Patents by Inventor Jean-Louis Tayot

Jean-Louis Tayot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10456500
    Abstract: A new preparation for regenerating tissues or healing wounds, which can be administered to a patient, which comprises serum and globin being insoluble at physiological pH, said preparation being obtained by adding said serum to said globin being insoluble at physiological pH.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: October 29, 2019
    Assignee: KHORIONYX
    Inventors: Jean-Louis Tayot, Jean Bernasconi
  • Publication number: 20160279293
    Abstract: A new preparation for regenerating tissues or healing wounds, which can be administered to a patient, which comprises serum and globin being insoluble at physiological pH, said preparation being obtained by adding said serum to said globin being insoluble at physiological pH.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 29, 2016
    Inventors: Jean-Louis TAYOT, Jean BERNASCONI
  • Patent number: 8853361
    Abstract: The invention relates to a sterile preparation which can be implanted on or in organic tissues, comprising: a natural or modified globin material which is insoluble at physiological pH and/or a material obtainable from globin which has been modified to be soluble at physiological pH, the said materials being biocompatible and biodegradable in the organism; an agent selected from natural or synthetic polymeric adhesive agents, polymeric tissue enhancement or filling agents, more particularly an agent based on crosslinked hyaluronic acid or on polylactic acid, and a polymeric wound cicatrization agent, specifically oxidized cellulose; with the provisos that, if the preparation comprises the said material obtainable from globin modified so as to be at least partly soluble, the said polymeric adhesive agent, if present, is not hyaluronic acid or carboxymethylcellulose and the said polymeric enhancement or filling agent, if present, is an agent based on crosslinked hyaluronic acid, and that, if the preparation com
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: October 7, 2014
    Assignee: Khorionyx
    Inventor: Jean-Louis Tayot
  • Publication number: 20120183501
    Abstract: Method for treatment of skin wounds, in a patient needing it, in which an effective amount of an insoluble globin preparation is placed in direct contact with the skin wound, the preparation is kept in place for at least one week, without having to change or wash the wound during said time and without a local infection, which would be detrimental to the patient.
    Type: Application
    Filed: November 10, 2011
    Publication date: July 19, 2012
    Inventor: Jean-Louis Tayot
  • Patent number: 7709017
    Abstract: An implantable preparation comprises a material which can be obtained from globin that has been modified, especially chemically, to be, at least partially, soluble at physiological pH. The material is biocompatible, and biodegradable in the organism. The material may be soluble at physiological pH, or insoluble at that pH. The preparation may be in the form of a solution, suspension, paste, gel, film, sponge, powder or granules, or a solid implant. The preparation can be used for the healing, protection or filling of external skin wounds, the filling of wrinkles and skin flaws, the filling of tissue, as a device for fixing prostheses or biomaterials, or as a device for preventing adhesion.
    Type: Grant
    Filed: August 7, 2006
    Date of Patent: May 4, 2010
    Assignee: Khorionyx
    Inventor: Jean Louis Tayot
  • Publication number: 20090312239
    Abstract: The invention relates to a sterile preparation which can be implanted on or in organic tissues, comprising: a natural or modified globin material which is insoluble at physiological pH and/or a material obtainable from globin which has been modified to be soluble at physiological pH, the said materials being biocompatible and biodegradable in the organism; an agent selected from natural or synthetic polymeric adhesive agents, polymeric tissue enhancement or filling agents, more particularly an agent based on crosslinked hyaluronic acid or on polylactic acid, and a polymeric wound cicatrisation agent, specifically oxidized cellulose; with the provisos that, if the preparation comprises the said material obtainable from globin modified so as to be at least partly soluble, the said polymeric adhesive agent, if present, is not hyaluronic acid or carboxymethylcellulose and the said polymeric enhancement or filling agent, if present, is an agent based on crosslinked hyaluronic acid, and that, if the preparation com
    Type: Application
    Filed: January 24, 2007
    Publication date: December 17, 2009
    Inventor: Jean-Louis Tayot
  • Publication number: 20090074736
    Abstract: Preparations comprising, especially, globin that is insoluble at neutral pH, and therefore at physiological pH, in which the globin has been obtained from whole blood by depigmentation in a medium that extracts or dissolves the haem but leaves the globin and the other constituents of proteinic nature in a substantially undissolved state, a process for the production of those preparations, and uses, especially for the filling, healing or regeneration of tissues, especially for chronic wounds and osseous healing or regeneration.
