Patents by Inventor Jan Thurin

Jan Thurin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Matrix with immunomodulating activity
    Patent number: 5679354
    Abstract: The invention claims an iscom matrix which is not a lipid vesicle comprising at least one lipid and at least one saponim but no intentional antigenic determinants and optionally also adjuvants for use as an immunomodulating agent, medicines, vaccines, kits containing the matrix and new saponins, and a process for preparing the new saponins. The invention also concerns a process for preparing the matrix characterized in that at least one sterol is solubilized in a solvent or detergent, the saponin or saponins are added, the other adjuvants and lipids are optionally also added, whereafter the organic solvent or the detergent may be removed for example with dialysis, ultra filtration, gel filtration or electrophoresis. The sterol and saponin might also be solubilized in the lipids and/or adjuvants.
    Type: Grant
    Filed: May 21, 1991
    Date of Patent: October 21, 1997
    Inventors: Bror Morein, Karin Lovgren, Kristian Dalsgaard, Jan Thurin, Bo Sundquist
  • Monoclonal antibodies against melanoma-associated antigens and hybrid cell lines producing these antibodies
    Patent number: 4849509
    Abstract: The present invention is directed to monoclonal antibodies, and hybridomas which produce them, which are reactive with ganglioside antigens GD2 and GD3 and are essentially non-reactive with other ganglioside antigens. The invention further relates to methods of using these antibodies.
    Type: Grant
    Filed: February 20, 1987
    Date of Patent: July 18, 1989
    Assignee: The Wistar Institute
    Inventors: Jan Thurin, Hilary Koprowski, Meenhard Herlyn, Zenon Steplewski
  • Monoclonal antibodies for detection of an H (O) blood group antigen
    Patent number: 4678747
    Abstract: Monoclonal antibodies recognizing the difucosyl-type-2-H antigen on human cells and a method of producing said antibodies are disclosed. The monoclonal antibodies are useful in blood typing and in diagnosis of blood disorders and malignancies involving loss or gain of this H antigen.
    Type: Grant
    Filed: February 28, 1983
    Date of Patent: July 7, 1987
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Kenneth O. Lloyd, Lloyd J. Old, Karl-Anders Karlsson, Goran Larson, Nicklas Stromberg, Jan Thurin, Bernd R. Anger, Herbert F. Oettgen