Patents by Inventor Jean Qiu

Jean Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911764
    Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: February 27, 2024
    Assignee: Nexcelom Bioscience LLC
    Inventors: Peter Y. Li, Jean Qiu, Leo L. Chan, Justin R. Hascup, Timothy F. Smith, Todd R. Sobolewski, Nicholas N. Shaw
  • Publication number: 20220307966
    Abstract: The invention provides novel sample chambers, units and multi-well plates, and systems and methods thereof, for built-in measurement assurance of cell counting methods and calibrated and/or quality-assured measurement and analysis of diverse types of biological cells, e.g., cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
    Type: Application
    Filed: September 2, 2020
    Publication date: September 29, 2022
    Inventors: Jean Qiu, Peter Y. Li, Leo L. Chan, Jordan Bell
  • Publication number: 20210069696
    Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
    Type: Application
    Filed: February 21, 2019
    Publication date: March 11, 2021
    Inventors: Peter Y. Li, Jean Qiu, Leo L. Chan, Justin R. Hascup, Timothy F. Smith, Todd R. Sobolewski, Nicholas N. Shaw
  • Publication number: 20200385775
    Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
    Type: Application
    Filed: August 22, 2020
    Publication date: December 10, 2020
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan
  • Publication number: 20180128717
    Abstract: The invention provides a method for accurate, efficient and high-throughout measurement of cell viability of diverse biological samples.
    Type: Application
    Filed: June 1, 2016
    Publication date: May 10, 2018
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Olivier Déry, Sarah Kessel, Timothy Smith
  • Publication number: 20180119195
    Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 3, 2018
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan
  • Patent number: 9933415
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: April 3, 2018
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • Patent number: 9342734
    Abstract: The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: May 17, 2016
    Assignee: Nexcelom bioscience LLC
    Inventors: Bo Lin, Peter Y. Li, Jean Qiu, Timothy Smith, Todd Sobolewski, Alnoor Pirani
  • Publication number: 20160025710
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Application
    Filed: July 2, 2015
    Publication date: January 28, 2016
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • Patent number: 9186843
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: November 17, 2015
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu
  • Publication number: 20150232906
    Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
    Type: Application
    Filed: October 9, 2013
    Publication date: August 20, 2015
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan
  • Patent number: 9075790
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: July 7, 2015
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • Publication number: 20150183153
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Application
    Filed: December 31, 2014
    Publication date: July 2, 2015
    Inventors: Leo L. Chan, Jean Qiu
  • Patent number: 8928876
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: January 6, 2015
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu
  • Publication number: 20140347463
    Abstract: The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.
    Type: Application
    Filed: August 6, 2014
    Publication date: November 27, 2014
    Inventors: Bo Lin, Peter Y. Li, Jean Qiu, Timothy Smith, Todd Sobolewski, Alnoor Pirani
  • Patent number: 8883491
    Abstract: The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: November 11, 2014
    Assignee: Nexcelom Bioscience LLC
    Inventors: Bo Lin, Peter Y. Li, Jean Qiu, Timothy Smith, Todd Sobolewski, Alnoor Pirani
  • Publication number: 20130336567
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Application
    Filed: October 20, 2011
    Publication date: December 19, 2013
    Applicant: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • Patent number: 8580578
    Abstract: Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: November 12, 2013
    Assignee: X-Body, Inc.
    Inventors: Brian T. Cunningham, Jane Pepper, Bo Lin, Peter Li, Homer Pien, Jean Qiu
  • Publication number: 20130120747
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 16, 2013
    Inventors: Leo L. Chan, Jean Qiu
  • Publication number: 20110237464
    Abstract: Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.
    Type: Application
    Filed: March 8, 2011
    Publication date: September 29, 2011
    Inventors: Brian T. Cunningham, Peter Li, Jean Qiu, Homer Pien