    Type: Application
    Filed: September 10, 2008
    Publication date: March 19, 2009
    Inventors: Jean-Louis Tayot, Florent Sapin, Jean Bernasconi
  • Publication number: 20090054350
    Abstract: The invention relates to a process for the preparation of sterile collagen, especially injectable collagen, comprising the steps of preparing a purified acidic collagen solution, filtering that solution through a filter or a sterile membrane, precipitating the filtered solution in the form of a suspension, and concentrating the collagen suspension, in which process the suspension is placed in an elongate supple tubular filter constituting a porous filtering wall, permeable to the liquid but not permeable to the collagen fibres, and is concentrated by the slow passage of the liquid through the wall, without any pressure other than gravity, in order to prevent the filtering wall from becoming clogged by the collagen fibres, optionally with absorption of the liquid by an absorbent layer covering the wall or forming part of that wall, and the subsequent flowing-away and/or evaporation of the liquid via the face of the layer remote from the wall, and collagen preparations obtained.
    Type: Application
    Filed: August 19, 2008
    Publication date: February 26, 2009
    Inventors: Jean-Louis Tayot, Florent Sapin
  • Publication number: 20070032805
    Abstract: The present invention relates to a three-dimensional prosthetic fabric comprising a first face and a second face, the said first face and the said second face being opposite each other and separated by the thickness of the said fabric, the said first face being porous, characterized in that the said second face is dense and made of at least one first resorbable yarn. The invention also relates to a process for preparing such a fabric and to a prosthesis obtained using such a fabric.
    Type: Application
    Filed: July 28, 2006
    Publication date: February 8, 2007
    Applicant: SOFRADIM PRODUCTION
    Inventors: Michel Therin, Alfred Meneghin, Jean-Louis Tayot, Suzelei Montanari
  • Patent number: 6949625
    Abstract: A preparation is provided which can be injected or implanted into the human or animal body, and which comprises, as main component, globin that is insoluble at physiological pH, biocompatible and sterile.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: September 27, 2005
    Assignee: Khorionyx
    Inventor: Jean-Louis Tayot
  • Publication number: 20040248774
    Abstract: The invention relates to a preparation that can be injected or implanted into the human or animal body, which comprises, as main component, globin that is insoluble at physiological pH, biocompatible and sterile.
    Type: Application
    Filed: May 11, 2004
    Publication date: December 9, 2004
    Inventor: Jean-Louis Tayot
  • Patent number: 6730299
    Abstract: A biocompatible fluid adhesive protein foam, which is bioresorbable and nontoxic, for surgical and/or therapeutic use, in particular for protecting/cicatrizing tissue wounds and for attaching biological tissues to each other or to an implanted biomaterial. The biocompatible fluid adhesive protein foam includes a biocompatible fluid adhesive protein matrix, which is bioresorbable and nontoxic, containing a biocompatible and nontoxic gas or mixture of gases. Further, a process and a kit for preparing such a foam are provided.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: May 4, 2004
    Assignee: Imedex Biomateriaux
    Inventors: Jean-Louis Tayot, Yves Bayon, Philippe Gravagna, Michel Marie Dubois
  • Patent number: 6706684
    Abstract: The invention concerns a method for preparing a non-toxic, sterile, biocompatible, crosslinked collagen material with controlled in vivo biodegradation speed. It consists in subjecting a collagen constituent, either to beta radiation, or to gamma radiation. The collagen material obtained is biodegradable in a few days depending on the type of irradiation used.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: March 16, 2004
    Assignee: Imedex Biomateriaux
    Inventors: Yves Bayon, Philippe Gravagna, Jean-Louis Tayot
  • Patent number: 6605066
    Abstract: A device for the formation and delivery of a mixture, notably a surgical adhesive, consisting of a receptacle adapted for easy handling by the surgeon, and including the means of receiving two syringe barrels containing the constituents of the mixture, the means of simultaneously expelling the contents, the means of maintaining the contents of syringe containing the first constituent, at a predetermined temperature setting which is higher than body temperature, and a mixer simultaneously receiving the contents of the two syringes, and the mixer also being used for cooling.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: August 12, 2003
    Assignee: Imedex Biomateriaux
    Inventors: Philippe Gravagna, Jean-Louis Tayot
