Abstract: Mobile management method, system and client. Method includes receiving a DNS query for a host name from an application on client; retrieving reputation data associated with host name from a local cache on client; and determining a policy based on host name and the reputation data. Based on determined policy for the host name, blocking attempted network flows to a host corresponding to host name to produce blocked attempted network flows. Method also includes sending attempted network flow metadata related to the blocked attempted network flows to a collector on client; transmitting the attempted network flow metadata from the collector to a VPN server pool via a VPN tunnel; and producing an anomaly report from the transmitted attempted network flow metadata. The anomaly report includes at least one of anomalies, cohorts, trends, location boundaries, detected network security issues, detected compromised clients and/or optimized network usage.

Abstract: A footbed system (10) for footwear comprises an insole mechanism (14), a midsole mechanism (11), wherein the insole mechanism is positioned on the midsole mechanism, and the outsole mechanism (15) is positioned under the midsole mechanism. The insole mechanism comprises a footbed insole (1), a heel pad (2) and a forefoot pad (3). The footbed insole comprises a pad anatomically shaped to correspond to the sole of a human foot, wherein the heel pad is positioned in the hindfoot portion of the footbed insole, and the forefoot pad is positioned in the forefoot portion of the footbed insole. The outsole mechanism comprises an opening (15A) for exposing a natural gait line groove of the midsole mechanism.

Abstract: A footbed system (10) for footwear comprises an insole mechanism (14), a midsole mechanism (11), wherein the insole mechanism is positioned on the midsole mechanism, and the outsole mechanism (15) is positioned under the midsole mechanism. The insole mechanism comprises a footbed insole (1), a heel pad (2) and a forefoot pad (3). The footbed insole comprises a pad anatomically shaped to correspond to the sole of a human foot, wherein the heel pad is positioned in the hindfoot portion of the footbed insole, and the forefoot pad is positioned in the forefoot portion of the footbed insole. The outsole mechanism comprises an opening (15A) for exposing a natural gait line groove of the midsole mechanism.

Abstract: Method and medical devices for generating and stabilizing micro or nano bubbles, and systems and methods for therapeutic applications using the bubbles, is provided. Two novel bubble generating means are provided: in-line capillary tubes and mix chambers flow focusing, and cross flow bubble generation with optimized bubble detachment means. A method and medical device to stabilize bubble sizes and improve bubble size homogeneity through rectified diffusion is disclosed. A method and system to facilitate acoustic activation of therapeutic agents using ultrasound energy is provided.

Abstract: Method and medical devices for generating and stabilizing micro- or nano-bubbles, and systems and methods for therapeutic applications using the bubbles, are provided. The micro-bubbles may be used to enhance therapeutic benefits such as ultrasound-guided precision drug delivery and real-time verification, acoustic activation of large tumor masses, enhanced acoustic activation through longer retention of therapeutic agents at the point of interest, enhancement of high intensity focused ultrasound treatments, light activation of photodynamic drugs at a depth within a patient using extracorporeal light sources, probes, or sonoluminescence, and initiation of time reversal acoustics focused ultrasound to permit highly localized treatment.

Abstract: Medical apparatus and processes controllably generate medically useful micro or nano bubbles of medically desirable and controllably selectable size, size distribution, homogeneity and concentration (and/or other key bubble parameters) for patient infusion, and/or which may incorporate therapeutic or other agents for patient infusion and/or may be combined with therapeutic or other agents prior to infusion into patients. The bubble generation apparatus and processes controllably permit the adjustment and selection of key bubble parameters through bubble generation actuation and orientation techniques and through selection of bubble fluid compositions in order to facilitate medical research and/or to optimize treatment for imaging, therapy, sonoporation, inertial and non-inertial cavitation, and acoustic activation, among other medical uses. Disposable cartridges containing such bubbles are provided and may include means for patient infusion.

Abstract: In one embodiment, the present invention provides a method for forming battery tray for holding cylindrical cell batteries. The method includes forming a battery try including a base support having a generally flat bottom surface and multiple adjacent cylindrical cavities are formed within the base support, using a circle packing algorithm to form the cylindrical cavities. The adjacent cavities each have at least some interstitial cylindrical riser wall structures formed with a predetermined height to hold the cylindrical cell batteries. In another embodiment, the present invention allows for packing maximum energy density per layer. This allows lifetime and power output of a battery powered device to be optimized and/or increased.

Abstract: Medical apparatus and processes controllably generate medically useful micro or nano bubbles of medically desirable and controllably selectable size, size distribution, homogeneity and concentration (and/or other key bubble parameters) for patient infusion, and/or which may incorporate therapeutic or other agents for patient infusion and/or may be combined with therapeutic or other agents prior to infusion into patients. The bubble generation apparatus and processes controllably permit the adjustment and selection of key bubble parameters through bubble generation actuation and orientation techniques and through selection of bubble fluid compositions in order to facilitate medical research and/or to optimize treatment for imaging, therapy, sonoporation, inertial and non-inertial cavitation, and acoustic activation, among other medical uses. Disposable cartridges containing such bubbles are provided and may include means for patient infusion.

Abstract: A method and system for determining a rate of insurance for management liability coverage which determines a base premium, a limit/retention factor, shared limit credits, and other rating considerations. The limit/retention factor, shared limit credits, and rating considerations are applied to the base premium to ascertain a resultant premium. Another aspect of the disclosure provides a method for determining a shared limit credit when insured clients purchase multiple insurance coverages in a single policy or package of policies and subject to common limit of liability.

Abstract: A method and system for determining a rate of insurance for management liability coverage which determines a base premium, a limit/retention factor, shared limit credits, and other rating considerations. The limit/retention factor, shared limit credits, and rating considerations are applied to the base premium to ascertain a resultant premium. Another aspect of the disclosure provides a method for determining a shared limit credit when insured clients purchase multiple insurance coverages in a single policy or package of policies and subject to common limit of liability.

