Abstract: According to at least one aspect of the present disclosure, an information-technology-design system is provided comprising at least one processor coupled to at least one memory, wherein the at least one processor is configured to receive information-technology-device information indicative of a plurality of information-technology devices in a space, the information-technology-device information including information-technology-device-location information, temperature information, and capture-index information, determine, based on the information-technology-device information, a containment type of the plurality of information-technology devices, select, based on the containment type, at least a portion of the capture-index information, determine, based on the information-technology-device-location information, the temperature information, and the at least the portion of the capture-index information, a respective cooling-performance assessment for each information-technology device of the plurality of informa

Abstract: Visual content to be displayed on a display of a user device is received. Obfuscation data for obscuring the visual content is generated and the obscured visual content is displayed on the display. A request to stop obscuring the visual content is transmitted from the user device to a remote device, in response to a drag gesture detected at the user device. As the drag gesture is performed, the obfuscation data is modified to reduce a level of obfuscation applied to the visual content before the request has been accepted, so that the visual content remains obscured but with a lower level of obfuscation. If the request is subsequently accepted at the remote device, the display is controlled to stop obscuring the visual content, thereby rendering the visual content fully visible on the display.

Abstract: There is provided a method of manufacturing a sealing member (42). The method comprises the steps of: (a) providing a mould having a cavity, a polymer injection port and a gas inlet port (38); (b) injecting a polymer and a blowing agent through the polymer injection port (28) into the cavity of the mould; and (c) introducing gas through the gas inlet port (38) into the cavity of the mould, to form a sealing member (42). The sealing member (42) comprises an internal chamber (44) at least partially bounded by a resiliently deformable enclosing wall formed of the polymer, the enclosing wall including an external surface, the external surface having a form that is determined by the cavity of the mould.

Abstract: The present disclosure provides novel combinations of muscle-specific enhancers and promoters useful for achieving high and persistent expression in muscle tissue or myocytes. The muscle-specific promoter elements are derived from a desmin promoter. The muscle-specific enhancer elements are derived from a desmin promoter and a muscle creatine kinase enhancer.

Abstract: A shield assembly is provided for an axle assembly of a machine. The machine includes a ground engaging device including a hub. The hub defines a cavity and an inboard opening to the cavity. The axle assembly includes a spindle, a final drive rotatably coupled to the spindle, and a gap disposed between the spindle and the final drive. The shield assembly has a shield body coupled to the axle assembly and disposed within the cavity of the ground engaging device. The shield body is located above portions of the spindle and the final drive, and extends over the gap.

Abstract: A lighting arrangement for a medical imaging system having a cylindrical wall that forms a tunnel that receives a patient to be scanned. The lighting arrangement includes a light transmitting section aligned on a longitudinal axis of the imaging system wherein the light transmitting section forms a part of the tunnel. The lighting arrangement also includes a reflector section that is radially outside the light transmitting section. In addition, the lighting arrangement includes at least one lighting device located between the reflector section and light transmitting section wherein the lighting device emits light that is reflected by the reflector section onto the light transmitting section and wherein the light is then transmitted through the light transmitting section and into the tunnel to circumferentially illuminate the tunnel.

Abstract: A packaged laundry product comprising packaging and perfume particles contained in said packaging; wherein the packaging comprises a cylindrical receptacle formed from a material comprising cellulosic fibres, wherein the receptacle comprises a mechanism for impeding a child's access to the container; and wherein the perfume particles comprise carrier material and perfume components.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: Compositions and methods are provided herein for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The compositions include fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap which is synthesized by the polymerase of the fusion protein and which becomes incorporated into the target DNA molecule.

Abstract: A method and apparatus for a commerce platform coordinating a purchase of a product sold by a merchant system through a third party application are described. The method may include receiving a notification from the third party application requesting to purchase a product from within the third party application, wherein the notification comprises an identifier for the product and an identifier for the merchant system that sells the product. The method may also include a product checkout interface having an appearance consistent with an appearance of a user interface of the third party application, and transmitting the product checkout interface generated by the commerce platform to a user device executing the third party application causing the third party application to render the product checkout interface within at least a portion of the user interface of the third party application.

Abstract: Compositions and methods are provided herein for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The compositions include fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap which is synthesized by the polymerase of the fusion protein and which becomes incorporated into the target DNA molecule.

Abstract: Compositions and methods are provided herein for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The compositions include fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap which is synthesized by the polymerase of the fusion protein and which becomes incoporated into the target DNA molecule.

