Patents by Inventor Jay A Fournier
Jay A Fournier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124490Abstract: Disclosed herein are compounds that are Hematopoietic Progenitor Kinase 1 (HPK1) inhibitors having a structure according to Formula I, and compositions containing those compounds. Methods of preparing the compounds, and methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.Type: ApplicationFiled: July 6, 2023Publication date: April 18, 2024Applicant: Arcus Biosciences, Inc.Inventors: Joshua R. Corbin, Sandeep Dhanju, Corinne Nicole Foley, Jeremy Fournier, Padmanabha V. Kattamuri, Manmohan Reddy Leleti, Pradeep Nareddy, Jay Patrick Powers, Ehesan Ul Sharif, Joice Thomas
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Patent number: 11931343Abstract: Compounds, such as compounds having Formula (I): wherein each variable is as described herein, that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.Type: GrantFiled: August 26, 2019Date of Patent: March 19, 2024Assignee: Arcus Biosciences, Inc.Inventors: Joel Beatty, Laurent Pierre Paul Debien, Samuel Lawrie Drew, Jeremy Fournier, Rebecca Louise Grange, Steven Donald Jacob, Jenna Leigh Jeffrey, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Debashis Mandal, Jay Patrick Powers, Anh Thu Tran, Rhiannon Thomas-Tran, Xuelei Yan
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Publication number: 20230345996Abstract: Electrically heated cigarettes used in an electrical smoking system include a flavoring-release additive and sorbent effective to remove one or more gas-phase constituents of mainstream tobacco smoke. The flavoring-release additive includes gamma cyclodextrin and at least one flavoring. Flavoring is released in a cigarette upon the flavoring-release additive reaching at least a minimum temperature during smoking. The flavoring-release additive can have various forms including, for example, powder and films.Type: ApplicationFiled: May 23, 2023Publication date: November 2, 2023Applicant: Philip Morris USA Inc.Inventors: Munmaya K. MISHRA, Susan E. Wrenn, Jay A. Fournier
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Patent number: 11700877Abstract: Cigarettes are provided which contain a filtering system and flavorants encapsulated with polyvinyl acetate, wherein deactivation of a sorbent by the flavorant is reduced through the encapsulation of the flavorant within the polyvinyl acetate. A preferred flavorant is menthol. The encapsulated flavorants are prepared by mixing at least one flavorant with polyvinyl acetate and a solvent, such as ethanol, and forming the encapsulated flavorants. Methods of making cigarettes and smoking the articles are also provided.Type: GrantFiled: March 6, 2020Date of Patent: July 18, 2023Assignee: Philip Morris USA Inc.Inventors: Ulrike Becker, Tony Howell, Lixin Xue, Georgios D. Karles, Jay A. Fournier
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Patent number: 11690395Abstract: Electrically heated cigarettes used in an electrical smoking system include a flavoring-release additive and sorbent effective to remove one or more gas-phase constituents of mainstream tobacco smoke. The flavoring-release additive includes gamma cyclodextrin and at least one flavoring. Flavoring is released in a cigarette upon the flavoring-release additive reaching at least a minimum temperature during smoking. The flavoring-release additive can have various forms including, for example, powder and films.Type: GrantFiled: December 23, 2019Date of Patent: July 4, 2023Assignee: Altria Client Services LLCInventors: Munmaya K. Mishra, Susan E. Wrenn, Jay A. Fournier
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Publication number: 20220132911Abstract: Delivery of additives in a smoking article is provided through thermally degradable, robust immobilized additive inserts. Additives can be immobilized in an elongated device or an insert, wherein the elongated device or the insert is sufficiently robust to allow the elongated device or the insert to be manually or machine inserted into a smoking article while maintaining the structure of the elongated device or the insert. By providing additives in the form of thermally degradable immobilized additive inserts, migration and/or loss of the additives in a smoking article prior to smoking can be reduced.Type: ApplicationFiled: January 17, 2022Publication date: May 5, 2022Applicant: Philip Morris USA Inc.Inventors: Munmaya K. MISHRA, Jay A. FOURNIER, Marc R. KRAUSS, Douglas A. FERNANDEZ, Peter J. LIPOWICZ
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Patent number: 11229233Abstract: Delivery of additives in a smoking article is provided through thermally degradable, robust immobilized additive inserts. Additives can be immobilized in an elongated device or an insert, wherein the elongated device or the insert is sufficiently robust to allow the elongated device or the insert to be manually or machine inserted into a smoking article while maintaining the structure of the elongated device or the insert. By providing additives in the form of thermally degradable immobilized additive inserts, migration and/or loss of the additives in a smoking article prior to smoking can be reduced.Type: GrantFiled: June 26, 2018Date of Patent: January 25, 2022Assignee: Philip Morris USA Inc.Inventors: Munmaya K. Mishra, Jay A. Fournier, Marc R. Krauss, Douglas A. Fernandez, Peter J. Lipowicz
