Patents by Inventor Jean-Marie Autin

Jean-Marie Autin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060135785
    Abstract: The present invention relates to novel analide derivatives of formula I, enantiomers and stereoisomers thereof, and their pharmaceutically acceptable salts. The invention also relates to pharmaceutical compositions containing the compounds and methods of treating hypercholesterolemia and atherosclerosis therewith.
    Type: Application
    Filed: October 15, 2003
    Publication date: June 22, 2006
    Applicant: Pierre Fabre Medicament
    Inventors: Jean-Francois Patoiseau, Jean-Marie Autin, Andre Delhon, Didier Junquero
  • Patent number: 5990173
    Abstract: Novel 2,3,5-trimethyl-4-hydroxyanilide derivatives of general formula I, wherein, e.g., R.sub.1 is phenyl, R.sub.2 is H, R.sub.3 is C.sub.12 H.sub.25, and A is a sulphur atom, are disclosed. A method for preparing said derivatives, pharmaceutical compositions containing at least one of said compounds as active principle, and the use of such derivatives for treating hypercholesterolemia or atherosclerosis.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: November 23, 1999
    Assignee: Pierre Fabre Medicament
    Inventors: Jean-Fran.cedilla.ois Patoiseau, Jean-Marie Autin, Andre Delhon, Philippe Oms, Didier Junquero
  • Patent number: 5760087
    Abstract: The invention relates to new derivatives of glycylanilides having general formula (I), wherein, particularly, R.sub.1, R.sub.3, R.sub.4, R.sub.8, R.sub.9 represent CH.sub.3 ; R.sub.2, R.sub.5, R.sub.6, R.sub.7 represent H; R.sub.10 represents C.sub.12 H.sub.25 and A is a sulfur atom. It also relates to the preparation process and the pharmaceutical compositions comprising as active principle at least one of said compounds, as well as the utilization of said derivatives for the fabrication of drugs intended to the treatment of hypercholesterolemy or atherosclerosis.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: June 2, 1998
    Assignee: Pierre Fabre Medicament
    Inventors: Jean-Francois Patoiseau, Jean-Marie Autin, Andre Delhon, Philippe Oms
  • Patent number: 5633255
    Abstract: 1,2-dihydro-2-oxo-3-amino-quinoxaline derivatives of general formula (I) in which R.sub.1 and R.sub.2 are independently hydrogen or a straight or branched C.sub.1 -C.sub.4 alkyl radical, R.sub.3 is a straight or branched C.sub.3 -C.sub.6 alkyl, alkenyl or hydroxy-alkyl grouping, their salts with pharmaceutically-acceptable acids, and a method for preparing them and their use in therapy are disclosed.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: May 27, 1997
    Assignee: Pierre Fabre Medicament
    Inventors: Dennis Bigg, Jean-Francois Patoiseau, Jean-Marie Autin, Jean-Pierre Tarayre
  • Patent number: 5254554
    Abstract: The application discloses pharmacologically-active 3-hydroxy-1-phenyl-1,4-dihydro-4-oxopyridazine compounds, derivatives thereof, a method for the preparation thereof, pharmaceutical compositions thereof, and a method of treating anxiety and other physiological abnormalities therewith.
    Type: Grant
    Filed: May 20, 1992
    Date of Patent: October 19, 1993
    Assignee: Pierre Fabre Medicament
    Inventors: Jean-Marie Autin, Dennis Bigg, Jean-Francois Patoiseau
  • Patent number: 5091415
    Abstract: Formamidine compounds of general formula I ##STR1## in which: R.sub.1 represents H or C.sub.1-4 alkyl,R.sub.2 represents benzoyl, benzyl, or alpha-hydroxybenzyl, the aromatic ring being optionally substituted by a halogen atom,R.sub.3 and R.sub.4, which are identical or different, represent hydrogen, lower-alkyl, or lower-alkenyl, or form between them with the formamidine function a heterocycle,R.sub.5 represents hydrogen or C.sub.1-4 lower-alkyl or forms with R.sub.4 a double bond (--N.dbd.R.sub.4) in the case of pseudoaromatic heterocycles,n equals 0 or 1,A represents a linear or branched C.sub.1-4 alkylene chain,X represents hydrogen, halogen, C.sub.1-4 lower-alkyl, C.sub.1-4 lower-alkoxy, or nitro, and pharmaceutically-acceptable salts thereof, are disclosed.The compounds and pharmaceutical compositions thereof are used, optionally in combination with other active principles, as drugs for the treatment of gastrointestinal ailments, especially as gastric antisecretory and antiulcer agents.
    Type: Grant
    Filed: October 15, 1990
    Date of Patent: February 25, 1992
    Assignee: Pierre Fabre Medicament
    Inventors: Jean F. Patoiseau, Jean-Marie Autin, Henri Cousse, Veronique Sales, Jacky Tisne-Versailles, Jean-Pierre Bali
  • Patent number: 5059599
    Abstract: The present invention relates to derivatives of 1-phenyl 1,4-dihydro 3-amino 4-oxo pyridazines of the general formula I: ##STR1## and the production thereof. It also concerns pharmaceutical compositions comprising as active principle a compound of general formula I and use thereof for treatment of central nervous system disturbances, especially as an anxiolytic.
    Type: Grant
    Filed: June 6, 1990
    Date of Patent: October 22, 1991
    Assignee: Pierre Fabre Medicament
    Inventors: Gilbert Mouzin, Henri Cousse, Jean-Francois Patoiseau, Jean-Marie Autin, Dennis Bigg
  • Patent number: 5025015
    Abstract: Formamidine compounds of general formula I ##STR1## in which: R.sub.1 represents H or C.sub.1-4 alkyl,R.sub.2 represents benzoyl, benzyl, or alphahydroxybenzyl, the aromatic ring being optionally substituted by a halogen atom,R.sub.3 and R.sub.4, which are identical or different, represent hydrogen, lower-alkyl, or lower-alkenyl, or form between them with the formamidine function a heterocycle,R.sub.5 represents hydrogen or C.sub.1-4 lower-alkyl or forms with R.sub.4 a double bond (--N.dbd.R.sub.4) in the case of pseudoaromatic heterocycles,n equals 0 or 1,A represents a linear or branched C.sub.1-4 alkylene chain,X represents hydrogen, halogen, C.sub.1-4 lower-alkyl, C.sub.1-4 lower-alkoxy, or nitro, and pharmaceutically-acceptable salts thereof, are disclosed.The compounds and pharmaceutical compositions thereof are used, optionally in combination with other active principles, as drugs for the treatment of gastrointestinal ailments, especially as gastric antisecretory and antiulcer agents.
    Type: Grant
    Filed: September 7, 1989
    Date of Patent: June 18, 1991
    Assignee: Pierre Fabre Medicament
    Inventors: Jean F. Patoiseau, Jean-Marie Autin, Henri Cousse, Veronique Sales, Jacky Tisne-Versailles, Jean-Pierre Bali