Abstract: The present invention provides anti-9,10-dihydro-4-(1-methyl-4-piperidylidene)-4H-benzo[4,5]-cyclohepta[1 ,2-b]thiophen-10(9H)-one oxime of formula ##STR1## useful for the treatment of allergic conditions.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, chlorine or lower alkyl,R.sub.2 is lower alkyl,R.sub.3 is lower alkyl, each ofA and B is hydrogen, orA and B together form a bond,useful as luteinizing hormone secretion inhibitors, e.g. for the treatment of prostate hypertorphy.

Abstract: The present invention provides compounds of formula, ##STR1## wherein n is from 0 to 4, m is from 0 to 4, whereby n+m is at least 1 and not more than 4, each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 may independently be, for example, hydrogen, alkyl or alkoxy, R.sub.5 may, for example, be nitrile or carbamoyl and R.sub.6 is hydrogen and, when n is 2 and m is 0, one of R.sub.6 can be alkyl of 1 to 4 carbon atoms, which compounds possess pharmaceutical, for example antiallergic, activity.

Abstract: The present invention provides novel compounds of the formula, ##STR1## wherein R.sub.1 is hydrogen, halogen, alkyl or alkoxy; R.sub.2 may, for example, be hydrogen, alkyl, alkenyl, alkinyl or phenylalkyl, the phenyl ring of which may be mono-substituted with halogen, alkyl or alkoxy; and R.sub.3 is hydrogen, alkyl, thienyl, phenyl or phenyl which may be mono- or di-substituted with halogen, alkyl, alkoxy or alkylthio, useful, for example, as anti-depressants and analgesics.

Abstract: The invention provides compounds of formula I, ##STR1## wherein each of R.sub.1 and R.sub.4, which may be the same or different, is hydrogen, halogen, alkyl or alkoxy; each of R.sub.2 and R.sub.3 is hydrogen, or together, oxygen; B and D together with the carbon atoms to which they are bound may be a benzene ring or a substituted or unsubstituted thiophene ring and A may, for example, be oxygen, sulpur, --CH.sub.2 --O--, --CH.sub.2 --S, ethylene or vinylene, useful as psychostimulants and vigilance-increasing agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of atomic number from 9 to 35 or lower alkyl,R.sub.2 is hydrogen or lower alkyl, each ofR.sub.3 and R.sub.4 is hydrogen, orR.sub.3 and R.sub.4 together are oxygen,N is 2, 3 or 4, andA is ethylene or vinylene,Useful as antiphlogistics and anti-arthritics.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of an atomic number from 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms,R.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl or alkynyl of 3 to 6 carbon atoms, in which the multiple bond is located in a position other than the .alpha.,.beta. position, hydroxyalkyl of 2 to 5 carbon atoms in which the hydroxy group is separated from the nitrogen atom of the tricyclic ring system by at least 2 carbon atoms, alkanoylalkyl of 3 to 5 carbon atoms, or phenylalkyl of 7 to 10 carbon atoms in which the phenyl ring is unsubstituted or mono-substituted by halogen of atomic number 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms, andEitherR.sub.3 is hydrogen, alkyl of 1 to 4 carbon atoms, or phenylalkyl of 7 to 10 carbon atoms in which the phenyl ring is unsubstituted or mono-substituted by halogen of atomic number from 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms, andR.sub.4 is hydrogen,OrR.sub.3 and R.sub.

Abstract: The invention concerns novel compounds of the formula: ##STR1## wherein n is 1, 2 or 3 R.sub.1 is lower alkylR.sub.2 is hydrogen or lower alkyl andA is a tricyclic moiety,Useful as sedative-neuroleptic, muscle-relaxant and sleep-promoting agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of atomic number from 9 to 35 or lower alkyl,R.sub.2 is hydrogen or lower alkyl, each ofR.sub.3 and R.sub.4 is hydrogen, orR.sub.3 and R.sub.4 together are oxygen,n is 2, 3 or 4, andA is ethylene or vinylene,Useful as antiphlogistics and anti-arthritics.

Abstract: Novel benzo[5,6]cyclohepta[1,2-c]pyridines useful as anti-depressant and anti-cholinergic agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of atomic number from 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms,R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms,R.sub.3 is hydrogen, chlorine, or alkyl of 1 to 4 carbon atoms,Either A and B are each hydrogen or together a single bond, andn is a whole number from 3 to 7, useful as salidiuretics.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein N IS A WHOLE NUMBER FROM 1 TO 3,R.sub.1 is hydrogen, or halogen of atomic number from 9 to 35,Each of the two radicals R.sub.2 are the same, and each is hydrogen or alkyl of 1 to 4 carbon atoms,Each of the two radicals R.sub.3 are the same, and each is hydrogen or alkyl of 1 to 4 carbon atoms, andX is carbonyl or methylene,Useful as anti-arrhythmics.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, alkyl or 1 to 4 carbon atoms, fluorine, chlorine or bromine,R.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms, cycloalkylalkyl of 4 to 10 carbon atoms, alkenyl or alkinyl of 3 to 6 carbon atoms, the multiple bond thereof being other than adjacent to the nitrogen atom of the tricyclic ring system, oxoalkyl of 2 to 5 carbon atoms, the oxygen atom thereof being separated by at least two carbon atoms from the nitrogen atom of the tricyclic ring system, or phenylalkyl of 7 to 10 carbon atoms,R.sub.3 is hydrogen or alkyl of 1 to 4 carbon atoms,And R.sub.4 is hydrogen or alkyl of 1 to 4 carbon atoms,Useful as antidepressants.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of an atomic number of from 9 to 35, or alkyl of 1 to 4 carbon atoms,R.sub.2 is alkyl of 1 to 4 carbon atoms,R.sub.4 is alkyl of 1 to 4 carbon atoms, and eitherI.R.sub.3 is hydrogen or alkyl of 1 to 4 carbon atoms, andA and B together form a bond, orIi.R.sub.3 is hydrogen, andA and B are both hydrogen,Useful as LH inhibitors and antidepressants.

Abstract: The invention concerns novel indenopyridine derivatives of the formula: ##SPC1##Wherein m is 1, 2, 3 or 4, andR.sub.3 is an --O--R.sub.4 group,Wherein R.sub.4 is alkyl of 1 to 5 carbon atoms, phenyl or phenylalkyl, wherein the alkyl radical is of 1 to 4 carbon atoms, or an ##EQU1## group, WHEREIN EACH OFR.sub.5 and R.sub.6 is, independently, hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or phenyl-alkyl, wherein the alkyl radical is of 1 to 4 carbon atoms, orR.sub.5 and R.sub.6 together with the nitrogen atom form a saturated 5- or 6-membered heterocyclic ring, the heterocycle being selected from heterocycles containing 1 nitrogen atom, 1 nitrogen atom and 1 oxygen atom, and 1 nitrogen atom and a further nitrogen atom substituted by an alkyl radical of 1 to 4 carbon atoms,Useful as anti-aggressives and in the treatment of excitation conditions.

Abstract: The present invention concerns new heterocyclic compounds of the formula: ##SPC1##WhereinR.sub.1 and R.sub.2 are inter alia alkyl, chlorine or methoxy,R.sub.3 is hydroxy, alkylcarboxy or monoalkylcarbamoyloxy, andA is protected or unprotected carbonyl.The compounds possess analgesic and central nervous system depressant properties.