Patents by Inventor James Zagzebski

James Zagzebski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8111810
    Abstract: A highly constrained image processing method is used to improve the quality, including spatial resolution and signal-to-noise ratio (SNR), of ultrasound image frames. Ultrasound image frames are accumulated to form a composite image that contains a priori information about the subject being imaged. This composite image is used in a HYPR processing method to improve the quality of the ultrasound image frame. For example, the SNR of the composite image is increased as a function of the number of ultrasound image frames used to produce it, and this increased SNR is passed on to each highly constrained image frame. Additionally, high spatial resolution ultrasound images are produced using an undersampled sampling density, and the quality of these images is restored to substantially the same level as a fully sampled image.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: February 7, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Zagzebski, Charles A. Mistretta
  • Patent number: 7601122
    Abstract: Ultrasonic strain measurements, which characterize the structure of tissue, may be obtained by combining multiple echo signals acquired at different compressions and at different angles. Such angular compounding may improve the quality of the elastic signal and provide at one time both an axial and lateral strain measurement.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: October 13, 2009
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Zagzebski, Tomy Varghese
  • Publication number: 20090129651
    Abstract: A highly constrained image processing method is used to improve the quality, including spatial resolution and signal-to-noise ratio (SNR), of ultrasound image frames. Ultrasound image frames are accumulated to form a composite image that contains a priori information about the subject being imaged. This composite image is used in a HYPR processing method to improve the quality of the ultrasound image frame. For example, the SNR of the composite image is increased as a function of the number of ultrasound image frames used to produce it, and this increased SNR is passed on to each highly constrained image frame. Additionally, high spatial resolution ultrasound images are produced using an undersampled sampling density, and the quality of these images is restored to substantially the same level as a fully sampled image.
    Type: Application
    Filed: November 13, 2008
    Publication date: May 21, 2009
    Inventors: James A. Zagzebski, Charles A. Mistretta
  • Patent number: 7331926
    Abstract: Ultrasonic signals obtained at a range of angles are fit to a material independent model to derive both axial and lateral strain and thus parameters dependent on lateral strain including Poisson's ratio and shear strain.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: February 19, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Tomy Varghese, Udomchai Techavipoo, Quan Chen, James A. Zagzebski
  • Patent number: 7297116
    Abstract: Elastography is used to examine soft tissue of the uterus to detect tumors and to evaluate the strength of the cervix of the uterus based on its elastographic properties.
    Type: Grant
    Filed: April 21, 2003
    Date of Patent: November 20, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Tomy Varghese, Mark Alan Kliewer, James A. Zagzebski
  • Patent number: 7275439
    Abstract: Parametric ultrasonic measurements which characterize the structure of tissue, using information from an ultrasonic signal beyond amplitude information, are obtained by combining multiple ultrasonic signals acquired at different angles, thereby reducing the variance of the calculations. Such angular compounding may be applied to detecting scatterer size, spacing, density, and attenuation.
    Type: Grant
    Filed: February 4, 2004
    Date of Patent: October 2, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Zagzebski, Tomy Varghese, Anthony L. Gerig
  • Patent number: 7166075
    Abstract: Elastographic images provide visualization in two or three dimensions of RF ablation lesions to guide in the ablation process. Compression may be applied using the RF probe. A similar technique may be applied to in vivo imaging of soft tissue without ablation.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: January 23, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Tomy Varghese, James A. Zagzebski, Udomchai Techavipoo, Quan Chen
  • Publication number: 20050165309
    Abstract: Ultrasonic signals obtained at a range of angles are fit to a material independent model to derive both axial and lateral strain and thus parameters dependent on lateral strain including Poisson's ratio and shear strain.
    Type: Application
    Filed: February 23, 2004
    Publication date: July 28, 2005
    Inventors: Tomy Varghese, Udomchai Techavipoo, Quan Chen, James Zagzebski
  • Publication number: 20040243001
    Abstract: Parametric ultrasonic measurements which characterize the structure of tissue, using information from an ultrasonic signal beyond amplitude information, are obtained by combining multiple ultrasonic signals acquired at different angles, thereby reducing the variance of the calculations. Such angular compounding may be applied to detecting scatterer size, spacing, density, and attenuation.
    Type: Application
    Filed: February 4, 2004
    Publication date: December 2, 2004
    Inventors: James A. Zagzebski, Tomy Varghese, Anthony L. Gerig
  • Publication number: 20040215075
    Abstract: Ultrasonic strain measurements, which characterize the structure of tissue, may be obtained by combining multiple echo signals acquired at different compressions and at different angles. Such angular compounding may improve the quality of the elastic signal and provide at one time both an axial and lateral strain measurement.
    Type: Application
    Filed: January 27, 2004
    Publication date: October 28, 2004
    Inventors: James A. Zagzebski, Tomy Varghese
  • Publication number: 20040210136
    Abstract: Elastography is used to examine soft tissue of the uterus to detect tumors and to evaluate the strength of the cervix of the uterus based on its elastographic properties.
