Patents by Inventor James M. Taylor

James M. Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10689399
    Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: June 23, 2020
    Assignee: Gilead Sciences, Inc.
    Inventors: Elizabeth M. Bacon, Zhenhong R. Cai, Xiaowu Chen, Jeromy J. Cottell, Manoj C. Desai, Mingzhe Ji, Haolun Jin, Scott E. Lazerwith, Michael R. Mish, Philip Anthony Morganelli, Hyung-Jung Pyun, James G. Taylor, Teresa Alejandra Trejo Martin
  • Publication number: 20200176138
    Abstract: A method and apparatus for modifying an existing nuclear reactor moveable in-core detector system to insert and withdraw target specimens from a reactor core during reactor operation without practically impeding the moveable in-core detector system's ability to obtain flux maps of the core throughout the reactor's operation. The apparatus provides a separate drive unit and delivery cable that is independent of the detector drive system, but uses most of the same core delivery conduits to access the core. A specimen holder is remotely detachable from the delivery cable when appropriately positioned and can be remotely reattached for withdrawal after a scheduled period of radiation.
    Type: Application
    Filed: February 3, 2020
    Publication date: June 4, 2020
    Applicant: Westinghouse Electric Company LLC
    Inventors: Michael D. HEIBEL, Luke D. CZERNIAK, Melissa M. HEAGY, Jorge V. CARVAJAL, Matthew D. MCARDLE, Jeffrey J. TAYLOR, James L. YANKEL
  • Publication number: 20200123172
    Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
    Type: Application
    Filed: December 17, 2019
    Publication date: April 23, 2020
    Inventors: Elizabeth M. Bacon, Gayatri Balan, Chien-Hung Chou, Christopher T. Clark, Jeromy J. Cottell, Musong Kim, Thorsten A. Kirschberg, John O. Link, Gary Phillips, Scott D. Schroeder, Neil H. Squires, Kirk L. Stevens, James G. Taylor, William J. Watkins, Nathan E. Wright, Sheila M. Zipfel
  • Publication number: 20200123132
    Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: May 23, 2019
    Publication date: April 23, 2020
    Inventors: Elizabeth M. Bacon, Jeromy J. Cottell, Ashley Anne Katana, Darryl Kato, Evan S. Krygowski, John O. Link, James G. Taylor, Chinh Tran, Teresa Alejandra Trejo Martin, Zheng-Yu Yang, Sheila Zipfel
  • Publication number: 20200079769
    Abstract: A compound of Formula (I): pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof are disclosed.
    Type: Application
    Filed: August 13, 2019
    Publication date: March 12, 2020
    Inventors: Stephen Ammann, Elizabeth M. Bacon, Gediminas Brizgys, Elbert Chin, Chienhung Chou, Jeromy J. Cottell, Marilyn Ndukwe, Marina Shatskikh, James G. Taylor, Nathan E. Wright, Zheng-Yu Yang, Sheila M. Zipfel
  • Publication number: 20200071333
    Abstract: A compound of Formula (I): pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof are disclosed.
    Type: Application
    Filed: August 13, 2019
    Publication date: March 5, 2020
    Inventors: Stephen Ammann, Elizabeth M. Bacon, Gediminas Brizgys, Elbert Chin, Chienhung Chou, Jeromy J. Cottell, Marilyn Ndukwe, James G. Taylor, Nathan E. Wright, Zheng-Yu Yang, Sheila M. Zipfel
  • Publication number: 20200071337
    Abstract: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: April 8, 2019
    Publication date: March 5, 2020
    Inventors: Elizabeth M. Bacon, Jeromy J. Cottell, Ashley Anne Katana, Darryl Kato, Evan S. Krygowski, John O. Link, James G. Taylor, Chinh Viet Tran, Teresa Alejandra Trejo Martin, Zheng-Yu Yang, Sheila Zipfel
  • Patent number: 10581492
    Abstract: Various embodiments for heat management around a phase delay coil in a probe are described. A guided surface waveguide probe may be at least partially housed or enclosed in a structure and configured to generate electrical energy in the form of a guided surface wave traveling along a terrestrial medium, where the guided surface waveguide probe comprises at least one electromagnetic coil encapsulated by an exterior of the structure. A cooling device may be provided and configured to manage heat in the structure by providing cold air between the at least one electromagnetic coil and the exterior of the structure.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: March 3, 2020
    Assignee: CPG TECHNOLOGIES, LLC
    Inventors: James F. Corum, Kenneth L. Corum, Christopher R. Lamon, James M. Salvitti, Jr., Robert S. Galloway, Jr., James T. Darnell, Fredrick A. Genz, Wes Pogorzelski, Michael P. Taylor, Philip V. Pesavento, Timothy J. Lougheed, Jr., Jerry A. Lomax
  • Publication number: 20200054558
    Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.
