Patents by Inventor Jason W. Brown

Jason W. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Histone deacetylase inhibitors
    Patent number: 7381825
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: June 3, 2008
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Patent number: 7375228
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: May 20, 2008
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Patent number: 7169801
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0–10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: January 30, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Publication number: 20040266769
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula
    Type: Application
    Filed: March 17, 2004
    Publication date: December 30, 2004
    Applicant: Syrrx, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Publication number: 20040254220
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula
    Type: Application
    Filed: March 17, 2004
    Publication date: December 16, 2004
    Applicant: Syrrx, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Topical antiandrogen for hair loss and other hyperandrogenic conditions
    Patent number: 6828458
    Abstract: Compound (2-hydroxy-2-methyl-N-(4-X-3-(trifluoromethyl)phenyl)-3-(2,2,2-perfluoroacylamino)propionamide) applied topically, specifically inhibits and/or eliminates cutaneous androgen receptors and thus finds cosmetic use in skin afflictions associated with excess androgens such as hair effluvium, hirsutism, acne and androgenic alopecia.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: December 7, 2004
    Assignee: Biophysica, Inc.
    Inventors: Milos Sovak, Allen L. Seligson, Brian Campion, Jason W. Brown
  • A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS
    Publication number: 20040014732
    Abstract: Compound (2-hydroxy-2-methyl-N-(4-X-3-(trifluoromethyl)phenyl)-3-(2,2,2-perfluoroacylamino)propionamide) applied topically, specifically inhibits and/or eliminates cutaneous androgen receptors and thus finds cosmetic use in skin afflictions associated with excess androgens such as hair effluvium, hirsutism, acne and androgenic alopecia.
    Type: Application
    Filed: May 25, 2000
    Publication date: January 22, 2004
    Applicant: Biophysica, Inc.
    Inventors: Milos Sovak, Allen L Seligson, Brian Campion, Jason W Brown
  • Solid phase synthesis of chemical libraries
    Publication number: 20030180804
    Abstract: The present invention provides compounds and compound libraries that are useful as protease modulators. The compounds and compound libraries are preferably made using the methods of the present invention which utilize peptide synthesis and combinatorial chemistry methods on a solid phase.
    Type: Application
    Filed: October 29, 2002
    Publication date: September 25, 2003
    Applicant: Corvas International, Inc
    Inventors: Kent E. Pryor, Ronald D. Lewis, Jason W. Brown
  • Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
    Patent number: 6472415
    Abstract: Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. The compounds bind specifically to the androgen receptor and find use in indications associated with the androgen receptor, such as cell hyperplasia dependent on androgens, hirsutism, acne and androgenetic alopecia.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: October 29, 2002
    Assignee: Biophysica, Inc.
    Inventors: Milos Sovak, Allen L. Seligson, James Gordon Douglas, III, Brian Campion, Jason W. Brown
  • Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
    Patent number: 6184249
    Abstract: Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. The compounds bind specifically to the androgen receptor and find use in the therapy of indications associated with the androgen receptor, such as, hirsutism, acne and androgenetic alopecia, and in the therapy and diagnosis of cell hyperplasia dependent on androgens.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: February 6, 2001
    Assignee: Biophysica, Inc.
    Inventors: Milos Sovak, Allen L. Seligson, James Gordon Douglass, III, Brian Campion, Jason W. Brown
  • Writing prosthesis
    Patent number: 4511272
    Abstract: A writing prosthesis includes a base adapted to be secured to the forearm of the user and includes a transparent extending portion to which a writing implement may be mounted. The base is supported for universal movement relative to a surface to be inscribed upon.
    Type: Grant
    Filed: May 16, 1983
    Date of Patent: April 16, 1985
    Assignee: Jason W. Brown
    Inventors: Jason W. Brown, Mitchell N. Ackerman