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Publication number: 20200268038Abstract: Cigarettes are provided which contain a filtering system and flavorants encapsulated with polyvinyl acetate, wherein deactivation of a sorbent by the flavorant is reduced through the encapsulation of the flavorant within the polyvinyl acetate. A preferred flavorant is menthol. The encapsulated flavorants are prepared by mixing at least one flavorant with polyvinyl acetate and a solvent, such as ethanol, and forming the encapsulated flavorants. Methods of making cigarettes and smoking the articles are also provided.Type: ApplicationFiled: March 6, 2020Publication date: August 27, 2020Applicant: Philip Morris USA Inc.Inventors: Ulrike Becker, Tony Howell, Lixin Xue, Georgios D. Karles, Jay A. Fournier
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Publication number: 20200146343Abstract: Improved delivery of additive materials to cigarettes is provided through the use of one or more capsules containing additive materials, such as flavor components, in the filter section of a cigarette. The sealed capsule or capsules are subjected to an external force, such as squeezing, by a smoker prior to or during smoking of the cigarette in order to release at least a portion of the additive material from the one or more capsules and expose the additive material to mainstream smoke passing through the filter. The sealed capsules provide a barrier between the additive materials and other cigarettes components, such as sorbents or filter materials, in order to reduce additive material migration into the other cigarette components prior to desired use.Type: ApplicationFiled: January 13, 2020Publication date: May 14, 2020Applicant: Philip Morris USA Inc.Inventors: Georgios Karles, Martin Garthaffner, Richard Jupe, Diane Kellogg, Ila Skinner, Jose Nepomuceno, John Layman, Constance Morgan, Jay A. Fournier
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Publication number: 20200120971Abstract: Electrically heated cigarettes used in an electrical smoking system include a flavoring-release additive and sorbent effective to remove one or more gas-phase constituents of mainstream tobacco smoke. The flavoring-release additive includes gamma cyclodextrin and at least one flavoring. Flavoring is released in a cigarette upon the flavoring-release additive reaching at least a minimum temperature during smoking. The flavoring-release additive can have various forms including, for example, powder and films.Type: ApplicationFiled: December 23, 2019Publication date: April 23, 2020Applicant: Philip Morris USA Inc.Inventors: Munmaya K. MISHRA, Susan E. WRENN, Jay A. FOURNIER
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Patent number: 10595557Abstract: Cigarettes are provided which contain a filtering system and flavorants encapsulated with polyvinyl acetate, wherein deactivation of a sorbent by the flavorant is reduced through the encapsulation of the flavorant within the polyvinyl acetate. A preferred flavorant is menthol. The encapsulated flavorants are prepared by mixing at least one flavorant with polyvinyl acetate and a solvent, such as ethanol, and forming the encapsulated flavorants. Methods of making cigarettes and smoking the articles are also provided.Type: GrantFiled: November 11, 2016Date of Patent: March 24, 2020Assignee: Philip Morris USA Inc.Inventors: Ulrike Becker, Tony Howell, Lixin Xue, Georgios D. Karles, Jay A Fournier
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Patent number: 10568356Abstract: Improved delivery of additive materials to cigarettes is provided through the use of one or more capsules containing additive materials, such as flavor components, in the filter section of a cigarette. The sealed capsule or capsules are subjected to an external force, such as squeezing, by a smoker prior to or during smoking of the cigarette in order to release at least a portion of the additive material from the one or more capsules and expose the additive material to mainstream smoke passing through the filter. The sealed capsules provide a barrier between the additive materials and other cigarettes components, such as sorbents or filter materials, in order to reduce additive material migration into the other cigarette components prior to desired use.Type: GrantFiled: July 21, 2009Date of Patent: February 25, 2020Assignee: Philip Morris USA Inc.Inventors: Georgios Karles, Martin Garthaffner, Richard Jupe, Diane Kellogg, Ila Skinner, Jose Nepomuceno, John Layman, Constance Morgan, Jay A. Fournier
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Patent number: 10537131Abstract: Electrically heated cigarettes used in an electrical smoking system include a flavoring-release additive and sorbent effective to remove one or more gas-phase constituents of mainstream tobacco smoke. The flavoring-release additive includes gamma cyclodextrin and at least one flavoring. Flavoring is released in a cigarette upon the flavoring-release additive reaching at least a minimum temperature during smoking. The flavoring-release additive can have various forms including, for example, powder and films.Type: GrantFiled: May 1, 2017Date of Patent: January 21, 2020Assignee: Philip Morris USA Inc.Inventors: Munmaya K. Mishra, Susan E. Wrenn, Jay A Fournier
