Abstract: A pipette and sealing pipette tip can include features for generating a secure mounting engagement between the pipette and pipette tip without the need for protrusions on the pipette tip used for providing an interference fit and avoiding the need for a separate air-tight seal directly between the piston and shaft of the pipette.

Abstract: A sub-1 ?L pipette having a small diameter metal tube that is concentrically located within the tip mounting shaft/portion of the pipette and extends from the distal end thereof by some predetermined distance so as to seal against the interior of a pipette tip that is installed to the tip mounting portion. The use of a small diameter metal tube and sealing of the metal tube against the inner surface of the pipette tip near a distal opening of the pipette tip allows for a minimal ullage volume.

Abstract: A pipette home position locating mechanism and a manual pipette equipped with such a home position locating mechanism. The home position locating mechanism is spring-biased but compressible in a proximal-to-distal direction. The spring preload force of the home position locating mechanism is selected to be greater than force of exerted by a stroke spring of the pipette to which the home position locating mechanism is attached while the stroke spring is at its blowout position, but less than the combined force exerted by the stroke spring at its blowout position and a blowout spring of the pipette in its preload position.

Abstract: A pipette home position locating mechanism and a manual pipette equipped with such a home position locating mechanism. The home position locating mechanism is spring-biased but compressible in a proximal-to-distal direction. The spring preload force of the home position locating mechanism is selected to be greater than force of exerted by a stroke spring of the pipette to which the home position locating mechanism is attached while the stroke spring is at its blowout position, but less than the combined force exerted by the stroke spring at its blowout position and a blowout spring of the pipette in its preload position.

Abstract: A sub-1 ?L pipette having a small diameter metal tube that is concentrically located within the tip mounting shaft/portion of the pipette and extends from the distal end thereof by some predetermined distance so as to seal against the interior of a pipette tip that is installed to the tip mounting portion. The use of a small diameter metal tube and sealing of the metal tube against the inner surface of the pipette tip near a distal opening of the pipette tip allows for a minimal ullage volume.

Abstract: A two-piece sealing pipette tip includes features to join the pieces in an air-tight manner without adhesive, and to seal the tip directly against the piston in an air displacement pipette, thereby avoiding the need for a piston seal within the pipette. This configuration reduces potential points of failure, allows the pipette-tip interface to be optimized, and improves liquid handling characteristics of the pipette.

Abstract: An air displacement pipette includes a segmented, stepped piston configured to displace additional air at a higher velocity during a blowout stroke, thereby enabling improved dispensing accuracy by more completely dislodging adhering liquid from a pipette tip following the preceding dispensing stroke.

Abstract: An air displacement pipette includes a segmented, stepped piston configured to displace additional air at a higher velocity during a blowout stroke, thereby enabling improved dispensing accuracy by more completely dislodging adhering liquid from a pipette tip following the preceding dispensing stroke.

Abstract: A sealing pipette tip includes features to seal the tip directly against the piston in an air displacement pipette, avoiding the need for a piston seal within the pipette. This configuration reduces potential points of failure, allows the pipette-tip interface to be optimized, and improves liquid handling characteristics of the pipette.

Abstract: A sealing pipette tip includes features to seal the tip directly against the piston in an air displacement pipette, avoiding the need for a piston seal within the pipette. This configuration reduces potential points of failure, allows the pipette-tip interface to be optimized, and improves liquid handling characteristics of the pipette.

Abstract: A volume adjustable pipette, comprising a plunger mounted for movement in a housing to and from a stop to aspirate a fluid into and dispense the fluid from a tip extending from the housing. The movement of the plunger is damped to reduce sudden plunger movements. An axially moveable volume setting member in the housing defines the stop and a volume setting for the pipette and is axially moveable by a user turnable volume setting member. Turning of the volume adjusting member also controls a coarse volume setting means and a fine volume setting means, the course volume setting means being responsive to a relatively small turning of the volume adjusting member for moving the volume setting member a relatively large axial distance and the fine volume setting means being responsive to a relatively large turning of the volume adjusting member for moving the volume setting member a relatively small axial distance.

Abstract: A sealing pipette tip includes features to seal the tip directly against the piston in an air displacement pipette, avoiding the need for a piston seal within the pipette. This configuration reduces potential points of failure, allows the pipette-tip interface to be optimized, and improves liquid handling characteristics of the pipette.

Abstract: A volume adjustable pipette, comprising a plunger mounted for movement in a housing to and from a stop to aspirate a fluid into and dispense the fluid from a tip extending from the housing. The movement of the plunger is damped to reduce sudden plunger movements. An axially moveable volume setting member in the housing defines the stop and a volume setting for the pipette and is axially moveable by a user turnable volume setting member. Turning of the volume adjusting member also controls a coarse volume setting means and a fine volume setting means, the course volume setting means being responsive to a relatively small turning of the volume adjusting member for moving the volume setting member a relatively large axial distance and the fine volume setting means being responsive to a relatively large turning of the volume adjusting member for moving the volume setting member a relatively small axial distance.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.

Abstract: A hybrid manual-electronic pipette combines a manually driven piston with real-time electronic measurement of liquid volume and piston displacement while compensating for both pipette-specific and pipette model-specific variations. The hybrid nature of the pipette facilitates increased accuracy and improved ease of use, and enables additional functionalities not practicable with traditional manual pipettes.