Patents by Inventor Jeffrey Shasky

Jeffrey Shasky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme Compositions and Uses Thereof
    Publication number: 20190218584
    Abstract: The present invention relates to enzyme compositions and processes of producing and using the compositions for the saccharification of lignocellulosic material.
    Type: Application
    Filed: March 28, 2019
    Publication date: July 18, 2019
    Applicant: Novozymes A/S
    Inventors: Jeffrey Shasky, Debbie Yaver, Donna Moyer
  • Cellulolytic enzyme compositions and uses thereof
    Publication number: 20190153494
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Application
    Filed: February 6, 2019
    Publication date: May 23, 2019
    Applicant: Novozymes A/S
    Inventors: Jeffrey Shasky, Suchindra Maiyuran, Amanda Fischer
  • Enzyme compositions and uses thereof
    Patent number: 10273515
    Abstract: The present invention relates to enzyme compositions and processes of producing and using the compositions for the saccharification of lignocellulosic material.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: April 30, 2019
    Assignee: Novozymes A/S
    Inventors: Jeffrey Shasky, Debbie Yaver, Donna Moyer
  • Methods for Producing Polypeptides in Protease-Deficient Mutants of Trichoderma
    Publication number: 20190093143
    Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.
    Type: Application
    Filed: December 6, 2018
    Publication date: March 28, 2019
    Applicant: Novozymes, Inc.
    Inventors: Suchindra Maiyuran, Abigail Jang, Kimberly Brown, Sandra Merino, Jeffrey Shasky, Eric Abbate
  • Cellulolytic enzyme compositions and uses thereof
    Patent number: 10233473
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: March 19, 2019
    Assignee: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Suchindra Maiyuran, Amanda Fischer
  • Cellulolytic enzyme compositions and uses thereof
    Publication number: 20190002941
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Application
    Filed: September 5, 2018
    Publication date: January 3, 2019
    Applicant: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Suchindra Maiyuran, Amanda Fischer
  • Cellulolytic enzyme compositions and uses thereof
    Patent number: 10081824
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: September 25, 2018
    Assignee: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Suchindra Maiyuran, Amanda Fischer
  • cellulolytic enzyme compositions and uses thereof
    Patent number: 9970015
    Abstract: The present invention relates to recombinant Trichoderma host cells producing Aspergillus fumigatus cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: May 15, 2018
    Assignee: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Brett McBrayer
  • Methods of Introducing Multiple Expression Constructs Into A Eukaryotic Cell
    Publication number: 20180037897
    Abstract: The present invention relates to methods of introducing multiple expression constructs into a eukaryotic cell, methods of constructing a eukaryotic cell having multiple target loci for expressing multiple heterologous proteins of interest, eukaryotic cells for expressing multiple heterologous proteins of interest, and methods of production of multiple heterologous proteins of interest.
    Type: Application
    Filed: March 9, 2016
    Publication date: February 8, 2018
    Applicant: Novozymes A/S
    Inventors: Qiming Jin, Jeffrey Shasky, Donna Moyer, Abigail Jang, Gloria Muzzi-Erichsen, Cara Kleindienst
  • Methods for producing polypeptides in enzyme-deficient mutants of
    Patent number: 9790532
    Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5?-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: October 17, 2017
    Assignee: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Wendy Yoder
  • Aspergillus Fumigatus Cellulolytic Enzyme Compositions And Uses Thereof
    Publication number: 20170218377
    Abstract: The present invention relates to recombinant Trichoderma host cells producing Aspergillus fumigatus cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Application
    Filed: April 17, 2017
    Publication date: August 3, 2017
    Applicant: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Brett McBrayer
  • Enzyme Compositions and Uses Thereof
    Publication number: 20170204441
    Abstract: The present invention relates to enzyme compositions and processes of producing and using the compositions for the saccharification of lignocellulosic material.
    Type: Application
    Filed: June 4, 2015
    Publication date: July 20, 2017
    Applicant: Novozymes A/S
    Inventors: Jeffrey Shasky, Debbie Yaver, Donna Moyer
  • cellulolytic enzyme compositions and uses thereof
    Patent number: 9663772
    Abstract: The present invention relates to recombinant Trichoderma host cells producing Aspergillus fumigatus cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: May 30, 2017
    Assignee: NOVOZYMES, INC.
    Inventors: Jeffrey Shasky, Brett McBrayer
  • Methods for producing polypeptides in enzyme-deficient mutants of fusarium venentatum
    Publication number: 20170145462
    Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5?-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.
    Type: Application
    Filed: January 27, 2017
    Publication date: May 25, 2017
    Applicant: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Wendy Yoder
  • Methods for producing polypeptides in enzyme-deficient mutants of
    Patent number: 9593342
    Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5?-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: March 14, 2017
    Assignee: NOVOZYMES, INC.
    Inventors: Jeffrey Shasky, Wendy Yoder
  • Cellulolytic enzyme compositions and uses thereof
    Publication number: 20160376622
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Application
    Filed: September 14, 2016
    Publication date: December 29, 2016
    Inventors: Jeffrey Shasky, Suchindra Maiyuran, Amanda Fischer
  • Cellulolytic enzyme compositions and uses thereof
    Patent number: 9476036
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: October 25, 2016
    Assignee: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Amanda Fischer, Suchindra Maiyuran
  • Methods for producing polypeptides in enzyme-deficient mutants of fusarium venentatum
    Publication number: 20160102315
    Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5?-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.
    Type: Application
    Filed: December 18, 2015
    Publication date: April 14, 2016
    Applicant: NOVOZYMES, INC.
    Inventors: Jeffrey Shasky, Wendy Yoder
  • Methods for producing polypeptides in enzyme-deficient mutants of
    Patent number: 9255275
    Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5?-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: February 9, 2016
    Assignee: NOVOZYMES, INC.
    Inventors: Jeffrey Shasky, Wendy Yoder
  • Methods for Producing Polypeptides in Protease-Deficient Mutants of Trichoderma
    Publication number: 20150225761
    Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.
    Type: Application
    Filed: March 19, 2015
    Publication date: August 13, 2015
    Inventors: Suchindra Maiyuran, Abigail Jang, Kimberly Brown, Sandra Merino, Jeffrey Shasky, Eric Abbate