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Patent number: 10285431Abstract: Improved delivery of additives is provided through encapsulation. The encapsulated additives can be formed by encapsulating additives using co-ionic cross-linking, in-situ overcoating, and/or step-growth overcoating. By encapsulating additives, additives can be made heat and moisture stable and migration and/or loss of the additives within a cigarette, such as an activated carbon containing cigarette, can be reduced.Type: GrantFiled: December 30, 2004Date of Patent: May 14, 2019Assignee: Philip Morris USA Inc.Inventors: Munmaya K. Mishra, Jay A Fournier, Kathy E. Paine
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Patent number: 10226065Abstract: A tobacco smoking mixture and/or a cigarette wrapper with high-temperature ammonia-release agents therein are provided, wherein the high-temperature ammonia-release agents are present in an amount effective to reduce the cytotoxicity of gas phase or particulate matter formed during smoking of the cigarette. The high-temperature ammonia-release agents can be formed by heating an aqueous mixture of an iron precursor compound, an ammonia source compound and an acid.Type: GrantFiled: February 8, 2017Date of Patent: March 12, 2019Assignee: Philip Morris USA Inc.Inventors: Jay A Fournier, John B. Paine, Douglas A. Fernandez
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Patent number: 10188142Abstract: Smoking articles which involve the use of amphiphile-modified sorbents are disclosed. The amphiphile-modified sorbent has at least one amphiphilic compound bound to an inorganic molecular sieve substrate. The amphiphile-modified sorbent selectively removes certain constituents from cigarette smoke, while maintaining other constituents, such as those that contribute to flavor. Methods for making cigarette filters and smoking articles using amphiphile-modified sorbents, as well as methods for smoking a cigarette containing an amphiphile-modified sorbent, are also provided.Type: GrantFiled: December 29, 2015Date of Patent: January 29, 2019Assignee: Philip Morris USA Inc.Inventors: Jay A. Fournier, Luan Zhaohua
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Publication number: 20180295874Abstract: Delivery of additives in a smoking article is provided through thermally degradable, robust immobilized additive inserts. Additives can be immobilized in an elongated device or an insert, wherein the elongated device or the insert is sufficiently robust to allow the elongated device or the insert to be manually or machine inserted into a smoking article while maintaining the structure of the elongated device or the insert. By providing additives in the form of thermally degradable immobilized additive inserts, migration and/or loss of the additives in a smoking article prior to smoking can be reduced.Type: ApplicationFiled: June 26, 2018Publication date: October 18, 2018Applicant: Philip Morris USA Inc.Inventors: Munmaya K. Mishra, Jay A. Fournier, Marc R. Krauss, Douglas A. Fernandez, Peter J. Lipowicz
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Patent number: 10028523Abstract: Delivery of additives in a smoking article is provided through thermally degradable, robust immobilized additive inserts. Additives can be immobilized in an elongated device or an insert, wherein the elongated device or the insert is sufficiently robust to allow the elongated device or the insert to be manually or machine inserted into a smoking article while maintaining the structure of the elongated device or the insert. By providing additives in the form of thermally degradable immobilized additive inserts, migration and/or loss of the additives in a smoking article prior to smoking can be reduced.Type: GrantFiled: March 26, 2015Date of Patent: July 24, 2018Assignee: :Philip Morris USA Inc.Inventors: Munmaya K. Mishra, Jay A Fournier, Marc R. Krauss, Douglas A. Fernandez, Peter J. Lipowicz
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Publication number: 20170251714Abstract: Improved delivery of additives is provided through encapsulation. The encapsulated additives can be formed by encapsulating additives using co-ionic cross-linking, in-situ overcoating, and/or step-growth overcoating. By encapsulating additives, additives can be made heat and moisture stable and migration and/or loss of the additives within a cigarette, such as an activated carbon containing cigarette, can be reduced.Type: ApplicationFiled: May 18, 2017Publication date: September 7, 2017Applicant: PHILIP MORRIS USA INC.Inventors: Munmaya K. Mishra, Jay A Fournier, Kathy Esperdy Paine
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Publication number: 20170231266Abstract: Electrically heated cigarettes used in an electrical smoking system include a flavoring-release additive and sorbent effective to remove one or more gas-phase constituents of mainstream tobacco smoke. The flavoring-release additive includes gamma cyclodextrin and at least one flavoring. Flavoring is released in a cigarette upon the flavoring-release additive reaching at least a minimum temperature during smoking. The flavoring-release additive can have various forms including, for example, powder and films.Type: ApplicationFiled: May 1, 2017Publication date: August 17, 2017Inventors: Munmaya K. Mishra, Susan E. Wrenn, Jay A Fournier