Abstract: Profiling and analyzing modules may be combined with hardware modules to identify a likelihood that a particular region of code in a computer program contains data that would benefit from prefetching. Those regions of code that would not benefit from prefetching may also be identified. Once a region of code has been identified, a hardware prefetcher may be selectively enabled or disable when executing code in identified code region. In some instances, once a processing device finishes executing code in the identified code region, the state of the hardware prefetcher may then be switched back to its original state. Systems, methods, and media are provided.