Patents by Inventor Jason Slingsby

Jason Slingsby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120288474
    Abstract: The present invention provides a composition comprising a modified interleukin 8 (IL-8) having increased GAG binding affinity and further inhibited or down-regulated GPCR activity compared to the respective wild type IL-8 for use in preventing or treating lung inflammation with neutrophilic infiltration, for example for the prevention or treatment of chronic obstructive pulmonary disease, cystic fibrosis, severe asthma, bronchitis, broncheolitis, acute lung injury and acute respiratory distress syndrome.
    Type: Application
    Filed: September 13, 2010
    Publication date: November 15, 2012
    Applicant: PROTAFFIN BIOTECHNOLOGIE AG
    Inventors: Andreas Kungl, Jason Slingsby, Tiziana Adage, Angelika Rek
  • Publication number: 20100298203
    Abstract: The present invention relates to novel mutants of human stromal cell-derived factor-1 which exhibit increased glycosaminoglycan (GAG) binding affinity and inhibited or down-regulated GPCR activity compared to wild type SDF-1, methods for producing these mutants and to their use for preparing medicaments for the treatment of cancer.
    Type: Application
    Filed: October 23, 2008
    Publication date: November 25, 2010
    Applicant: PROTAFFIN BIOTECHNOLOGIE AG
    Inventors: Andreas Kungl, Isa Werner, Jason Slingsby, Simi Ali, John Kirby
  • Publication number: 20030143205
    Abstract: An alpha-lentivirus vector comprising at least one alphaviral component and at least one lentiviral component, wherein the lentiviral component is capable of being packaged into a lentiviral particle after introduction of said vector into a human cell.
    Type: Application
    Filed: July 22, 2002
    Publication date: July 31, 2003
    Applicant: Oxford Biomedica (UK) Limited
    Inventors: Jason Slingsby, Kyriacos Mitrophanous, Jonathan Rohll, Alison Lawrie
  • Publication number: 20020119562
    Abstract: A method is provided for selecting an improved retroviral genome having an improved packaging efficiency which method comprises: a) introducing one or more random mutations into a retroviral genome comprising a packaging signal; b) introducing the mutagenised retroviral genome into a host cell expressing viral polypeptides required for packaging the retroviral genome; c) determining whether retroviral packaging efficiency in the cell is improved as compared with a retroviral genome comprising a non-mutated packaging signal; d) selecting a viral genome which has improved packaging efficiency.
    Type: Application
    Filed: November 15, 2001
    Publication date: August 29, 2002
    Inventors: Alan John Kingsman, Jason Slingsby, Melvyn Yap
  • Publication number: 20020102537
    Abstract: A method is provided for enhancing the production of an infectious retrovirus comprising an envelope polypeptide in a producer cell which method comprises inhibiting the expression or activity in the producer cell of an endogenous receptor which is capable of binding to the envelope polypeptide of said retroviruses.
    Type: Application
    Filed: November 15, 2001
    Publication date: August 1, 2002
    Inventors: Alan John Kingsman, Jason Slingsby, Melvyn Yap