Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A female electrical terminal is comprised of a contact body which is electrically conductive and at least partially bounds an interior volume. The doubly coiled contact spring is disposed in the interior volume. The spring is configured to have a first coil which defines a first helix having a central axis, and the spring is wound so that the central axis defines a second helix.

Abstract: A wireless remote-control transmitter includes means for entering an identification code so that only an authorized operator can use the device. Use as a keyless entry system provides the owner of a wireless receiver with an additional keypad-operated transmitter which may be vehicle mounted to perform some or all of the same functions as those available through an existing remote. In this embodiment, the keypad may be mounted behind a small section of the vehicle's window glass, with command inputs being sensed using electrical, magnetic, or optical detection techniques. To save on battery power, the system automatically powers down during periods of non-use, with some form of wake-up signal being used to enter operational modes requiring increased power consumption.

Abstract: A wireless remote-control transmitter includes means for entering an identification code so that only an authorized operator can use the device. Use as a keyless entry system provides the owner of a vehicle equipped with a wireless receiver with an additional keypad-operated transmitter which may be vehicle mounted to perform some or all of the same functions as those available through an existing remote. In this embodiment, the keypad may be mounted behind a small section of the vehicle's window glass, with command inputs being sensed using electrical, magnetic, or optical detection techniques. To save on battery power, the system automatically powers down during periods of nonuse, with some form of wake-up signal being used to enter operational modes requiring increased power consumption.

Abstract: A power distribution module is especially suited to vehicular applications. An input/output module port is adapted for connection to an external multiplexed communication path, with transceiver circuitry being operative to send and receive messages over the communication path in digital form. The module is flexible enough to support a standard or user-defined commination protocol. An input is adapted for connection to a source of power. A plurality of controllable power switches are used to selectively route power from the source to a plurality of power output ports each port being associated with one of the switches. Control circuitry, operatively connected to the transceiver circuitry and to each power switch, facilitates the sending and receiving of messages over the communication path and provides control signals to the switches in accordance with a message received.

Abstract: A wireless remote-control transmitter includes circuitry for entering an identification code so that only an authorized operator can use the device. Use as a keyless entry system provides the owner of a vehicle equipped with a wireless receiver with an additional keypad-operated transmitter which may be vehicle mounted to perform some or all of the same functions as those available through an existing remote. In this embodiment, the keypad may be mounted behind a small section of the vehicle's window glass, with command inputs being sensed using electrical, magnetic, or optical detection techniques. To save on battery power, the system automatically powers down during periods of non-use, use, with some form of wake-up signal being used to enter operational modes requiring increased power consumption.

Abstract: A combination motor brush support and electromagnetic suppression circuit comprises an assembly having a base which is affixable to a portion of a motor housing and which supports all components requiring precise mechanical alignment, including motor brushes, brush guides and brush springs. The base can also support the choke coils, and at least some of the capacitors of the noise suppression circuitry. The base includes a terminal support board affixed to, and projecting therefrom. The terminal support board has at least one of the capacitors of the noise suppression circuitry retained thereupon, and provides a set of motor contact terminals which are in electrical communication with the motor brushes supported on the base. The support member of the present invention functions as its own assembly tool for supporting and retaining the coils, capacitors, springs and the like.

Abstract: A terminal free electrical connector. The connector includes a housing having a plurality of apertures formed therein for the introduction of electrical leads. A wire frame fits into the housing and has a plurality of arrayed throughbores, into which the leads are inserted. The wire frame includes a slot which leaves a portion of each lead exposed. Electrical contact may thus be maintained between the exposed portions of the leads in the wire frame and either a mating electrical connector, or a flat contact surface. A method connecting electrical leads without the use of terminals is also disclosed.

Abstract: A low resistance current interrupter for detecting the occurrence of an unsafe condition and terminating power to an electrical circuit. The current interrupter comprises two in-line connectors having a gap formed therebetween. An electrically conductive pin is disposed in the gap for movement between a first, extended position, wherein the pin bridges the gap to establish electrical contact between the connectors, to a second, retracted position wherein electrical contact is broken. The device further includes means for sensing the occurrence of an unsafe condition and generating a signal indicative thereof, and an electromechanical means such as a solenoid which, upon receiving said electrical signal, is activated and causes the pin to move to the second position.

Abstract: A terminal free electrical connector. The connector includes a housing having a plurality of apertures formed therein for the introduction of electrical leads. A wire frame fits into the housing and has a plurality of arrayed throughbores, into which the leads are inserted. The wire frame includes a slot which leaves a portion of each lead exposed. Electrical contact may thus be maintained between the exposed portions of the leads in the wire frame and either a mating electrical connector, or a flat contact surface. A method connecting electrical leads without the use of terminals is also disclosed.

