Patents by Inventor Janet A. Rice

Janet A. Rice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090317891
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
    Type: Application
    Filed: July 30, 2009
    Publication date: December 24, 2009
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du PONT de NEMOURS and COMPANY
    Inventors: Andre Abad, Ronald D. Flannagan, Rafael Hermann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, James F. Wong, Cao-Guo Yu
  • Patent number: 7629449
    Abstract: In particular aspects of the invention, nucleic acid molecules encoding novel proteases identified in the midgut of Diabrotica virgfera virgfera (i.e., western corn rootworm) are provided. The nucleotide sequences encode novel cysteine proteases that belong to the cathepsin L-like subfamily of proteases. Variants and fragments of the nucleotide sequences that encode polypeptide sequences that possess proteolytic activity are further disclosed. Methods of using the nucleic acid sequences that encode novel proteases to protect a plant from an insect pest are provided. Particular embodiments also provide vectors, expression cassettes and transformed host cells comprising a protease nucleic acid of the invention.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: December 8, 2009
    Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Andre R. Abad, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, James F. Wong, Cao-Guo Yu
  • Publication number: 20090265818
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity).
    Type: Application
    Filed: January 9, 2009
    Publication date: October 22, 2009
    Applicants: Pioneer Hi-Bred International, Inc., E.I. Du Pont de Nemours and Company
    Inventors: Rafael Herrmann, Michael Lassner, Albert L. Lu, Mark Nelson, James K. Presnail, Janet A. Rice
  • Publication number: 20090264351
    Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from microbial fermentation broths. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the invention are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 22, 2009
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company, The Regents of the University of California
    Inventors: Daniel J. Altier, Glen Dahlbacka, Irina Ellanskaya, Natalia Ellanskaya, Rafael Herrmann, Jennie Hunter-Cevera, Billy F. McCutchen, James K. Presnail, Janet A. Rice, Eric Schepers, Carl R. Simmons, Tamas Torok, Nasser Yalpani
  • Publication number: 20090260106
    Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from microbial fermentation broths. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the invention are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 15, 2009
    Applicants: Pioneer Hi-Bred International, Inc., E.I. duPont de Nemours and Company, The Regents of the University of California
    Inventors: Daniel J. Altier, Glen Dahlbacka, Irina Ellenskaya, Natalia Ellanskaya, Rafael Herrmann, Jennie Hunter-Cevera, Billy F. McCutchen, James K. Presnail, Janet A. Rice, Eric Schepers, Carl R. Simmons, Tamas Torok, Nasser Yalpani
  • Patent number: 7601810
    Abstract: The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: October 13, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, Clement W. K. Waine
  • Publication number: 20090192117
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lygus genus, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides from specific polypeptide families as disclosed herein, and further provides target polynucleotides set forth in SEQ ID NOS:1-21 or active variants thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Lygus Hesperus.
    Type: Application
    Filed: January 9, 2009
    Publication date: July 30, 2009
    Applicants: Pioneer Hi-Bred International, Inc., E.I. Du Pont de Nemours and Company
    Inventors: Rafael Herrmann, Michael Lassner, Albert L. Lu, Mark E. Nelson, James K. Presnail, Janet A. Rice
  • Publication number: 20090192116
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Aphididae family, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides for specific protein classes and also target polynucleotides as set forth in SEQ ID NOS:1, 2, 3, 4, 5, 6, 7, 8, 9, 10 or active variants or fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Aphis glycines.
