizer which divides live and real images from various sources into picture elements and digitizes those elements to fixed voltage levels. The digitized live image is passed to a dynamic memory consisting of a plurality of interconnected shift registers while the digitized reference image is maintained within a first set of shift registers comprising a portion of a processor. A second set of shift registers within the processor maintain therein a mask function. Yet a third set of shift registers within the processor are interconnected in parallel to the dynamic memory to receive, under control of a clock, the digitized data of the live image.
    Type: Grant
    Filed: December 12, 1977
    Date of Patent: January 6, 1981
    Assignee: Goodyear Aerospace Corporation
    Inventors: James J. Hogan, Charles O. Lambert, Gene A. Wallace