    Type: Application
    Filed: April 21, 2003
    Publication date: October 21, 2004
    Inventors: Tomy Varghese, Mark Alan Kliewer, James A. Zagzebski
  • Patent number: 6749571
    Abstract: Elastographic imaging of heart tissue may be used to provide strain images by mapping strain magnitude to brightness and strain sign to hue and thus provide improved clinical indication of compression and distension of heart muscle. An areal cursor may be used to obtain quantitative measurements of strain at predetermined periods in the heart cycle. Multiple area measurements of strain may be combined to provide a quantitative index of cardiac health.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: June 15, 2004
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Tomy Varghese, Christian S. Breburda, James A. Zagzebski, Peter Samuel Rahko
  • Publication number: 20040059224
    Abstract: Elastographic imaging of heart tissue may be used to provide strain images by mapping strain magnitude to brightness and strain sign to hue and thus provide improved clinical indication of compression and distension of heart muscle. An areal cursor may be used to obtain quantitative measurements of strain at predetermined periods in the heart cycle. Multiple area measurements of strain may be combined to provide a quantitative index of cardiac health.
    Type: Application
    Filed: September 19, 2002
    Publication date: March 25, 2004
    Inventors: Tomy Varghese, Christian S. Breburda, James A. Zagzebski, Peter Samuel Rahko
  • Publication number: 20030171672
    Abstract: Elastographic images provide visualization in two or three dimensions of RF ablation lesions to guide in the ablation process. Compression may be applied using the RF probe. A similar technique may be applied to in vivo imaging of soft tissue without ablation.
    Type: Application
    Filed: March 8, 2002
    Publication date: September 11, 2003
    Inventors: Tomy Varghese, James A. Zagzebski, Udomchai Techavipoo, Quan Chen
  • Patent number: 5670719
    Abstract: In accordance with the present invention there is presented an automated system for testing the ability of clinical ultrasound scanners to detect focal lesions in human tissue. An ultrasound scanner phantom containing background material mimicking the ultrasonic characteristics of human tissue and coplanar spherical target lesions ultrasonically contrasting with the background material is scanned using the ultrasound scanner to be tested. Digitized images are made of the ultrasound scan of slices in the ultrasound phantom containing background material only and of slices on which the focal lesions are centered. A lesion signal to noise ratio (SNR).sub.L is then calculated at each defined pixel coordinate in the target lesion slice.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: September 23, 1997
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ernest L. Madsen, James A. Zagzebski, Gary R. Frank, Jason J. Rownd
  • Patent number: 5574212
    Abstract: In accordance with the present invention there is presented an automated system for testing the ability of clinical ultrasound scanners to detect focal lesions in human tissue. An ultrasound scanner phantom containing background material mimicking the ultrasonic characteristics of human tissue and coplanar spherical target lesions ultrasonically contrasting with the background material is scanned using the ultrasound scanner to be tested. Digitized images are made of the ultrasound scan of slices in the ultrasound phantom containing background material only and of slices on which the focal lesions are centered. A lesion signal to noise ratio (SNR).sub.L is then calculated at each defined pixel coordinate in the target lesion slice.
    Type: Grant
    Filed: June 14, 1995
    Date of Patent: November 12, 1996
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ernest L. Madsen, James A. Zagzebski, Gary R. Frank, Jason J. Rownd
  • Patent number: 4843866
    Abstract: An ultrasound phantom for use with an ultrasound scanner. The ultrasound phantom includes a container having a bottom and walls, margins of the walls remote from the bottom defining a window, which is closed by an ultrasound-transmitting window cover. A phantom body is contained within the container and includes a matrix made of a matrix material exhibiting a matrix ultrasonic speed, specific gravity, attenuation coefficient, and backscatter coefficient. The phantom body further includes a multiplicity of scattering particles spaced sufficiently close to each other that the scanner is incapable of resolving individual scattering particles and testing spheres having a testing sphere ultrasonic speed, specific gravity, attenuation coefficient, and backscatter coefficient, at least one of which is different from the corresponding matrix ultrasonic speed, specific gravity, attenuation coefficient, and backscatter coefficient. The testing spheres are located within the phantom body in a random array.
    Type: Grant
    Filed: February 16, 1988
    Date of Patent: July 4, 1989
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ernest L. Madsen, James A. Zagzebski, Gary R. Frank
  • Patent number: 4277367
    Abstract: Tissue mimicking material for use in ultrasound phantoms formulated as a uniform suspension of solid particles of graphite, talc, pumice, polyethylene microspheres, or liquid particles of vegetable oils, kerosine, or combinations thereof described as scatterers in a congealed gelatin-water-alcohol-preservative matrix; containing detergents to create the liquid particles.
    Type: Grant
    Filed: October 23, 1978
    Date of Patent: July 7, 1981
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ernest L. Madsen, James A. Zagzebski, Richard A. Banjavic, Michele M. Burlew