    Type: Application
    Filed: March 20, 2019
    Publication date: February 20, 2020
    Applicant: PARION SCIENCES, INC.
    Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
  • Publication number: 20200048261
    Abstract: A compound of Formula (I): pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof are disclosed.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Applicant: Gilead Sciences, Inc.
    Inventors: Stephen Ammann, Elizabeth M. Bacon, Gediminas Brizgys, Elbert Chin, Chienhung Chou, Jeromy J. Cottell, Marilyn Ndukwe, James G. Taylor, Nathan E. Wright, Zheng-Yu Yang, Sheila M. Zipfel
  • Publication number: 20200017510
    Abstract: A compound of Formula (I): pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof, wherein the variable substituents are disclosed herein.
    Type: Application
    Filed: July 11, 2019
    Publication date: January 16, 2020
    Inventors: Stephen Ammann, Elizabeth M. Bacon, Gediminas Brizgys, Elbert Chin, Chienhung Chou, Jeromy J. Cottell, Marilyn Ndukwe, James G. Taylor, Nathan E. Wright, Zheng-Yu Yang, Sheila M. Zipfel
  • Publication number: 20190329928
    Abstract: A method of manufacturing a coated paperboard container includes: providing a coated paperboard bottom blank, the coated paperboard bottom blank comprising a paperboard substrate and a first barrier coating layer on a first outermost surface of the paperboard substrate; heating the coated paperboard bottom blank; shaping the heated coated paperboard bottom blank, thereby forming a peripheral skirt portion about a periphery of a bottom wall portion of the coated paperboard bottom blank; and sealing a coated paperboard sidewall to the first barrier coating layer of the peripheral skirt portion.
    Type: Application
    Filed: April 23, 2019
    Publication date: October 31, 2019
    Inventors: Eric D. Linvill, Jiebin Pang, Natasha G. Melton, James M. Taylor, Steven Parker
  • Patent number: 10447342
    Abstract: Disclosed is a guided surface waveguide probe with a charge terminal that is elevated over a lossy conducting medium. A primary coil can be coupled to an excitation source within a substructure. A secondary coil can provide a voltage to the charge terminal with a phase delay (?) that matches a wave tilt angle (?) associated with a complex Brewster angle of incidence (?i,B) associated with the lossy conducting medium. The primary coil can be configured to inductively couple to the secondary coil.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: October 15, 2019
    Assignee: CPG Technologies, LLC
    Inventors: James F. Corum, Kenneth L. Corum, Christopher R. Lamon, James M. Salvitti, Jr., Robert S. Galloway, Jr., James T. Darnell, Fredrick A. Genz, Wes Pogorzelski, Michael P. Taylor, Philip V. Pesavento, Timothy J. Lougheed, Jr., Jerry A. Lomax
  • Patent number: 10443607
    Abstract: A blade for an axial flow machine having a pressure surface, suction surface and trailing edge. The blade has a cross-sectional aerofoil profile including: a region of maximum curvature corresponding to the trailing edge of the blade and defining a trailing edge radius of curvature r; a trailing edge region extending from the trailing edge and having a chordwise extent equal to curvature r's trailing edge radius; a taper region adjacent the trailing edge region, the taper region having a chordwise extent greater than the curvature r's trailing edge radius and no more than 15% of the blade's chord; a body region adjacent the taper region; a pressure surface boundary corresponding to the blade's pressure surface; and a suction surface boundary corresponding to the blade's suction surface. A thickness between the pressure and suction surface boundaries reduces within the taper region towards the trailing edge by at least 50%.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: October 15, 2019