Abstract: Paste-extruded sulfonamide herbicide compositions having improved spray equipment clean-out properties are made by preparing a mixture comprising a sulfonamide herbicide free acid, at least about 50 equivalent % of an inorganic base relative to the sulfonamide herbicide free acid and sufficient water to form an extrudable past, extruding the mixture to form an extrudate, and drying the extrudate.

Abstract: Method and medical devices for generating and stabilizing micro- or nano-bubbles, and systems and methods for therapeutic applications using the bubbles, are provided. The micro-bubbles may be used to enhance therapeutic benefits such as ultrasound-guided precision drug delivery and real-time verification, acoustic activation of large tumour masses, enhanced acoustic activation through longer retention of therapeutic agents at the point of interest, enhancement of high intensity focused ultrasound treatments, light activation of photodynamic drugs at a depth within a patient using extracorporeal light sources, probes, or sonoluminescence, and initiation of time reversal acoustics focused ultrasound to permit highly localized treatment.

Abstract: An implantable device for attracting diseased cells or foreign substances circulating within bodily fluid channels is disclosed. The device comprises a frame, an attachment means for maintaining the frame in a localized position in a body vessel, and at least one attractant on the frame, where the attractant is capable of attracting a diseased cell or a foreign substance. The device may also include a therapeutic agent The device may be used for diagnosis, disease containment or treatment. The device may also be used for attracting and localized treatment of diseased cells and foreign substances.

Abstract: A method and medical device for generating transient bubbles is provided. Fluid is delivered under pressure through bubble generating means and thereby transient bubbles are generated. The bubbles are micro or nano sized. An ultrasonic source may be used to further vibrate the bubble generating means so as to adjust the size and size consistency of the bubbles. Infusion means may also be provided for infusing the bubbles in a patient. A therapeutic agent, in the form of or delivered in combination with, bubbles may be injected at the point of interest. An ultrasound pulse may additionally be provided to activate bubbles to enhance drug transport through tissues and across cell membranes. The device provides a means to locally generate transient bubbles, to facilitate acoustical activation of therapeutic agents, and the acoustic activation of bubbles infused within therapeutic agents, in order to enhance treatment efficacy.

Abstract: A process for separating (?)-?9-trans-tetrahydrocannabinol from a mixture of cannabinoids is disclosed. The process comprises at least one chromatographic step wherein a mobile phase passes trough a stationary phase. The stationary phase comprises a derivatised polysaccharide and the mobile phase comprises carbon dioxide.

Abstract: Medical apparatus and processes controllably generate medically useful micro or nano bubbles of medically desirable and controllably selectable size, size distribution, homogeneity and concentration (and/or other key bubble parameters) for patient infusion, and/or which may incorporate therapeutic or other agents for patient infusion and/or may be combined with therapeutic or other agents prior to infusion into patients. The bubble generation apparatus and processes controllably permit the adjustment and selection of key bubble parameters through bubble generation actuation and orientation techniques and through selection of bubble fluid compositions in order to facilitate medical research and/or to optimize treatment for imaging, therapy, sonoporation, inertial and non-inertial cavitation, and acoustic activation, among other medical uses. Disposable cartridges containing such bubbles are provided and may include means for patient infusion.

Abstract: A method and system for determining a rate of insurance for management liability coverage which determines a base premium, a limit/retention factor, shared limit credits, and other rating considerations. The limit/retention factor, shared limit credits, and rating considerations are applied to the base premium to ascertain a resultant premium. Another aspect of the disclosure provides a method for determining a shared limit credit when insured clients purchase multiple insurance coverages in a single policy or package of policies and subject to common limit of liability.

Abstract: A medical device having enhanced ultrasonic visibility is provided. The device permits localized drug delivery, probe positioning, fluid drainage, biopsy, or ultrasound pulse delivery, through the real-time ultrasound monitoring of the needle tip position within a patient. The device permits controlled dispersion of a drug into solid tissue, the lodging of particles into solid tissue, and drug delivery into specific blood vessels. As a needle is inserted, a fluid that contrasts echogenically with the organ environment is injected into the patient. The fluid travels a brief distance before being slowed and stopped by the patient's tissue and this fluid flow will be detectable by ultrasound. The needle position during insertion will be monitored using ultrasound until it is at the desired point of action.

Abstract: One embodiment of an cabinet according to the present invention comprises an inner cabinet having a plurality of inner walls that form an enclosure. A phase change material covers at least some of the plurality of inner walls. An outer cabinet is positioned around the inner cabinet and comprises a plurality of outer walls arranged such that there is a space between the inner and outer walls. A mechanism is included for drawing air from outside of the outer cabinet into the space between the inner and outer walls. The phase-change material is arranged to melt when exposed to heat energy to reduce heat transfer into the enclosure. The enclosure is particularly adapted for holding heat sensitive devices such as batteries with the cabinet controlling heat transfer during cyclic heat exposure.

Abstract: Electric apparatus having distinct electric terminals has an input power terminal of electrically insulating material, including a base of electric insulating material having a first electric terminal base portion and a second electric base portion spaced from that first electric base portion, and a barrier wall of insulating material on that base acting as an isolator between the first and second electric terminals on these base portions, and preferably also as a standoff for a protective cover. A plurality of electric fuse holders in that or other electric apparatus may be mounted in mutually spaced relationship, and a heat sink including a frame around that plurality of mutually spaced electric fuse holders is in heat-transfer relationship with these electric fuse holders, and includes a cross-piece between each adjacent pair of the mutually spaced electric fuse holders.