Patents by Inventor Jason G. Lewis
Jason G. Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150164905Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: ApplicationFiled: July 21, 2014Publication date: June 18, 2015Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Publication number: 20150157637Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: ApplicationFiled: July 11, 2014Publication date: June 11, 2015Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Publication number: 20150148311Abstract: Compounds having the following structure (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, R3, R4, R8, R9, R10, R11, R12, A1, A2, X, Y and Z are as defined herein. Uses of such compounds as TGR5 antagonists and for treatment of various indications, including Type II diabetes meletus are also provided.Type: ApplicationFiled: June 20, 2014Publication date: May 28, 2015Inventors: Jason G. Lewis, Nicholas Reich, Tao Chen, Jeffrey W. Jacobs, Dominique Charmot, Marc Navre, Patricia Finn, Christopher Carreras, Andrew Spencer
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Patent number: 8916569Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, A, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: GrantFiled: January 4, 2013Date of Patent: December 23, 2014Assignee: Ardelyx, Inc.Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Patent number: 8815908Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: GrantFiled: January 4, 2013Date of Patent: August 26, 2014Assignee: Ardelyx, Inc.Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Patent number: 8815910Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: GrantFiled: January 4, 2013Date of Patent: August 26, 2014Assignee: Ardelyx, Inc.Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Patent number: 8809339Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: GrantFiled: January 4, 2013Date of Patent: August 19, 2014Assignee: Ardelyx, Inc.Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Publication number: 20130336921Abstract: Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.Type: ApplicationFiled: January 4, 2013Publication date: December 19, 2013Applicant: ARDELYX, INC.Inventors: Jason G. Lewis, Jeffrey W. Jacobs, Nicholas Reich, Michael R. Leadbetter, Noah Bell, Han-Ting Chang, Tao Chen, Marc Navre, Dominique Charmot, Christopher Carreras, Eric Labonte
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Patent number: 7612059Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.Type: GrantFiled: June 13, 2005Date of Patent: November 3, 2009Assignee: Vicuron Pharmaceuticals, Inc.Inventors: Jeffrey Jacobs, Rakesh K Patel, Jason G Lewis, Dinesh V Patel, Zhengyu Yuan
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Publication number: 20090149509Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.Type: ApplicationFiled: December 3, 2008Publication date: June 11, 2009Applicant: VICURON PHARMACEUTICALS INC.Inventors: Jeffrey JACOBS, Rakesh K. JAIN, Jason G. LEWIS, Dinesh V. PATEL, Zhengyu YUAN
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Patent number: 7361743Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.Type: GrantFiled: August 31, 2005Date of Patent: April 22, 2008Assignee: Pfizer IncInventors: Jason G. Lewis, Sampath K Anandan, Hardwin O'Dowd, Mikhail F Gordeev, Liansheng Li
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Patent number: 7350923Abstract: In a computing device configured to be connected to a wireless network, a method of projecting an image via a projection device over the wireless network, is provided, wherein the projection device is connected to the wireless network via an image-rendering device configured to receive data over the wireless network. The method includes detecting the image-rendering device over the wireless network, presenting a display identifying the image-rendering device to a user, receiving selection of the image-rendering device by the user and sending data representing the image from the computing device to the image-rendering device over the wireless network for projection by the projection device.Type: GrantFiled: February 15, 2005Date of Patent: April 1, 2008Assignee: InFocus CorporationInventors: Jorell A. Olson, Robin F. Hoeye, Jason G. Lewis
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Patent number: 7256177Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.Type: GrantFiled: November 17, 2004Date of Patent: August 14, 2007Assignee: Vicuron Pharmaceuticals, Inc.Inventors: Jason G. Lewis, Sampath K. Anandan, Hardwin O'Dowd, Mikhail F. Gordeev
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Patent number: 7199106Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.Type: GrantFiled: June 17, 2004Date of Patent: April 3, 2007Assignee: Vicuron Pharmaceuticals, Inc.Inventors: Jason G. Lewis, Sampath-Kumar Anandan, Hardwin O'Dowd, Mikhail F. Gordeev
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Patent number: 7199105Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.Type: GrantFiled: February 11, 2004Date of Patent: April 3, 2007Assignee: Vicuron Pharmaceuticals, Inc.Inventors: Jason G. Lewis, Dinesh V. Patel, Sampath Kumar Anandan, Mikhail F. Gordeev
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Patent number: 7140731Abstract: An image-rendering device including a body, a connector configured to removably attach the body to a projection device, the connector movably coupled to the body such that the body is movable between at least a first position and a second position relative to the connector. The image-rendering device further includes an image receiver associated with the body, wherein the image receiver is configured to allow transfer of data representing an image to the image-rendering device. In some embodiments, the image receiver is a wireless receiver. The wireless receiver may be an integrated wireless network card or a removable wireless network card.Type: GrantFiled: March 15, 2006Date of Patent: November 28, 2006Assignee: InFocus CorporationInventors: Jorell A. Olson, Robin F. Hoeye, Jason G. Lewis
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Patent number: 7044605Abstract: An image-rendering device including a body, a connector movably coupled to the body, wherein the connector is configured to electrically and structurally couple the body to the projection device such that the body is movable relative to the connector, and an image receiver associated with the body is provided. The image receiver is adapted to alternatively receive first and second interchangeable data transfer devices, wherein each interchangeable data transfer device is configured to allow transfer of data representing an image to the image-rendering device. The image-rendering device also includes a processor and memory, wherein the memory includes a set of instructions executable by the processor to render the image from the data and to provide the image to the projection device.Type: GrantFiled: June 2, 2003Date of Patent: May 16, 2006Assignee: InFocus CorporationInventors: Jorell A. Olson, Robin F. Hoeye, Jason G. Lewis
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Patent number: 6987104Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.Type: GrantFiled: June 14, 2002Date of Patent: January 17, 2006Assignee: Vicuron Pharmaceuticals Inc.Inventors: Jeffrey Jacobs, Rakesh K. Jain, Jason G. Lewis, Dinesh V. Patel, Zhengyu Yuan
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Patent number: 6860609Abstract: In a computing device configured to be connected to a wireless network, a method of projecting an image via a projection device over the wireless network, is provided, wherein the projection device is connected to the wireless network via an image-rendering device configured to receive data over the wireless network. The method includes detecting the image-rendering device over the wireless network, presenting a display identifying the image-rendering device to a user, receiving selection of the image-rendering device by the user and sending data representing the image from the computing device to the image-rendering device over the wireless network for projection by the projection device.Type: GrantFiled: June 2, 2003Date of Patent: March 1, 2005Assignee: InFocus CorporationInventors: Jorell A. Olson, Robin F. Hoeye, Jason G. Lewis
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Publication number: 20040230046Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.Type: ApplicationFiled: February 11, 2004Publication date: November 18, 2004Applicant: VICURON PHARMACEUTICALS INC.Inventors: Jason G. Lewis, Dinesh V. Patel, Sampath Kumar Anandan, Mikhail F. Gordeev