Patents by Inventor Jeffrey W. Speakman

Jeffrey W. Speakman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180125620
    Abstract: A method of treating a tubular medical device with a biomolecule comprises the steps of: a) providing a polyolefin tubular substrate forming a tubular medical device; b) cleaning the tubular polyolefin substrate; c) exposing the tubular polyolefin substrate to a reactive gas containing at least one of acrylic acid and siloxane and to plasma energy to yield a plasma-deposited coating on at least one surface of the tubular polyolefin substrate; and d) attaching a biomolecule to the polyolefin substrate following formation of the plasma-deposited coating on at least one surface of the tubular polyolefin substrate, and wherein the biomolecule is at least one of an antibacterial agent, antimicrobial agent, anticoagulant, heparin, antithrombotic agent, platelet agent, anti-inflammatory, enzyme, catalyst, hormone, growth factor, drug, vitamin, antibody, antigen, protein, nucleic acid, dye, a DNA segment, an RNA segment, protein, and peptide.
    Type: Application
    Filed: July 3, 2017
    Publication date: May 10, 2018
    Inventors: Ali Hussain, Linda Cahalan, Greg Johnson, Mark Gartner, Patrick Cahalan, Brian J. Fill, Jeffrey W. Speakman
  • Patent number: 9693841
    Abstract: A variety of medical devices including staples sutures and dental floss with surface treatment on at least one tissue-facing surface to improve biologic function such as to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 4, 2017
    Assignee: ENSION, INC.
    Inventors: Ali Hussain, Linda Cahalan, Greg Johnson, Mark Gartner, Patrick Cahalan, Brian J Fill, Jeffrey W. Speakman
  • Patent number: 9211369
    Abstract: An integrated blood pump oxygenator comprises an impeller housing supporting an impeller with an annular hydrogel impeller packing material adjacent the bearings and around the shaft of the impeller. The oxygenator including a rollover outlet in the form of an annular chamber extending around a center pump housing member; and further including an annular chamber within an annular array of hollow fiber membranes in fluid communication with the annular chamber extending from the impeller around the center pump housing; wherein the annular chamber provides substantially perpendicular radial outward cross flow across the membranes.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: December 15, 2015
    Assignee: Ension, Inc
    Inventors: Mark J Gartner, Brian J Fill, Patrick Cahalan, Linda Cahalan, Jeffrey W. Speakman
  • Publication number: 20140288592
    Abstract: A variety of medical devices including staples sutures and dental floss with surface treatment on at least one tissue-facing surface to improve biologic function such as to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 25, 2014
    Applicant: ENSION, INC.
    Inventors: Ali HUSSAIN, Linda Cahalan, Greg Johnson, Mark Gartner, Patrick Cahalan, Brian J. Fill, Jeffrey W. Speakman
  • Publication number: 20130110137
    Abstract: A variety of polymeric synthetic hernia mesh prosthesis with surface treatment on at least one tissue-facing surface to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment. The synthetic hernia mesh may be formed of monofilament or multifilament polypropylene or polyester, and may be formed as a multi-layer prosthesis with an outer layer formed of a polymeric synthetic hernia mesh with surface treatment to control tissue adhesion coupled to one or more polymeric synthetic hernia meshes without such surface treatments.
    Type: Application
    Filed: October 1, 2012
    Publication date: May 2, 2013
    Applicant: Ension, Inc.
    Inventors: Enrico Nicolo, Linda Cahalan, Greg Johnson, Mark Gartner, Patrick Cahalan, Brian J Fill, Ali HUSSAIN, Jeffrey W. Speakman
  • Publication number: 20080281341
    Abstract: A method for endothelial keratoplasty donor tissue transport and delivery to a recipient's eye, such as in DLEK, DSEK and DSAEK procedures, comprises the steps of: attaching endothelial keratoplasty donor tissue to a tissue holder, wherein the attachment between the tissue holder and the donor tissue is not on the endothelial layer of the endothelial keratoplasty donor tissue; placing the tissue holder and the attached donor tissue within a surrounding insertion tip; transporting the insertion tip to a position adjacent an access opening in the recipient's eye; inserting the tissue holder with the attached donor tissue through the opening and extending the tissue holder from within the insertion tip to position the donor tissue within the recipient's eye; and separating the attached donor tissue from the tissue holder with the tissue holder within the recipient's eye. An associated apparatus is disclosed.
    Type: Application
    Filed: May 12, 2008
    Publication date: November 13, 2008
    Applicants: ENSION, INC., UPMC
    Inventors: Jason Miller, Jeffrey W. Speakman, Ahmed Al-Ghoul, Deepinder Dhaliwal