Patents by Inventor Jeffrey T. Abbott

Jeffrey T. Abbott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210371846
    Abstract: Methods and systems for stimulating and monitoring electrogenic cells are described. Some systems for stimulating electrogenic cells are based on the injection of electric currents into the cells via electrodes connected to the cells. Such stimulators may comprise an impedance element having an input terminal and an output terminal coupled to an electrode, and a voltage follower coupled between the input terminal and the output terminal of the impedance element, the voltage follower being configured to maintain a substantially constant voltage between the input terminal and the output terminal of the impedance element. The impedance element may comprise one or more switched capacitors at least in some embodiments. In some embodiments, the voltage follower may be implemented using a source follower.
    Type: Application
    Filed: July 6, 2018
    Publication date: December 2, 2021
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Donhee Ham, Jeffrey T ABBOTT, Hongkun PARK, Wenxuan WU
  • Publication number: 20210187280
    Abstract: The present invention generally relates to nanowires. In one aspect, the present invention is generally directed to systems and methods of individually addressing nanowires on a surface, e.g., that are substantially upstanding or vertically-oriented with respect to the surface. In some cases, one or more nanowires may be individually addressed using various integrated circuit (“IC”) technologies, such as CMOS. For example, the nanowires may form an array on top of an active CMOs integrated circuit.
    Type: Application
    Filed: January 8, 2021
    Publication date: June 24, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Hongkun Park, Donhee Ham, Jeffrey T. Abbott, Ling Qin, Marsela Jorgolli, Tianyang Ye
  • Publication number: 20200292482
    Abstract: Methods and systems for monitoring the activity of electrogenic networks are described. One representative system includes an array of electrode coupled to an analyzer having a stimulator and a receiver. The electrode is placed in contact with an electrogenic cell. The electrodes can be shaped as nanowires, tubes, cavities and/or cones. The analyzer may be configured to operate in a voltage stimulation mode, in which the cells are stimulated via voltages and monitored via current, or in a current stimulation mode, in which the cells are stimulated via currents and monitored via voltages. The analyzers may be arranged as single-stage amplifiers, and may include a feedback loop shared between the stimulation signal path and the sensing signal path. The feedback loop may be arranged to provide overlapping stimulation and sensing of the electrogenic network's cells.
    Type: Application
    Filed: October 30, 2018
    Publication date: September 17, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Donhee Ham, Hongkun Park, Keith Krenek, Tianyang Ye, Jeffrey T. Abbott, Wenxuan Wu