  • Patent number: 6451032
    Abstract: The composite prosthesis comprises a prosthetic fabric having a three-dimensional structure separating two surfaces, one of which is open to post-surgical cell colonization. The composite prosthesis further comprises at least one film of a collagenous material linked to the other surface of the prosthetic fabric. The composite prosthesis may be used to prevent post-surgical adhesion.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: September 17, 2002
    Assignees: Sofradim Production, Imedex Biomateriaux
    Inventors: François Régis Ory, Michel Therin, Philippe Gravagna, Jean-Louis Tayot
  • Patent number: 6391939
    Abstract: The present invention relates to a biocompatible collagenous material which is non-toxic and biodegradable in less than one month, preferably in less than one week. This material comprises collagen and at least one hydrophilic macromolecular additive which is chemically non-reactive towards the collagen, with the collagen having at least partially lost its helical structure and being crosslinked. The invention also relates to a process for obtaining such a material. The collagenous material according to the invention is used, in particular, for preventing post-operative adhesions.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: May 21, 2002
    Assignee: Imedex Biomateriaux
    Inventors: Jean-Louis Tayot, Michel Tardy, Philippe Gravagna
  • Patent number: 6372510
    Abstract: The present invention is drawn to method for removing unconventional transmissible agents (UCTA) from aqueous protein solution. This method involves treating the aqueous protein solution with simultaneous electrostatic adsorption and hydrophobic chromatography. The method of the present invention is particularly suitable for treating calf serum or an albumin solution.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: April 16, 2002
    Assignee: Pasteur Merieux Serum et Vaccins
    Inventors: Michel Grandgeorge, René Labatut, Jean-Marc Rouzioux, Jean-Louis Tayot, Jean-Luc Veron
  • Publication number: 20010008930
    Abstract: The present invention relates to a biocompatible collagenous material which is non-toxic and biodegradable in less than one month, preferably in less than one week. This material comprises collagen and at least one hydrophilic macromolecular additive which is chemically non-reactive towards the collagen, with the collagen having at least partially lost its helical structure and being crosslinked.
    Type: Application
    Filed: August 5, 1999
    Publication date: July 19, 2001
    Inventors: JEAN-LOUIS TAYOT, MICHEL TARDY, PHILIPPE GRAVAGNA
  • Patent number: 6165488
    Abstract: A biocompatible, bioresorbable and nontoxic adhesive composition for surgical and/or therapeutic use, especially for the bonding of biological tissues to one another or to an implanted biomaterial, is provided which comprises at least one biodegradable macromolecular polyaldehyde of natural origin in aqueous solution and a collagen-based component dissolved in aqueous medium. A process for preparing this composition is also provided wherein these aqueous components are mixed together (e.g., at neutral, physiological pH) to give a gel which is rapidly applied to tissues and/or biomaterial to achieve binding. The present invention is advantageous in that it provides biodegradable macromolecular polyaldehydes with adhesive properties and the ability to be extremely well tolerated by the recipient while retaining their adhesive properties during their retention in the body.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: December 26, 2000
    Assignee: Societe Anonyme de Developpement des Utilisations du Collagene S.A.D.U.C.
    Inventors: Michel Tardy, Herve Volckmann, Jerome Tiollier, Philippe Gravagna, Jean-Louis Tayot
  • Patent number: RE39172
    Abstract: A bicomposite material based on collagen is prepared which has two closely bound layers and is biocompatible, non-toxic, hemostatic and biodegradable in less than a month, and can be used in surgery to achieve hemostasis and prevent post-surgical adhesion. To prepare the material, a solution of collagen or gelatin, which may contain glycerine and a hydrophilic additive such as polyethylene glycol or a polysaccharide, is poured onto an inert support to form a layer 30 ?m to less than 100 ?m thick. Then a polymeric porous fibrous layer is applied during gelling of the collagen or gelatin, and the resultant material is dried. The polymeric porous fibrous layer may be made of collagen or a polysaccharide, and have a density of not more than 75 mg/cm2, a pore size from 30 ?m to 300 ?m and a thickness of 0.2 cm to 1.5 cm.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: July 11, 2006
    Assignee: Imedex Biomateriaux
    Inventors: Yves Bayon, Philippe Gravagna, Jean-Louis Tayot