    Assignee: ROLLS-ROYCE plc
    Inventors: William J Brown, Christopher R P Hall, Anthony M J Dickens, James V Taylor
  • Publication number: 20190276468
    Abstract: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: October 11, 2018
    Publication date: September 12, 2019
    Inventors: Elizabeth M. Bacon, Jeromy J. Cottell, Ashley Anne Katana, Darryl Kato, Evan S. Krygowski, John O. Link, James G. Taylor, Chinh Viet Tran, Teresa Alejandra Trejo Martin, Zheng-Yu Yang, Sheila M. Zipfel
  • Publication number: 20190262011
    Abstract: A cannulated retrograde reamer that is adjustable to create tunnels of multiple different diameters. The cannulated retrograde reamer substantially reduces the risk of tunnel malposition and/or misalignment, and can be adjusted to create a range of tunnel diameters, thereby allowing inventory levels to be reduced for a surgical case.
    Type: Application
    Filed: May 13, 2019
    Publication date: August 29, 2019
    Applicant: Smith & Nephew, Inc.
    Inventors: Steven Mark Bowman, James J. Kennedy, III, Sean M. Frick, Glenn Kenneth Trainer, Jon B. Taylor, David J. Callaghan
  • Publication number: 20190248807
    Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
    Type: Application
    Filed: April 23, 2019
    Publication date: August 15, 2019
    Applicant: Gilead Sciences, Inc.
    Inventors: Elizabeth M. Bacon, Gayatri Balan, Chienhung Chou, Christopher T. Clark, Jeromy J. Cottell, Musong Kim, Thorsten A. Kirschberg, John O. Link, Gary B. Phillips, Scott D. Schroeder, Neil H. Squires, Kirk L. Stevens, James G. Taylor, William J. Watkins, Nathan E. Wright, Sheila M. Zipfel
  • Patent number: 10365220
    Abstract: Raman spectra of cells, such as normal human T- and B-cells from peripheral blood or human tonsil and the corresponding transformed cells are obtained by optically trapping the cells and obtaining their Raman spectra. The trapped cells can be subjected to one, two, or more different excitation wavelengths, and each wavelength of the corresponding Raman spectra can be stored in a separate channel. In preferred embodiments, two spectra are subtracted from each other to give a difference spectrum and each channel is analyzed independently to characterize the trapped cell. Alternatively, the Raman spectrum can be subjected to Principal Component Analysis (PCA) in order to characterize the trapped cell. The trapped cell thus classified can be sorted, or further manipulated.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: July 30, 2019
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: James W. Chan, Thomas R. Huser, Stephen M. Lane, John C. Rutledge, Douglas S. Taylor, Theodore Zwerdling, Ronald Li
  • Patent number: 10357259
    Abstract: A cannulated retrograde reamer that is adjustable to create tunnels of multiple different diameters. The cannulated retrograde reamer substantially reduces the risk of tunnel malposition and/or misalignment, and can be adjusted to create a range of tunnel diameters, thereby allowing inventory levels to be reduced for a surgical case.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: July 23, 2019
    Assignee: Smith & Nephew, Inc.
    Inventors: Steven Mark Bowman, James J. Kennedy, III, Sean M. Frick, Glenn Kenneth Trainer, Jon B. Taylor, David J. Callaghan
  • Patent number: 10344019
    Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: July 9, 2019
    Assignee: Gilead Pharmasset LLC
    Inventors: Elizabeth M. Bacon, Jeromy J. Cottell, Ashley Anne Katana, Darryl Kato, Evan S. Krygowski, John O. Link, James G. Taylor, Chinh Tran, Teresa Alejandra Trejo Martin, Zheng-Yu Yang, Sheila M. Zipfel