Patents by Inventor Jeng Shong Chen

Jeng Shong Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10934330
    Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: March 2, 2021
    Assignee: Syngenta Participations AG
    Inventors: Yan Gao, Jared Conville, Jeng Shong Chen
  • Publication number: 20210024592
    Abstract: This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.
    Type: Application
    Filed: October 9, 2020
    Publication date: January 28, 2021
    Applicant: Syngenta Crop Protection AG
    Inventors: Milan JUCOVIC, Renshui LIU, Richard SESSLER, Guo-Qing TANG, Jeng Shong CHEN
  • Patent number: 10836801
    Abstract: This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: November 17, 2020
    Assignee: Syngenta Crop Protection AG
    Inventors: Milan Jucovic, Renshui Liu, Richard Sessler, Guo-Qing Tang, Jeng Shong Chen
  • Patent number: 10604757
    Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules that capable of interfering with pest histone genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: March 31, 2020
    Assignee: Syngenta Participations AG
    Inventors: Kevin V. Donohue, Renshui Liu, Jeng Shong Chen
  • Publication number: 20190359994
    Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, dsRNA molecules that capable of interfering with pest IAP genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.
    Type: Application
    Filed: August 13, 2019
    Publication date: November 28, 2019
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Kevin Donohue, Renshui Liu, Jeng Shong Chen
  • Publication number: 20190194644
    Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.
    Type: Application
    Filed: December 4, 2018
    Publication date: June 27, 2019
    Applicant: Syngenta Participations AG
    Inventors: Yan GAO, Jared CONVILLE, Jeng Shong CHEN
  • Publication number: 20190112343
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: December 7, 2018
    Publication date: April 18, 2019
    Applicant: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes
  • Patent number: 10239921
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: March 26, 2019
    Assignee: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes, Frederick Walters
  • Patent number: 10196633
    Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: February 5, 2019
    Assignee: Syngenta Participations AG
    Inventors: Yan Gao, Jared Conville, Jeng Shong Chen
  • Patent number: 10167323
    Abstract: Improved compositions and methods for controlling pests are disclosed. In particular, nucleic acid molecules encoding novel engineered Cry1Ba (eCry1Ba) proteins having improved toxicity to lepidopteran insect pests are provided. By substituting at least one amino acid in domain I of a Cry1Ba protein an engineered Cry1Ba protein having substantially altered insecticidal properties is designed. Further, methods of making and using the ecry1Ba nucleic acid sequences, for example in transgenic plants to express eCry1B proteins to confer protection from insect damage are disclosed.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: January 1, 2019
    Assignee: Syngenta Participations AG
    Inventors: Yan Gao, Jared Conville, Jeng Shong Chen
  • Publication number: 20180346528
    Abstract: This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Applicant: Syngenta Participations AG
    Inventors: Milan JUCOVIC, Renshui LIU, Richard SESSLER, Guo-Qing TANG, Jeng Shong CHEN
  • Publication number: 20180291397
    Abstract: Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide sequences encoding the pesticidal polypeptide can be used to transform various prokaryotic and eukaryotic organisms, which organisms can be used to produce the pesticidal polypeptides. The recombinant organisms and/or the polypeptides produced by the recombinant organisms can be used to control pests in various environments.
    Type: Application
    Filed: June 15, 2018
    Publication date: October 11, 2018
    Applicant: Syngenta Participations AG
    Inventors: Mikyong LEE, Jeng Shong CHEN, Jared CONVILLE, Narendra PALEKAR, Cheryl Marie DEFONTES
  • Publication number: 20180249690
    Abstract: Artificially selected strains of insects from the genus Spodoptera exhibiting resistance to a Bacillus thuringiensis derived Vip3A protein are described. Methods for various uses of these strains are also described.
    Type: Application
    Filed: May 12, 2016
    Publication date: September 6, 2018
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Julio Fatoretto, Zhimou Wen, Phillip Matthews, Jeng Shong Chen
  • Publication number: 20180216105
    Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules that capable of interfering with pest histone genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.
    Type: Application
    Filed: November 17, 2015
    Publication date: August 2, 2018
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Kevin V. Donohue, Renshui Liu, Jeng Shong Chen
  • Patent number: 10023876
    Abstract: Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide sequences encoding the pesticidal polypeptide can be used to transform various prokaryotic and eukaryotic organisms, which organisms can be used to produce the pesticidal polypeptides. The recombinant organisms and/or the polypeptides produced by the recombinant organisms can be used to control pests in various environments.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: July 17, 2018
    Inventors: Mikyong Lee, Jeng Shong Chen, Cheryl Marie De Fontes, Jared Conville, Narendra Palekar
  • Patent number: 9861105
    Abstract: Transgenic plants expressing a Vip3 protein have been found to be efficacious against plant-infesting nematodes. Disclosed are methods of controlling nematode populations using transgenic plants expressing Vip3 protein.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: January 9, 2018
    Assignee: Syngenta Participations AG
    Inventors: Xiang Huang, Jeng Shong Chen
  • Publication number: 20170283814
    Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, dsRNA molecules that capable of interfering with pest IAP genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.
    Type: Application
    Filed: April 17, 2017
    Publication date: October 5, 2017
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Kevin Donohue, Renshui Liu, Jeng Shong Chen
  • Patent number: 9657293
    Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, dsRNA molecules that capable of interfering with pest IAP genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: May 23, 2017
    Assignee: Sygenta Participations AG
    Inventors: Kevin Donohue, Renshui Liu, Jeng Shong Chen
  • Publication number: 20170058008
    Abstract: This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.
    Type: Application
    Filed: February 26, 2015
    Publication date: March 2, 2017
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Renshui Liu, Milan Jucovic, Richard Sessler, Guo-Qing Tang, Jeng Shong Chen
  • Patent number: 9522937
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: December 20, 2016
    Assignee: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes, Frederick Walters