Abstract: The present disclosure is directed to in grade light fixtures and recessed luminaires and subassemblies thereof, including, for example, a heat sink and pivot for a recessed luminaire, a gasket for the recessed luminaire, and an outer box and cover for installation of the recessed luminaire. The recessed luminaire comprises: a housing having an internal surface; and a light subassembly engaged with a thermally conductive body, the light subassembly having a first end and a second end, wherein the first end of the light subassembly is pivotally secured to a pivot arranged on, in, or proximate to the internal surface of the housing. The thermally conductive body is in thermal contact with the internal surface of the housing. The recessed luminaire further comprises a dehumidifier.

Abstract: A network, or part thereof for example a link, 1 is described. The network 1 is for data communication through a medium, preferably wherein the medium comprises and/or is, at least in part, a liquid medium LM. The network 1 comprises a set of transmitters 11, including a first transmitter 11A comprising a controller 110A, wherein the first transmitter 11A is configured to transmit a set of polarised optical signals S, including a first polarised optical signal S1 comprising first data D1 of set of data D. The network 1 comprises a set of receivers 12, including a first receiver 12A comprising a controller 120A, wherein the first receiver 12A is configured to receive the first polarised optical signal S1.

Abstract: The present disclosure relates to aerosol delivery devices. The aerosol delivery devices may include a reservoir containing a liquid aerosol precursor composition and an atomizer including an electrical resistance heating element and a nonfibrous liquid transport element having a microtextured surface adapted for surface wicking of the liquid aerosol precursor composition across the microtextured surface, the microtextured surface of the liquid transport element being in fluid communication with the reservoir and in fluid communication with the electric resistance heating element.

Abstract: An apparatus for applying a liquid matrix to a fiber tow includes a belt press arranged to receive the fiber tow and compress it between two moving belts and a matrix application roller arranged to receive liquid matrix and transfer it to the fiber. The apparatus also includes a second matrix application component arranged adjacent to the matrix application roller so as to form a first gap between the component and the matrix application roller. The matrix application roller is positioned adjacent to the belt press so as to form a second gap between the matrix application roller and a belt of the belt press; and wherein the second gap is larger than the first gap.

Abstract: A furnace structure includes a roof assembly of at least one layer of refractory material, and a metal plate that covers the at least one layer of refractory material and is configured to dissipate heat from the furnace structure; a plurality of sidewalls fixed to the roof, each of the sidewalls comprising refractory material at an interior surface and a metal wall plate at an outer surface; and a plurality of infrared emitters disposed in an opening in at least one of the refractory material of the sidewalls or the refractory material of the roof.

Abstract: A computer device, including at least a processor and a memory, can be configured to control process components on a computer device. An agent can intercept a request to instantiate a new process component in a user account of a logged-in user. The request can originate on the computing device from an instance of a particular process component amongst a set of process components. The user account can be assigned default user privileges by a privilege access management service. The agent can determine whether to permit the intercepted request. The agent can permit the intercepted request if the relationship is validated and if a trusted owner is identified amongst the set of identified owners.

Abstract: A lighting arrangement for a medical imaging system having a cylindrical wall that forms a tunnel that receives a patient to be scanned. The lighting arrangement includes a transparent wall section formed in the wall, wherein the transparent wall section extends along a transparent portion of a wall circumference. The imaging system also includes a lighting device located adjacent an outer surface of the transparent wall section. The lighting device extends along a device portion of a wall circumference corresponding to the transparent portion wherein light emitted by the lighting device is transmitted through the transparent wall section in a direction orthogonal to a longitudinal axis of the tunnel to circumferentially illuminate the tunnel. In addition, a system status is indicated by a color of light emitted by the LEDs. Further, light emitted by the lighting device varies in intensity to indicate a changing count rate.

Abstract: Methods and systems are disclosed for controlling device movement based on a movement command. Issues on accurately controlling movement of a device such as a programmable robot and rover are addressed by first determining a command type of the movement command, followed by determining specific types of controllers for a high-level controller and a low-level controller based on the determined command type. When the command type is a linear movement, a Proportional-Integral-Derivative (PID) controller is used at the high-level controller and a Proportional/Proportional-Integral (PPI) controller is used at the low-level controller to accurately control a target distance. When the command type is an angular movement, the PPI controller is used at the high-level controller and the PID controller is used at the low-level controller to accurate control the end-heading of the device.