Patents by Inventor James Metz

James Metz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130074848
    Abstract: An anti-obstructive airway dental orthotic is described. The orthotic includes a maxillary retainer and a mandibular retainer releasably attaching to a plurality of teeth of a wearer. The retainers are attached by at least one strut, either variable in length or of a plurality of lengths, which exert a forward force on the lower jaw, tending to advance the mandible relative to the maxilla. This advancement of the lower jaw promotes a less obstructed airway in the wearer, while fenestrations in the retainers may allow for greater comfort and tongue movement.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 28, 2013
    Inventor: James Metz
  • Publication number: 20120028205
    Abstract: A dental orthotic covering a plurality of teeth is provided for improving various obstructive syndromes of the human upper airway. The orthotic may be relatively thickened on the lingual side of the orthotic, compared to the facial or occlusal side; and in particular may relatively thickened in the more posterior aspects of the lingual side of the orthotic as compared to the more anterior aspects of the lingual side of the orthotic. The orthotic may be formed of one piece or two, and may be purely mandibular, or may be coupled to a maxillary orthotic. A method of progressive fitting of the orthotic for optimization of a patient's blood oxygen level is described.
    Type: Application
    Filed: July 30, 2010
    Publication date: February 2, 2012
    Inventor: James Metz
  • Publication number: 20090063182
    Abstract: The present invention provides a system for reconnecting individuals via a visual signal. The visual signal is used by a certain individual to indicate to another individual of interest to correspond with them at a certain pre-determined destination such as a business location or on-line via a computer network, such as the Internet or a destination website. Sending a visual signal to another individual indicates that a certain individual is interested in corresponding with the other individual for dating, friendship, or other social or professional networking.
    Type: Application
    Filed: September 2, 2008
    Publication date: March 5, 2009
    Inventors: Peter James Metz, Nadav Baron
  • Publication number: 20080050790
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 28, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080050791
    Abstract: Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.
    Type: Application
    Filed: July 23, 2007
    Publication date: February 28, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: Craig Weaver, Ross Zirkle, James Metz
  • Publication number: 20080044872
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080044874
    Abstract: Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.
    Type: Application
    Filed: July 23, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: Craig Weaver, Ross Zirkle, James Metz
  • Publication number: 20080044870
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080044873
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080044869
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080044868
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080044867
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 12, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, James Flatt, Jerry Kuner, William Barclay
  • Publication number: 20080044871
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 21, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080038794
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080038795
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080038378
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 12, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, James Flatt, Jerry Kuner, William Barclay
  • Publication number: 20080038799
    Abstract: Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.
    Type: Application
    Filed: July 23, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: Craig Weaver, Ross Zirkle, James Metz
  • Publication number: 20080038793
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 16, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, Craig Weaver, William Barclay, James Flatt
  • Publication number: 20080038798
    Abstract: Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.
    Type: Application
    Filed: July 23, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: Craig Weaver, Ross Zirkle, James Metz
  • Publication number: 20080038791
    Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
    Type: Application
    Filed: July 12, 2007
    Publication date: February 14, 2008
    Applicant: MARTEK BIOSCIENCES CORPORATION
    Inventors: James Metz, James Flatt, Jerry Kuner, William Barclay