Abstract: A measuring system includes an elongated sleeve having a compact diameter configured to be delivered over a standard guide wire and able to be flexibly threaded into a tortuous or diseased vascular pathway of a human. Sensor(s), located at a distal end of the sleeve, measure physiological parameter(s) inside the human. The sleeve measuring system has an outer diameter of approximately 20 mils or less and is capable of accommodating the standard guide wire, typically 14 mils in diameter.

Abstract: Reduced bone fracture fixation devices and methods for using the same are provided. Aspects of the reduced bone fracture fixation devices include a body dimensioned to be positioned in a reduced bone fracture, wherein the body has a wedge shape configuration sufficient to exert a force on bone of the reduced bone fracture and maintain reduction of the reduced bone fracture. The devices, kits and methods of the invention find use in a variety of applications, such as in applications in which it is desired to repair a reduced bone fracture.

Abstract: Microcannulae are constructed with multiple components in a composite design, allowing the microcannulae to have varying mechanical and delivery properties that will enable ophthalmic treatments by minimally invasive means. The microcannula includes at least one flexible, tubular communicating element with an outer diameter of 350 microns or less, a proximal connector for introduction of materials, energy or tools. It may also include a reinforcing member attached to the communicating element, which may be designed to create variable stiffness along the length of the microcannula. The microcannula may also include other features such as a signal beacon near the distal tip.

Abstract: Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration.

Abstract: A holding assembly for aesthetically displaying comestibles comprises a retaining structure and a positioning member. The retaining structure allows the user to firmly secure a comestible to the holding assembly. The retaining structure has two different embodiments: one embodiment for softer comestibles with a flat bottom, such as a cupcake, and another embodiment for more rigid comestibles with a round exterior, such as fruit. The first embodiment of the retaining structure is a platform with tines, and the second embodiment of the retaining structure is a hollow hemisphere with one tine. The positioning member is a long shaft that allows the user to position the comestible in a desired location. The top end of the positioning member is used to attached to the bottom of the retaining structure, and the bottom end of the positioning member is used to penetrate into a base in order to situate the holding assembly.

Abstract: Microcannulae are constructed with multiple components in a composite design, allowing the microcannulae to have varying mechanical and delivery properties that will enable ophthalmic treatments by minimally invasive means. The microcannula includes at least one flexible, tubular communicating element with an outer diameter of 350 microns or less, a proximal connector for introduction of materials, energy or tools. It may also include a reinforcing member attached to the communicating element, which may be designed to create variable stiffness along the length of the microcannula. The microcannula may also include other features such as a signal beacon near the distal tip.

Abstract: Reduced bone fracture fixation devices and methods for using the same are provided. Aspects of the reduced bone fracture fixation devices include a body dimensioned to be positioned in a reduced bone fracture, wherein the body includes at least one tension element configured to exert a force on bone of the reduced bone fracture sufficient to maintain reduction of the reduced bone fracture. Aspects of the invention further include kits and methods of using and manufacturing the bone fracture fixation devices. The devices, kits and methods of the invention find use in a variety of applications, such as in applications in which it is desired to repair a reduced bone fracture.

Abstract: A syringe includes a cartridge and a second chamber. The cartridge includes a first chamber, a second end, and a locking mechanism. The second end is movable within the first chamber between a first position and a second position. The locking mechanism has a locked configuration and an unlocked configuration and prevents movement of the second end within the first chamber while in the locked configuration. The locking mechanism includes: a flexible arm having a first end coupled to the second end of the cartridge and a second free end; a tab coupled to the second free end; and a groove in the inner surface of the chamber configured to receive the tab. The cartridge is moveable within the second chamber.

Abstract: Trays comprising a base have a plurality of axial slots adapted to receive buffer or other medical solution containers within the slots. A spring or other compression element at the bottom of the slot is configured to engage a plunger at the bottom of the solution container when present in the slot so that pressure is applied to the contents of the container in order to stabilize the contents while the containers are sterilized at an elevated temperature.

Abstract: The present invention provides for an apparatus and method to excise a tissue sample having a conducting element configured to receive power, an insulating holder coupled to said conducting element, and a connector coupled to said insulating holder for connection to a medical device.

Abstract: Microcannulae are constructed with multiple components in a composite design, allowing the microcannulae to have varying mechanical and delivery properties that will enable ophthalmic treatments by minimally invasive means. The microcannula includes at least one flexible, tubular communicating element with an outer diameter of 350 microns or less, a proximal connector for introduction of materials, energy or tools. It may also include a reinforcing member attached to the communicating element, which may be designed to create variable stiffness along the length of the microcannula. The microcannula may also include other features such as a signal beacon near the distal tip.

Abstract: Occlusion device and method for occluding fallopian tubes comprising at least one looped wire adapted to be deployed within the fallopian tube.

Abstract: Described herein are devices and systems for restoring compression fractured vertebral bodies to a decompressed configuration and methods of restoring compression fractures by bilateral implantation of such devices.

Abstract: Described herein are devices, systems, and methods for treating bone, particularly for restoring bone dimension in compression fractures. Self-expanding stabilization devices for repairing bone may include two or more continuous curvature of bending struts that extend from a central shaft in the deployed configuration. The stabilization device may be attached to an inserter. An inserter may be used to hold the stabilization device in a collapsed delivery configuration so that it can be inserted into bone. In use, the stabilization device may be part of a system or kit for installing the device into a bone region and allowing it to expand to correct a bone fracture.

Abstract: The present invention provides a fluid retention management system that records and displays fluid retention of a patient based on the weight of fluid entering and exiting the patient's body. Scales or other weighing devices are used to weigh the fluid entering and exiting the body so that the corresponding fluid volume may be calculated. The system automatically detects when a fluid container is being replaced. The fluid deficit of the patient is calculated according to the difference between the fluid volume entering the patient and the fluid volume exiting the patient. An operator is able to enter the specific gravity of the fluid and a fluid deficit alarm threshold. If the fluid deficit exceeds the alarm threshold, audible and visual alarms are generated.

Abstract: Apparatus for ascertaining cardiac output of the heart of a patient comprising a control and display module. A venous probe is inserted into a vein in the forearm of the patient and is coupled into the control and display module and provides an electrical signal representing the dissolved oxygen in the venous blood. An arterial probe is inserted into an artery in the forearm of the patient and is coupled into the control and display module and provides an electrical output signal representing the dissolved oxygen in the arterial blood. The control and display module has a visible display that provides a continuous in vivo cardiac output that utilizes an arterial venous oxygen differential equation which includes an adjustment factor for adjusting for venous blood being sampled rather than mixed venous blood in the pulmonary artery of the patient.

Abstract: Apparatus for ascertaining cardiac output of the heart of a patient comprising a control and display module. A venous probe is inserted into a vein in the forearm of the patient and is coupled into the control and display module and provides an electrical signal representing the dissolved oxygen in the venous blood. An arterial probe is inserted into an artery in the forearm of the patient and is coupled into the control and display module and provides an electrical output signal representing the dissolved oxygen in the arterial blood. The control and display module has a visible display that provides a continuous in vivo cardiac output that utilizes an arterial venous oxygen differential equation which includes an adjustment factor for adjusting for venous blood being sampled rather than mixed venous blood in the pulmonary artery of the patient.

Abstract: The present invention provides a fluid retention management system that records and displays fluid retention of a patient based on the weight of fluid entering and exiting the patient's body. Scales or other weighing devices are used to weigh the fluid entering and exiting the body so that the corresponding fluid volume may be calculated. The system automatically detects when a fluid container is being replaced. The fluid deficit of the patient is calculated according to the difference between the fluid volume entering the patient and the fluid volume exiting the patient. An operator is able to enter the specific gravity of the fluid and a fluid deficit alarm threshold. If the fluid deficit exceeds the alarm threshold, audible and visual alarms are generated.

Abstract: The present invention provides a fluid retention management system that records and displays fluid retention of a patient based on the weight of fluid entering and exiting the patient's body. Scales or other weighing devices are used to weigh the fluid entering and exiting the body so that the corresponding fluid volume may be calculated. The system automatically detects when a fluid container is being replaced. The fluid deficit of the patient is calculated according to the difference between the fluid volume entering the patient and the fluid volume exiting the patient. An operator is able to enter the specific gravity of the fluid and a fluid deficit alarm threshold. If the fluid deficit exceeds the alarm threshold, audible and visual alarms are generated.

Abstract: The present invention provides a fluid retention management system that records and displays fluid retention of a patient based on the weight of fluid entering and exiting the patient's body. Scales or other weighing devices are used to weigh the fluid entering and exiting the body so that the corresponding fluid volume may be calculated. The system automatically detects when a fluid container is being replaced. The fluid deficit of the patient is calculated according to the difference between the fluid volume entering the patient and the fluid volume exiting the patient. An operator is able to enter the specific gravity of the fluid and a fluid deficit alarm threshold. If the fluid deficit exceeds the alarm threshold, audible and visual alarms are generated.