Publication number: 20040048253
Abstract: The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.
Type:
Application
Filed:
June 5, 2003
Publication date:
March 11, 2004
Inventors:
Scott R. Panzer, Peter A. Spiro, Steven C. Banville, Purvi Shah, Michael S. Chalup, Simon C Chang, Alice J. Chen, Steven A. D'Sa, Stefan Amshey, Christopher E. Dahl, Tam C. Dam, Susan E. Daniels, Gerard E. Dufour, Vincent Flores, Willy T. Fong, Lila B. Greenawalt, Jennifer L. Jackson, Anissa L. Jones, Tommy F. Liu, Ann M. Roseberry Lincoln, Bruce H. Rosen, Frank D. Russo, Theresa K. Stockdreher, Abel Daffo, Rachel J. Wright, Pierre E. Yap, Jimmy Y. Yu, Diana L. Bradley, Shawn R. Bratcher, Wensheng Chen, Howard J. Cohen, David M. Hodgson, Stephen E. Lincoln, Stuart E. Jackson
Publication number: 20040018185
Abstract: The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
Type:
Application
Filed:
May 19, 2003
Publication date:
January 29, 2004
Inventors:
Henry Yue, Ammena R. Gandhi, Catherine M. Tribouley, Liam Kearney, Jennifer A. Griffin, Danniel B. Nguyen, Olga Bandman, Dyung Aina M. Lu, Preeti G. Lal, Neil Burford, Farrah A. Khan, Narinder K. Chawla, Monique G. Yao, Chandra S. Arvizu, John D. Burrill, Gregory A. Marcus, Kurt A. Zingler, Shirley A. Recipon, Yan Lu, Jennifer L. Policky, Michael B. Thornton, Y Tom Tang, April J.A. Hafalia, Vicki S. Elliott, Mariah r. Baughn, Roderick T. Walsh, Jayalaxmi Ramkumar, Mark L. Borowsky, Janice K. Au-Young, Jennifer L. Jackson, Rajagopal Gururajan
Publication number: 20030216310
Abstract: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
Type:
Application
Filed:
May 8, 2003
Publication date:
November 20, 2003
Inventors:
Michael B. Thornton, Narinder K. Chawla, Henry Yue, Danniel B. Nguyen, Preeti G. Lal, Ameena R. Gandhi, Catherine M. Tribouley, Monique G. Yao, Jayalaxmi Ramkumar, Janice K. Au-Young, Yan Lu, Y. Tom Tang, Yalda Azimzai, Christopher M. Bruns, Jennifer A. Griffin, Junming Yang, Mariah R. Baughn, Madhusudan M. Sanjanwala, Brigitte E. Raumann, Ernestine A. Lee, April J.A. Hafalia, Barrie D. Greene, Farrah A. Khan, Liam Kearney, Vicki S. Elliott, Jeffrey J. Seilhamer, Jennifer L. Policky, Mark L. Borowsky, Li Ding, Dyung Aina M. Lu, Jennifer L. Jackson
Publication number: 20030211093
Abstract: The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associatedd withd abberant expression of PKIN.
Type:
Application
Filed:
January 15, 2003
Publication date:
November 13, 2003
Inventors:
Henry Yue, Farrah A Khan, Rajagopal Gururajan, April J A Hafalia, Narinder K Chawla, Chandra S Arvizu, Jayalaxmi Ramkumar, Ameena R Gandhi, Jennifer L Policky, Mariah R Baughn, Catherine M Tribouley, Michael B Thornton, Olga Bandman, Danniel B Nguyen, Yan Lu, Neil Burford, Preeti G Lal, Li Ding, Monique G Yao, Vicki S Elliott, Shirley A Recipon, Liam Kearney, Dyung Aina M Lu, Sara R Greenwald, Y Tom Tang, Yuming Xu, Roderick T Walsh, Kimberly J Gietzen, Junming Yang, Jennifer L Jackson