Abstract: An interface board for use, for example, in a motor vehicle to provide electrical interconnection between a plurality of electrical circuit control elements and a wiring harness. The board comprises a box structure including a plurality of circuit outlets on the upper face of the structure for plug in receipt of the electrical circuit control elements, a plurality of power outlets on a lower face of the structure for plug in receipt of electrical power input and output elements, and a series of electrical paths extending between the power outlets and a circuit control outlets. Each electrical path includes a first conductor extending generally parallel to the first and second faces and second conductors extending generally perpendicular to the first and second faces. The first conductors comprise flat ribbon elements and the second conductors comprise flat ribbon elements connected to the flat sides of the first conductors utilizing clinch joints.

Abstract: A low insertion force, high current connector terminal for vehicular applications. The terminal includes a receptacle connector member having means for varying the inside diameter of a socket thereof, and a pin connector member insertable therein. The receptacle connector member includes an outboardly displaceable resilient finger having a first stop surface engageable with a second stop surface formed on the pin connector member to prevent accidental axial displacement of the two connector members. A slot and mating guide are disposed on, respectively, the receptacle connector member and the pin connector member, said slot and guide serving as both a guide means when the members are connected and also as an indexing means to prevent the connection of two non-mating connector members.

Abstract: A terminal connector for retaining and supporting a female electrical terminal. The terminal connector is formed of an electrically insulating material and is configured such that the socket of the terminal and a portion of, but not the entire, edge of the terminal proximate said socket is exposed to allow access to the exposed portion by a probe to permit testing of the terminal.

Abstract: An environmentally sealed vehicular air bag sensor. The sensor employs a conventional ball and tube accelerometer which supplies an electrical signal when subjected to a deceleration of force equal to or greater than a preset limit. All of the electrical connections of the sensor are disposed in the interior thereof, and the interior is sealed from the operating environment of the vehicle, thus enhancing reliability and minimizing accidental damage thereto.

Abstract: A piezoelectric switch assembly and method of manufacture. A piezoelectric module is provided which is comprised of a carrier disk and a wafer of piezoelectric material disposed thereon, with electrical leads connected thereto. The piezoelectric module is disposed inside a hollow recess formed in a switch plug, with the periphery of the carrier disk supported on a rim thereof. A disk of compressible material is disposed between the body of the plug and the piezoelectric module. The switch plug is inserted into a hollow chamber formed in a switch insert, said switch insert having a pressure receiving front wall. A front member is provided which is formed with an aperture for receiving the switch insert. Pressure on the pressure receiving front wall of the socket causes deformation of the piezoelectric wafer to generate an electrical signal which is received by circuitry attached to the electrical leads to effect one or more preselected switch functions.

Abstract: A multiple terminal connector assembly comprises a male and female connector; each connector includes a plurality of sockets for receiving electrical terminal members and each further includes a wedge member for locking the terminals into the sockets. The connector assembly further includes a particularly configured sealing gasket associated with one of said connectors and a flange associated with the other of said connectors. The gasket and flange are operable to create a vertical seal which limits passage of moisture therepast. The connector assembly also includes a locking bolt for affixing the two connectors in mated engagement and an elastomeric seal extending along at least a portion of the length of the bolt.

Abstract: A package for electrical components provides for environmentally sealed, internal connection to the component. The package is operative to lock the electrical terminals of the component to terminals associated with external leads. The package further includes a grommet for sealing the interior thereof from ambient conditions.

Abstract: A tease-free switch includes a plurality of electrical terminals of planar configuration disposed in spaced apart relationship upon an electrically insulating base as well as a generally planar contact plate including at least two electrical contact regions thereupon. The plate is engaged by a push-button actuated stepping mechanism so as to be alternately rotated between a position where contact between particular of the terminals is alternately established and terminated. The switch is configured so that the contact plate is constantly biased into contact with the terminals and/or the insulating surface upon which they are disposed. In this manner partial activation of the switch will not alter the condition of the electrical contacts.

Abstract: An end cap for a fuel pump provides suppression of radio frequency noise generated by the motor of the pump. The end cap includes radio frequency suppression circuitry disposed therewithin and is configured so as to be a direct replacement for conventionally utilized end caps.

Abstract: A keyless marine access and engine control system. The system is caused to change from a dormant state to an enabled state when a sequence of actuation signals entered through a keypad matches data representing either one of two access sequences stored in the system's memory. When the system is in its enabled state, the system responds only to signals representing a keypad actuation exceeding a first predetermined time interval. These signals are used to crank, choke, and stop a marine vehicle engine. The secondary access sequence can be changed by a person who knows either the primary access sequence or the secondary access sequence, while the primary access sequence can be changed only by a person having knowledge of the present primary access sequence. In order to reprogram either access sequence, a programming button must be actuated for a predetermined time interval exceeding the first time interval. The system can be used with either a single or dual engine installation.