Patents by Inventor Jean-Francois Guichou

Jean-Francois Guichou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azaindole derivatives and their use as ERK kinase inhibitors
    Patent number: 11827637
    Abstract: The present invention concerns a compound of formula (I): or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity, in particular ERK2 activity.
    Type: Grant
    Filed: January 13, 2023
    Date of Patent: November 28, 2023
    Assignees: AGV Discovery, Institut National de la Sante et de la Recherche Medicale (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Université De Montpellier
    Inventors: Cédric Bories, Loïc Mathieu, Jean-François Guichou, Muriel Gelin, Aurélien Biechy
  • Azaindole derivatives and their use as ERK kinase inhibitors
    Patent number: 11708364
    Abstract: The present invention concerns a compound of formula (I), or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: July 25, 2023
    Assignees: AGV Discovery, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universite De Montpellier
    Inventors: Jean-François Guichou, Cédric Bories, Clément Geoffroy, Charline Duquenne, Muriel Gelin, Gilles Labesse, Yannick Bessin, Loic Mathieu
  • AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS
    Publication number: 20230227451
    Abstract: The present invention concerns a compound of formula (I): or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity, in particular ERK2 activity.
    Type: Application
    Filed: January 13, 2023
    Publication date: July 20, 2023
    Inventors: Cédric BORIES, Loïc MATHIEU, Jean-François GUICHOU, Muriel GELIN, Aurélien BIECHY
  • AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS
    Publication number: 20210221809
    Abstract: The present invention concerns a compound of formula (I), or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 22, 2021
    Applicants: AGV Discovery ENSCM, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universite De Montpellier
    Inventors: Jean-François GUICHOU, Cédric BORIES, Clément GEOFFROY, Charline DUQUENNE, Muriel GELIN, Gilles LABESSE, Yannick BESSIN, Loic MATHIEU
  • Zaindole derivatives and their use as ERK kinase inhibitors
    Patent number: 10995089
    Abstract: The present invention concerns a compound of formula (I): H or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: May 4, 2021
    Assignees: AGV DISCOVERY, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE MONTPELLIER
    Inventors: Jean-François Guichou, Cédric Bories, Clément Geoffroy, Charline Duquenne, Muriel Gelin, Gilles Labesse, Yannick Bessin, Loic Mathieu
  • ZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS
    Publication number: 20200283432
    Abstract: The present invention concerns a compound of formula (I): H or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.
    Type: Application
    Filed: November 17, 2016
    Publication date: September 10, 2020
    Applicants: AGV Discovery ENSCM, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universite de Montpellier
    Inventors: Jean-François GUICHOU, Cédric BORIES, Clément GEOFFROY, Charline DUQUENNE, Muriel GELIN, Gilles LABESSE, Yannick BESSIN, Loic MATHIEU
  • Methods and Pharmaceutical Compositions for Treatment of Gastrointestinal Stromal Tumors
    Publication number: 20150259403
    Abstract: The present invention relates to methods and compositions for the treatment of gastrointestinal stromal tumors.
    Type: Application
    Filed: October 10, 2013
    Publication date: September 17, 2015
    Inventors: Pascal De Santa Barbara, Jean-Francois Guichou
  • Inhibitors of cyclophilins and uses thereof
    Patent number: 8901295
    Abstract: The present invention relates to a compound of formula (I): wherein: n is 0, 1 or 2; A is in particular CH or N; X is in particular CO, SO2, CS, and R1 is in particular H, R2 is a group of formula NR3R4 or OR5, R3 and R4 being in particular H, and R5 an alkyl group, R6 is in particular H or an alkyl group, and R7 is in particular an aryl group, for its use in the prevention and/or the treatment of viral pathologies or infections.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: December 2, 2014
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Montpellier 1, Universite Paris-EST Creteil val de Marne, Assistance Publique-Hopitaux de Paris, Centre National de la Recherche Scientifique
    Inventors: Jean-Francois Guichou, Lionel Colliandre, Hakim Ahmed-Belkacem, Jean-Michel Pawlotsky
  • Inhibitors of cyclophilins and uses thereof
    Patent number: 8802666
    Abstract: The present invention relates to a compound of formula (I): wherein: n is 0, 1 or 2; A is in particular CH or N; X is in particular CO, SO2, CS, and R1 is in particular H, R2 is a group of formula NR3R4 or OR5, R3 and R4 being in particular H, and R5 an alkyl group, R6 is in particular H or an alkyl group, and R7 is in particular an aryl group, for its use in the prevention and/or the treatment of viral pathologies or infections.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: August 12, 2014
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Jean-Francois Guichou, Lionel Colliandre, Hakim Ahmed-Belkacem, Jean-Michel Pawlotsky
  • New Inhibitors of Cyclophilins and Uses Thereof
    Publication number: 20140179687
    Abstract: The present invention relates to a compound of formula (I): wherein: n is 0, 1 or 2; A is in particular CH or N; X is in particular CO, SO2, CS, and R1 is in particular H, R2 is a group of formula NR3R4 or OR5, R3 and R4 being in particular H, and R5 an alkyl group, R6 is in particular H or an alkyl group, and R7 is in particular an aryl group, for its use in the prevention and/or the treatment of viral pathologies or infections.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 26, 2014
    Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Jean-Francois Guichou, Lionel Colliandre, Hakim Ahmed-Belkacem, Jean-Michael Pawlotsky
  • NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF
    Publication number: 20130018044
    Abstract: The present invention relates to a compound of formula (I): wherein: n is 0, 1 or 2; A is in particular CH or N; X is in particular CO, SO2, CS, and R1 is in particular H, R2 is a group of formula NR3R4 or OR5, R3 and R4 being in particular H, and R5 an alkyl group, R6 is in particular H or an alkyl group, and R7 is in particular an aryl group, for its use in the prevention and/or the treatment of viral pathologies or infections.
    Type: Application
    Filed: December 21, 2010
    Publication date: January 17, 2013
    Inventors: Jean-Francois Guichou, Lionel Colliandre, Hakim Ahmed-Belkacem, Jean-Michel Pawlotsky
  • Cyclosporin derivatives and method for the production of said derivatives
    Patent number: 6790935
    Abstract: The invention relates to cyclosporin derivatives, whereby the peptide chain thereof comprises at least one pseudo-proline type non-natural amino acid radical. The invention also relates to a method for the production of said derivatives.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: September 14, 2004
    Assignee: Debiopharm S.A.
    Inventors: Manfred Mutter, Roland Wenger, Jean-François Guichou, Michael Keller, Thomas Ruckle, Torsten Woehr