Patents by Inventor Jason Witherington

Jason Witherington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190142949
    Abstract: The present invention relates to covalent conjugates of BET inhibitors and alpha amino acid esters, processes for their preparation, compositions containing them, and to their use in the treatment of various disorders in particular inflammatory and autoimmune diseases, such as rheumatoid arthritis; and cancers.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Inventors: John Alexander BROWN, Katherine Louise Jones, Rabinder Kumar Prinjha, Jason Witherington
  • Publication number: 20180117165
    Abstract: The present invention relates to covalent conjugates of BET inhibitors and alpha amino acid esters, processes for their preparation, compositions containing them, and to their use in the treatment of various disorders in particular inflammatory and autoimmune diseases, such as rheumatoid arthritis; and cancers.
    Type: Application
    Filed: March 17, 2016
    Publication date: May 3, 2018
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: John Alexander BROWN, Katherine Louise JONES, Rabinder Kumar PRINJHA, Jason WITHERINGTON
  • Publication number: 20170145021
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: February 7, 2017
    Publication date: May 25, 2017
    Inventors: James BAILEY, Romain Luc Marie Gosmini, Olivier Mirguet, Jason Witherington
  • Patent number: 9598420
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: March 21, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: James Bailey, Romain Luc Marie Gosmini, Olivier Mirguet, Jason Witherington
  • Publication number: 20150299210
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: June 29, 2015
    Publication date: October 22, 2015
    Inventors: James BAILEY, Romain Luc Marie GOSMINI, Olivier Mirguet, Jason Witherington
  • Patent number: 9102677
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: August 11, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: James Bailey, Romain Luc Marie Gosmini, Olivier Mirguet, Jason Witherington
  • Publication number: 20120252781
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: November 3, 2010
    Publication date: October 4, 2012
    Inventors: James Bailey, Romain Luc Marie Gosmini, Olivier Mirguet, Jason Witherington
  • Patent number: 8222245
    Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: July 17, 2012
    Assignee: Glaxo Group Limited
    Inventors: Emmanuel Hubert Demont, Jag Paul Heer, John Skidmore, Ian David Wall, Jason Witherington, Thomas Daniel Heightman, David Nigel Hurst, Christopher Norbert Johnson
  • Patent number: 8207331
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: June 26, 2012
    Assignee: Glaxo Group Limited
    Inventors: Mark James Bamford, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Publication number: 20120101083
    Abstract: The present invention relates to novel compounds of formula (I) having S1P1 agonist activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Application
    Filed: June 17, 2010
    Publication date: April 26, 2012
    Applicant: GLAXO GROUP LIMITED
    Inventors: James Matthew Bailey, Rino Antonio Bit, Emmanuel Hubert Demont, Lee Andrew Harrison, Katherine Louise Jones, Christian Alan Paul Smethurst, Jason Witherington
  • Publication number: 20120101086
    Abstract: The present invention relates to novel compounds having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Application
    Filed: June 17, 2010
    Publication date: April 26, 2012
    Applicant: GLAXO GROUP LIMITED
    Inventors: James Matthew Bailey, John Alexander Brown, Emmanuel Hubert Demont, Lee Andrew Harrison, Gail Astra Lorraine Seal, Christian Alan Paul Smethurst, Jason Witherington
  • Publication number: 20100311740
    Abstract: This invention relates to newly identified imidazopyridine compounds of formula (I), to the use of such compounds in treating GERD and the like.
    Type: Application
    Filed: June 28, 2006
    Publication date: December 9, 2010
    Inventors: Mark James Bamford, Richard Leonard Elliott, Gerard Martin Paul Giblin, Antoinette Naylor, Terence Aaron Chal, Andrew Kenneth Takle, Jason Witherington
  • Publication number: 20100273771
    Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Application
    Filed: December 19, 2008
    Publication date: October 28, 2010
    Inventors: Emmanuel Hubert Demont, Jag Paul Heer, John Skidmore, Ian David Wall, Jason Witherington, Thomas Daniel Heightman, David Nigel Hurst, Christopher Norbert Johnson
  • Patent number: 7799773
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: September 21, 2010
    Assignee: Glaxo Group Limited
    Inventors: Mark James Bamford, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Publication number: 20100179168
    Abstract: The present invention therefore provides compounds of formula (I) or pharmaceutically acceptable salts thereof: (I) processes for their preparation, pharmaceutical compositions containing the same and to their use in the treatment of gastrointestinal and other disorders.
    Type: Application
    Filed: April 13, 2007
    Publication date: July 15, 2010
    Inventors: Emma Louise Blaney, David Kenneth Dean, Alessandra Gaiba, Nigel Paul King, Jason Witherington
  • Publication number: 20100145040
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: February 17, 2010
    Publication date: June 10, 2010
    Inventors: Mark James Bamford, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Patent number: 7713978
    Abstract: The present invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing the same and to their use in the treatment of gastrointestinal and other disorders.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: May 11, 2010
    Inventors: Nigel Paul King, Jason Witherington
  • Patent number: 7704994
    Abstract: The present invention relates to benzazepine derivatives of formula (I) wherein: R1 represents —C3-7 cycloalkyl optionally substituted by C1-3 alkyl; having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: April 27, 2010
    Assignee: Glaxo Group Limited
    Inventors: Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Patent number: 7696193
    Abstract: The present invention relates to benzazepine derivatives of formula (I) wherein: R1 represents —C3-7 cycloalkyl optionally substituted by C1-3 alkyl; having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: April 13, 2010
    Assignee: Glaxo Group Limited
    Inventors: Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Publication number: 20090105226
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: December 19, 2008
    Publication date: April 23, 2009
    Inventors: Mark James BAMFORD, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington