Patents by Inventor Jean-Louis Mestas

Jean-Louis Mestas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11602327
    Abstract: Method and system for localizing a region of interest in a medium in which cavitation occurs. Method for localizing a region of interest (R) in a medium (M) in which cavitation occurs, the method comprising the steps consisting in: producing cavitation in the region of interest (R), the cavitation generating an acoustic signal, at each of at least three separate positions, detecting a cavitation signal representative of the acoustic signal of the cavitation, for at least two pairs of cavitation signals, determining a delay between the cavitation signals of each pair of cavitation signals, calculating a localization of the region of interest (R) based on the delays and the positions.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: March 14, 2023
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE LEON BERARD, UNIVERSITE CLAUDE BERNARD LYON 1, TOHOKU UNIVERSITY
    Inventors: Cyril Lafon, Jean-Louis Mestas, Maxime Lafond, Shin-Ichiro Umemura
  • Patent number: 11540806
    Abstract: This device (2) for generating ultrasonic waves in a target region of a soft solid, includes at least two ultrasound sources (32), light sources (40) distributed around a central axis (X2) of the device (2), for enlightening a zone of the soft solid via subsurface scattering, and a video camera (50), for capturing images of the zone enlightened by the lighting means. The ultrasound source (32), the light sources (40) and the video camera (50) are mounted on a body of the device (20) and oriented toward a common target zone which includes a focal point of the ultrasound sources (32). A boresight of the video camera is aligned on the central axis (X2).
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: January 3, 2023
    Assignee: Centre Léon-Bérard
    Inventors: Jean-Yves Chapelon, Jean-Louis Mestas, Cyril Lafon, Bernard Greillier, René Milleret
  • Publication number: 20190175146
    Abstract: Method and system for localizing a region of interest in a medium in which cavitation occurs. Method for localizing a region of interest (R) in a medium (M) in which cavitation occurs, the method comprising the steps consisting in: producing cavitation in the region of interest (R), the cavitation generating an acoustic signal, at each of at least three separate positions, detecting a cavitation signal representative of the acoustic signal of the cavitation, for at least two pairs of cavitation signals, determining a delay between the cavitation signals of each pair of cavitation signals, calculating a localization of the region of interest (R) based on the delays and the positions.
    Type: Application
    Filed: August 28, 2017
    Publication date: June 13, 2019
    Inventors: Cyril LAFON, Jean-Louis MESTAS, Maxime LAFOND, Shin-ichiro UMEMURA
  • Publication number: 20180317884
    Abstract: This device (2) for generating ultrasonic waves in a target region of a soft solid, includes at least two ultrasound sources (32), light sources (40) distributed around a central axis (X2) of the device (2), for enlightening a zone of the soft solid via subsurface scattering, and a video camera (50), for capturing images of the zone enlightened by the lighting means. The ultrasound source (32), the light sources (40) and the video camera (50) are mounted on a body of the device (20) and oriented toward a common target zone which includes a focal point of the ultrasound sources (32). A boresight of the video camera is aligned on the central axis (X2).
    Type: Application
    Filed: September 29, 2016
    Publication date: November 8, 2018
    Inventors: Jean-Yves CHAPELON, Jean-Louis MESTAS, Cyril LAFON, Bernard GREILLIER, René MILLERET
  • Patent number: 10004888
    Abstract: The method determines parameters to generate confocal ultrasound beams (B1,B2) inside a medium (4), and uses a device (1) comprising first and second ultrasound means (11,12) and first and second displacement members (13,14) for moving the ultrasound means (11,12). The parameters include signals s1,s2 to the ultrasound means (11,12), and the positions x1,x2 of the ultrasound means (11,12). The parameters are optimized for having a minimum amplitude a1,a2 of the signals s1,s2 and having an acoustic effect inside the medium (4).
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: June 26, 2018
    Assignees: INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), UNIVERSITE CLAUDE BERNARD, CENTRE LÉON BÉRARD
    Inventors: Jean-Yves Chapelon, Cyril Lafon, Jean-Louis Mestas
  • Publication number: 20150141734
    Abstract: The method determines parameters to generate confocal ultrasound beams (B1,B2) inside a medium (4), and uses a device (1) comprising first and second ultrasound means (11,12) and first and second displacement members (13,14) for moving the ultrasound means (11,12). The parameters include signals s1,s2 to the ultrasound means (11,12), and the positions x1,x2 of the ultrasound means (11,12). The parameters are optimized for having a minimum amplitude a1,a2 of the signals s1,s2 and having an acoustic effect inside the medium (4).
    Type: Application
    Filed: March 8, 2013
    Publication date: May 21, 2015
    Inventors: Jean-Yves Chapelon, Cyril Lafon, Jean-Louis Mestas
  • Patent number: 5293353
    Abstract: The invention relates to a method for manufacturing an acoustic sensor, and also to the sensor. The sensor comprises a piezoelectric sheet (12) mounted on a support (14) and electrically connected to electrodes (16,18) connected by electrical conductors (20,22) to a measurement device, characterized in that the assembly constituted by the sheet (12) and its support (14) is coated with a one-piece polymerizable coating layer (24) which is preferably electrically insulating, such that the portion (24a) of the coating layer (24) overlying the sheet (12) constitutes a protective layer which is rendered non-detachable or essentially non-detachable from the piezoelectric sheet (12). The method for manufacturing this sensor is extremely simple and inexpensive, and the protective layer is non-detachable.
    Type: Grant
    Filed: October 22, 1991
    Date of Patent: March 8, 1994
    Assignee: Technomed International
    Inventors: Jean-Louis Mestas, Dominique Cathignol
  • Patent number: 5251614
    Abstract: The present invention relates to a method and a device for producing an electric discharge between two electrodes. This method characterized in that the resistance to the passage of the electric arc, at least between the electrodes, is considerably reduced so as to bring it to a resistance value near to or slightly higher than the critical resistance, by interposing at least between the electrodes, an electrically conductive electrolyte contained in an essentially closed reservoir surrounding the electrodes. The invention makes it possible to improve the rate of discharge of an electric current produced between the electrodes, by eliminating substantially completely the latency time.
    Type: Grant
    Filed: December 18, 1991
    Date of Patent: October 12, 1993
    Assignees: Technomed International, ISERM
    Inventors: Dominique Cathignol, Jean-Louis Mestas, Paul Dancer, Maurice Bourlion
  • Patent number: 5233980
    Abstract: The invention relates to a process for manufacturing a device generating shockwaves which are only slightly, if at all, felt be the patients.This shockwave generating device comprises a truncated ellipsoidal reflector (12) which has a ratio (b)/(a) greater than 0.69, and preferably between 0.60 and 0.85 and a connection (14) supplying electric current to the electrodes (6, 8), which connection comprises a capacitor (18) having a capacitance less than or equal to 500 nanofarads.The result is a reduction of the energy density at skin level of the emitted shockwaves which are only slightly, if at all, felt by the patients, thus permitting a treatment without anaesthesia.
    Type: Grant
    Filed: May 15, 1990
    Date of Patent: August 10, 1993
    Assignees: Technomed International Societe Anonyme, INSERM
    Inventors: Jean-Louis Mestas, Dominique Cathignol, Bernard Lacruche
  • Patent number: 5105801
    Abstract: The present invention relates to a method and device for discharging an electric current between two electrodes, comprising considerably reducing the resistance to the passage of electric current at least between the electrodes so as to bring it to a resistance value near to or slightly higher than the critical resistance by interposing a conductive electrolyte between electrodes. This improves the rate of discharge of an electric current produced between the electrodes, by eliminating substantially completely the latency time.
    Type: Grant
    Filed: August 2, 1991
    Date of Patent: April 21, 1992
    Assignees: Technomed International, INSERM
    Inventors: Dominique Cathignol, Jean-Louis Mestas, Paul Dancer, Maurice Bourlion
  • Patent number: 5085206
    Abstract: A method and apparatus for coordinating the initial positions in three dimensions of a device (10) for triggering and focusing shots and a locating arm (14). The apparatus includes structure (20) for calibrating the distance (D) between the free end (14a) of the locating arm (14) and the device (10) for triggering and focusing shots, the calibration structure (20) preferably comprising a link member (22). The invention improves the accuracy with which a target is located and, therefore, the effectiveness with which it is destroyed.
    Type: Grant
    Filed: October 9, 1990
    Date of Patent: February 4, 1992
    Assignees: Technomed International, INSERM
    Inventors: Jean-Louis Mestas, Bernard Lacruche, Dominique Cathignol
  • Patent number: 5015929
    Abstract: The invention relates to a device generating ultrasonic waves focused in a ocal point. Said generator device comprises a plurality of transducer elements arranged externally on a support means for focusing into a focal point, such as a circular dome, and is characterized in that the transducer elements are divided into at least two groups of transducer elements, of which the resonance frequency differs in such a way that the principal positive ultrasonic waves produced by each group add up together and the positive and negative secondary ultrasonic waves are at least partly cancelled, thus reducing significantly the negative waves. This device can be advantageously used for extracorporeal lithotripsy.
