Patents by Inventor Jay Donald Albright

Jay Donald Albright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6544984
    Abstract: Compounds having the following formula:   are useful in treating disease conditions mediated by matrix metalloproteinases and TACE, such as tumor growth, osteoarthritis, rheumatoid arthritis and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: April 8, 2003
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Efren Guillermo Delos Santos, Jeremy Ian Levin, James Ming Chen
  • Patent number: 5968937
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: October 19, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Efren Guillermo Delos Santos
  • Patent number: 5968930
    Abstract: Tricyclic diazepines of the formula: wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: October 19, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Efren Guillermo Delos Santos
  • Patent number: 5889001
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: March 30, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Patent number: 5869483
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: February 9, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Fuk-Wah Sum
  • Patent number: 5854237
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: December 29, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Patent number: 5854236
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: December 29, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Xuemei Du
  • Patent number: 5843952
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: December 1, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Fuk-Wah Sum
  • Patent number: 5843944
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: December 1, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Patent number: 5834461
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: November 10, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich
  • Patent number: 5786353
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: July 28, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Xuemei Du
  • Patent number: 5760031
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: June 2, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich
  • Patent number: 5753648
    Abstract: Tricyclic compound of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and process for preparing such compounds.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: May 19, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Aranapakam M. Venkatesan, John P. Dusza, Fuk-Wah Sum
  • Patent number: 5747487
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in viva vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: May 5, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich
  • Patent number: 5739128
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: April 14, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Xuemei Du
  • Patent number: 5736540
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: April 7, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Patent number: 5736538
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: April 7, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Xuemei Du
  • Patent number: 5733905
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: March 31, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Patent number: 5700796
    Abstract: Tricyclic compound of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and process for preparing such compounds.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: December 23, 1997
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Aranapakam M. Venkatesan, John P. Dusza, Fuk-Wah Sum
  • Patent number: 5693635
    Abstract: Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.
    Type: Grant
    Filed: June 13, 1996
    Date of Patent: December 2, 1997
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich