Abstract: Provided herein are compounds of formula (I) and formula (II) that are inhibitors of QPCTL and QPCT: Also provided are pharmaceutical compositions comprising the compounds, and methods for using the compounds for the treatment of disease.

Abstract: Provided herein are inhibitors of PARG, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the PARG inhibitory compounds for the treatment of disease.

Abstract: Dough preparation apparatus and associated methods. The dough preparation apparatus can store and be configured to execute a plurality of dough preparation recipes. In one example, the dough preparation apparatus is configured for thawing or slacking frozen dough and conditioning the dough prior to baking. The dough preparation apparatus facilitates production of baked bread having higher and more consistent quality.

Abstract: Methods and systems are provided for generating an outcome of a previous gameplay. The method includes providing access of a recording of the previous gameplay, the recording is one that was shared by a player for the previous gameplay. The method includes providing an interface that identifies one or more what-if scenarios for the previous gameplay. The one or more what-if scenarios being selected for inclusion into the interface is based on processing the recording of the previous gameplay through a machine learning model to identify what-if scenarios for the user, and options for what-if scenarios are provided to the interface. The method includes enabling the selection of at least one of the what-if scenarios from the options. The selection causes an adjustment to metadata associated with the recording of the previous gameplay. The method includes replaying the recording that was selected using the adjusted metadata to generate the alternative outcome of the previous gameplay.

Abstract: Provided herein are inhibitors of PARG, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the PARG inhibitory compounds for the treatment of disease.

Abstract: Dough preparation apparatus and associated methods. The dough preparation apparatus can store and be configured to execute a plurality of dough preparation recipes. In one example, the dough preparation apparatus is configured for thawing or slacking frozen dough and conditioning the dough prior to baking. The dough preparation apparatus facilitates production of baked bread having higher and more consistent quality.

Abstract: Methods and systems for determining a type of material of an object in a real-world environment are described. One of the methods includes receiving a plurality of sets of audio data based on sounds received from a plurality of objects within a plurality of environments. The method further includes receiving a plurality of sets of input data regarding a plurality of types of materials of the plurality of objects, training an artificial intelligence (AI) model based on the plurality of sets of audio data and the plurality of sets of input data, and applying the AI model to a set of audio data captured from the real-world environment to determine the type of material of the object within the real-world environment to enhance the realism of augmented reality (AR) or virtual reality (VR) video games and applications.

Abstract: The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1? and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

Abstract: Food preparation apparatus and associated methods. In one method, dough is proofed in an oven compartment and then baked in the same oven compartment. Temperature and/or humidity can be controlled during proofing and/or baking cycles. A blower may be used, for example, to exhaust gas to ambient to reduce heat and/or moisture in the compartment. For example, the blower may be used between proofing and baking cycles to prepare an environment in the oven compartment for the baking cycle.

Abstract: A method is provided, including the following operations: monitoring gameplay activity in a plurality of game sessions, wherein the monitoring includes, for each game session, analyzing the gameplay activity in said game session to predict future gameplay activity in said game session; identifying one or more characteristics of a plurality of spectators interacting with a virtual character, wherein each of the spectators interacting with the virtual character accesses, over a network, a channel that is attributed to the virtual character; through the channel, providing access to the spectators to spectate a selected game session that is one of the plurality of game sessions, selected based on the predicted future gameplay activity and based on the characteristics of the plurality of spectators.

Abstract: Food preparation apparatus and associated methods. In one method, dough is proofed in an oven compartment and then baked in the same oven compartment. Temperature and/or humidity can be controlled during proofing and/or baking cycles. A blower may be used, for example, to exhaust gas to ambient to reduce heat and/or moisture in the compartment. For example, the blower may be used between proofing and baking cycles to prepare an environment in the oven compartment for the baking cycle.

Abstract: The present disclosure relates to novel sulfonylurea compounds and related compounds useful in treating a disorder responsive to modulation of cytokines such as IL-1? and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

Abstract: Methods and systems are provided for generating an outcome of a previous gameplay. The method includes providing access of a recording of the previous gameplay, the recording is one that was shared by a player for the previous gameplay. The method includes providing an interface that identifies one or more what-if scenarios for the previous gameplay. The one or more what-if scenarios being selected for inclusion into the interface is based on processing the recording of the previous gameplay through a machine learning model to identify what-if scenarios for the user, and options for what-if scenarios are provided to the interface. The method includes enabling the selection of at least one of the what-if scenarios from the options. The selection causes an adjustment to metadata associated with the recording of the previous gameplay. The method includes replaying the recording that was selected using the adjusted metadata to generate the alternative outcome of the previous gameplay.

Abstract: The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1? and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

Abstract: Methods and systems are provided for generating an outcome of a previous gameplay. The method includes providing access of a recording of the previous gameplay, the recording is one that was shared by a player for the previous gameplay. The method includes providing an interface that identifies one or more what-if scenarios for the previous gameplay. The one or more what-if scenarios being selected for inclusion into the interface is based on processing the recording of the previous gameplay through a machine learning model to identify what-if scenarios for the user, and options for what-if scenarios are provided to the interface. The method includes enabling the selection of at least one of the what-if scenarios from the options. The selection causes an adjustment to metadata associated with the recording of the previous gameplay. The method includes replaying the recording that was selected using the adjusted metadata to generate the alternative outcome of the previous gameplay.

Abstract: The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1? and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

Abstract: Methods and systems are provided for generating an outcome of a previous gameplay. The method includes providing access of a recording of the previous gameplay, the recording is one that was shared by a player for the previous gameplay. The method includes providing an interface that identifies one or more what-if scenarios for the previous gameplay. The one or more what-if scenarios being selected for inclusion into the interface is based on processing the recording of the previous gameplay through a machine learning model to identify what-if scenarios for the user, and options for what-if scenarios are provided to the interface. The method includes enabling the selection of at least one of the what-if scenarios from the options. The selection causes an adjustment to metadata associated with the recording of the previous gameplay. The method includes replaying the recording that was selected using the adjusted metadata to generate the alternative outcome of the previous gameplay.

Abstract: A method is provided, including the following operations: monitoring gameplay activity in a plurality of game sessions, wherein the monitoring includes, for each game session, analyzing the gameplay activity in said game session to predict future gameplay activity in said game session; identifying one or more characteristics of a plurality of spectators interacting with a virtual character, wherein each of the spectators interacting with the virtual character accesses, over a network, a channel that is attributed to the virtual character; through the channel, providing access to the spectators to spectate a selected game session that is one of the plurality of game sessions, selected based on the predicted future gameplay activity and based on the characteristics of the plurality of spectators.

Abstract: The present disclosure relates to novel sulfonylurea compounds and related compounds useful in treating a disorder responsive to modulation of cytokines such as IL-1? and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

Abstract: The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1? and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.