    Type: Grant
    Filed: December 1, 1989
    Date of Patent: May 14, 1991
    Assignees: Technomed International, S.A., Institut National de la Sante et de la Recherche Medical (INSERM)
    Inventors: Dominique Cathignol, Bernard Lacruche, Jean-Louis Mestas
  • Patent number: 4962753
    Abstract: The invention relates to a method and to a device for improving the dische regime of an electric arc produced between two electrodes. The device is characterized in that it includes means an insulating element (32), preferably spherical in shape, for increasing the resistance to the passage of the electric arc (A) between ends of the electrodes (12, 14). By using the invention it is possible to obtain an arc discharge of the critically damped type. The method and the device are preferably used in shock wave generator apparatus for hydraulic lithotripsy.
    Type: Grant
    Filed: June 15, 1988
    Date of Patent: October 16, 1990
    Assignees: Technomed International, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Dominique Cathignol, Bernard Lacruche, Jean-Louis Mestas
  • Patent number: 4915094
    Abstract: This invention relates to an apparatus for generating high frequency shock waves, which comprises a generator of shock waves by electric discharge between at least two electrodes disposed at least in part in a chamber filled with liquid, and advantageously supplied intermittently with electric current from a source of electric current via a supply connection, the generator device allowing the focusing of the shock waves on a target, and is characterized in that the supply connection for supplying electric current to the electrodes is disposed inside a substantially closed tubular element in order to limit or prevent electro-magnetic leakages. This tubular element is preferably mounted to move in any point in space relatively to the frame and supports the shock wave generating device. Thanks to this apparatus, electro-magnetic leakages are limited or prevented and patients' safety is therefore improved.
    Type: Grant
    Filed: November 17, 1988
    Date of Patent: April 10, 1990
    Assignees: Technomed International, Inserm
    Inventors: Bernard Lacruche, Gerard Hascoet, Dominique Cathignol, Jean-Louis Mestas
  • Patent number: 4866330
    Abstract: This invention relates to a device for advancing an electrode-holder elem in particular mounted on a pulse generating apparatus of the type described in U.S. Pat. No. 2,559,227 to Rieber. This advance device comprises a radially projecting element fast with the rear part of the electrode-holder element and member for controlling same, the radially projecting element being formed by a toothed wheel of fixed axial position with respect to the insulating support and controlled in rotation by two pistons mounted symmetrically on either side of the wheel to control a rotation in both directions. This device allows a greater precision of the advance of the electrodes and an increase in the efficiency of destruction of the targets.
    Type: Grant
    Filed: December 9, 1987
    Date of Patent: September 12, 1989
    Assignees: Technomed International, S.A., Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Bernard Lacruche, Jean-Louis Mestas, Dominique Cathignol
  • Patent number: 4730614
    Abstract: This invention relates to a device for advancing an electrode-holder elem in particular mounted on a pulse generating apparatus of the type described in U.S. Pat. No. 2,559,227 to Rieber. This advance device comprises a radially projecting element fast with the rear part of the electrode-holder element and a member for controlling same, the radially projecting element being formed by a toothed wheel of fixed axial position with respect to the insulating support and controlled in rotation by two pistons mounted symmetrically on either side of the wheel to control a rotation in both directions. This device allows a greater precision of the advance of the electrode and an increase in the efficiency of destruction of the targets.
    Type: Grant
    Filed: June 11, 1986
    Date of Patent: March 15, 1988
    Assignees: Technomed International, Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Bernard Lacruche, Jean-Louis Mestas, Dominique Cathignol
  • Patent number: 4702248
    Abstract: An apparatus for generating high frequency shock waves having a truncated ellipsoidal reflector is provided. The apparatus has a cavity which constitutes a chamber for reflecting shock waves, the chamber being filled with a dielectric liquid such as water or oil. The apparatus also has a shock wave generator device which generally has two electrodes and a source for selectively and substantially instantaneously providing an electric voltage to the electrodes. The equipotential screen is fast with the ellipsoidal reflector and is grounded by the support formed by the ellipsoidal reflector. This equipotential screen limits electric leakage and thus renders the apparatus safer in operation for destroying targets such as tissues, biliary concretions, kidney stones, etc.
    Type: Grant
    Filed: October 27, 1987
    Date of Patent: October 27, 1987
    Assignees: Technomed International, Institut National de la Sante et de la Recherche Medicale
    Inventors: Jean-Louis Mestas, Dominique Cathignol