    Type: Application
    Filed: January 9, 2009
    Publication date: July 30, 2009
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Rafael Herrmann, Michael Lassner, Albert L. Lu, Mark Nelson, James K. Presnail, Janet A. Rice
  • Patent number: 7556936
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: July 7, 2009
    Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Andre R. Abad, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, James F. Wong, Cao-Guo Yu
  • Patent number: 7473821
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. Nucleic acid molecules encoding insect protoxins or insect toxins modified to comprise at least one proteolytic activation site that is sensitive to an insect gut protease are provided. Cleavage of a modified insect protoxin at the proteolytic activation site by an insect gut protease produces an active insect toxin in the gut of the insect pest. Cleavage of a modified insect toxin of the invention at a proteolytic activation site results in the production of an active insect toxin in the insect gut that displays improved pesticidal activity relative to the insect toxin that lacks the proteolytic activation site. Methods of using the modified insect protoxin and modified insect toxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: January 6, 2009
    Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Andre R. Abad, Gary C. Chun, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Janet A. Rice, Eric J. Schepers
  • Patent number: 7462760
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. The invention provides mutagenized nucleic acids that have been engineered to encode pesticidal polypeptides having increased resistance to proteolytic degradation by a plant protease. In particular, nucleic acid sequences encoding pesticidal polypeptides modified to comprise a proteolytic protection site that confers resistance to degradation or proteolytic inactivation by a plant protease are provided. Particular embodiments of the invention provide expression cassettes and transformed plants, plant cells, and seeds. These compositions find use in methods for protecting a plant from a pest.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: December 9, 2008
    Assignees: Pioneer Hi-Bred International, Inc., E.I. duPont de Nemours and Company
    Inventors: André Abad, Hua Dong, Rafael Herrmann, Albert Lu, Billy F. McCutchen, Janet A. Rice, Eric J. Schepers, James F. Wong
  • Patent number: 7442855
    Abstract: The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: October 28, 2008
    Assignee: E. I. du Pont De Nemours and Company
    Inventors: Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, Clement W. K. Waine
  • Publication number: 20080200415
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
    Type: Application
    Filed: November 14, 2007
    Publication date: August 21, 2008
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du PONT de NEMOURS and COMPANY
    Inventors: Andre Abad, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, James F. Wong, Cao-Guo Yu
  • Publication number: 20080124799
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
    Type: Application
    Filed: December 4, 2007
    Publication date: May 29, 2008
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du PONT de NEMOURS and COMPANY
    Inventors: Andre Abad, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, James F. Wong, Cao-Guo Yu
  • Patent number: 7378499
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. The invention provides mutagenized nucleic acids that have been engineered to encode pesticidal polypeptides having increased resistance to proteolytic degradation by a plant protease. In particular, nucleic acid sequences encoding pesticidal polypeptides modified to comprise a proteolytic protection site that confers resistance to degradation or proteolytic inactivation by a plant protease are provided. Particular embodiments of the invention provide pesticidal polypeptide compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds. These compositions find use in methods for controlling pests, especially plant pests. Novel plant proteases, sequences encoding these proteases, and methods for their use are also provided.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: May 27, 2008
    Assignees: Pioneer Hi-Bred International, Inc., E.I. Du Pont De Nemours and Company
    Inventors: André Abad, Hua Dong, Rafael Herrmann, Albert Lu, Billy F. McCutchen, Janet Rice, Eric Schepers, James Wong
  • Publication number: 20080108127
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
    Type: Application
    Filed: December 5, 2007
    Publication date: May 8, 2008
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du PONT de NEMOURS and COMPANY
    Inventors: Andre Abad, Ronald Flannagan, Rafael Hermann, Albert Lu, Billy McCutchen, James Presnail, Janet Rice, James Wong, Cao-Guo Yu
  • Patent number: 7339092
    Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: March 4, 2008
    Assignees: Pioneer Hi-Bred International, Inc., E.I. duPont deNemours & Company
    Inventors: Andre Abad, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Billy F. McCutchen, James K. Presnail, Janet A. Rice, James F. Wong, Cao-Guo Yu
  • Patent number: 7306946
    Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from microbial fermentation broths. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the invention are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: December 11, 2007
    Assignees: Pioneer Hi-Bred International, Inc., E.I. duPunt de Nemours and Company, The Regents of the University of California
    Inventors: Daniel J. Altier, Glen Dahlbacka, Natalia Ellanskaya, legal representative, Rafael Herrmann, Jennie Hunter-Cevera, Billy F. McCutchen, James K. Presnail, Janet A. Rice, Eric Schepers, Carl R. Simmons, Tamas Torok, Nasser Yalpani, Irina Ellanskaya, deceased
  • Publication number: 20070179284
    Abstract: The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
    Type: Application
    Filed: February 22, 2007
    Publication date: August 2, 2007
    Inventors: Rafael Herrmann, Albert Lu, Billy McCutchen, James Presnail, Janet Rice, Clement Waine
  • Publication number: 20070157338
    Abstract: The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
    Type: Application
    Filed: February 22, 2007
    Publication date: July 5, 2007
    Inventors: Rafael Herrmann, Albert Lu, Billy McCutchen, James Presnail, Janet Rice, Clement Waine