Patents by Inventor Jennifer Thurmond

Jennifer Thurmond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8722384
    Abstract: The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to ?-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: May 13, 2014
    Assignees: Calgene LLC, Abbott Laboratories
    Inventors: Deborah Knutzon, Pradip Mukerji, Yung-Sheng Huang, Jennifer Thurmond, Sunita Chaudhary, Amanda Eun-Yeong Leonard
  • Patent number: 8143486
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: March 27, 2012
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Tapas Das, Yung-Sheng Huang, Jennifer Thurmond, Suzette L. Pereira
  • Patent number: 8143383
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: March 27, 2012
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Tapas Das, Yung-Sheng Huang, Jennifer Thurmond, Suzette L. Pereira
  • Publication number: 20110256260
    Abstract: The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid linoleic acid, linoleic acid to ?-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
    Type: Application
    Filed: March 30, 2009
    Publication date: October 20, 2011
    Applicants: Calgene LLC, Abbott Laboratories
    Inventors: Deborah Knutzon, Pradip Mukerji, Yung-Sheng Huang, Jennifer Thurmond, Sunita Chaudhary, Amanda Leonard
  • Publication number: 20110003360
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Application
    Filed: September 9, 2010
    Publication date: January 6, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Pradip Mukerji, Yung-Sheng Huang, Tapas Das, Jennifer Thurmond, Suzette L. Pereira
  • Publication number: 20110003351
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Application
    Filed: September 9, 2010
    Publication date: January 6, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Pradip Mukerji, Yung-Sheng Huang, Tapas Das, Jennifer Thurmond, Suzette L. Pereira
  • Publication number: 20100310710
    Abstract: The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid linoleic acid, linoleic acid to ?-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
    Type: Application
    Filed: March 30, 2009
    Publication date: December 9, 2010
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Deborah Knutzon, Pradip Mukerji, Yung-Sheng Huang, Jennifer Thurmond, Sunita Chaudhary, Amanda Eun-Yeong Leonard
  • Patent number: 7745694
    Abstract: The present invention relates to compositions and methods for preparing polyunsaturated long chain fatty acids in plants, plant parts and plant cells, such as leaves, roots, fruits and seeds. Nucleic acid sequences and constructs encoding fatty acid desaturases, including ?5-desaturases, ?6-desaturases and ?12-desaturases, are used to generate transgenic plants, plant parts and cells which contain and express one or more transgenes encoding one or more desaturases. Expression of the desaturases with different substrate specificities in the plant system permit the large scale production of polyunsaturated long chain fatty acids such as docosahexaenoic acid, eicosapentaenoic acid, ?-linolenic acid, gamma-linolenic acid, arachidonic acid and the like for modification of the fatty acid profile of plants, plant parts and tissues. Manipulation of the fatty acid profiles allows for the production of commercial quantities of novel plant oils and products.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: June 29, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Deborah Knutzon, Pradip Mukerji, Yung-Sheng Huang, Jennifer Thurmond, Sunita Chaudhary, Amanda Eun-Yeong Leonard
  • Publication number: 20090265798
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Application
    Filed: May 7, 2007
    Publication date: October 22, 2009
    Inventors: Pradip Mukerji, Yung-Sheng Huang, Tapas Das, Jennifer Thurmond, Suzette L. Pereira
  • Patent number: 7531347
    Abstract: The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to ?-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: May 12, 2009
    Assignees: Abbott Laboratories, Calgene, LLC
    Inventors: Deborah Knutzon, Pradip Mukerji, Yung-Sheng Huang, Jennifer Thurmond, Sunita Chaudhary, Amanda Eun-Yeong Leonard
  • Patent number: 7241619
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: July 10, 2007
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Yung-Sheng Huang, Tapas Das, Jennifer Thurmond, Suzette L. Pereira
  • Patent number: 7220897
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “?4-desaturase”). In particular, ?4-desaturase may be utilized, for example, in the conversion of adrenic acid to ?6-docosapentaenoic acid and in the conversion of ?3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: May 22, 2007
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Tapas Das, Amanda Eun-Yeong Leonard, Suzette L. Pereira
  • Patent number: 7208297
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “?4-desaturase”). In particular, ?4-desaturase may be utilized, for example, in the conversion of adrenic acid to ?6-docosapentaenoic acid and in the conversion of ?3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: April 24, 2007
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Tapas Das, Amanda Eun-Yeong Leonard, Suzette L. Pereira
  • Patent number: 7205134
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “?4-desaturase”). In particular, ?4-desaturase may be utilized, for example, in the conversion of adrenic acid to ?6-docosapentaenoic acid and in the conversion of ?3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: April 17, 2007
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Tapas Das, Amanda Eun-Yeong Leonard, Suzette L. Pereira
  • Patent number: 7067285
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “?5-desaturase”) and at carbon 6 (i.e., “?6-desaturase”) and to uses thereof. In particular, ?5-desaturase may be utilized, for example, in the conversion of dihomo-?-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to ?-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: June 27, 2006
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Yung-Sheng Huang, Tapas Das, Jennifer Thurmond, Amanda Eun-Yeong Leonard, Suzette L. Pereira
  • Patent number: 7045683
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “?4-desaturase”). In particular, ?4-desaturase may be utilized, for example, in the conversion of adrenic acid to ?6-docosapentaenoic acid and in the conversion of ?3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: May 16, 2006
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Tapas Das, Amanda Eun-Yeong Leonard, Suzette L. Pereira
  • Publication number: 20060048244
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 6 (i.e., “?6-desaturase”). In particular, ?6-desaturase may be utilized, for example, in the conversion of linoleic acid to ?-linolenic acid and in the conversion of ?-linolenic acid stearidonic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Application
    Filed: September 1, 2004
    Publication date: March 2, 2006
    Inventors: Pradip Mukerji, Yung-Sheng Huang, Amanda Leonard, Suzette Pereira, Jennifer Thurmond
  • Patent number: 6913916
    Abstract: The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated acids (i.e., “elongases”) and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogama linolenic acid (DGLA) and in the conversion of DGLA or 20:4n-3 to eicosapentaenoic acid (EPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachiodonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ?6-docosapentaenoic acid or ?3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: July 5, 2005
    Assignee: Abbott Laboratories
    Inventors: Pradip Mukerji, Tapas Das, Yung-Sheng Huang, Jennifer M. Parker-Barnes, Amanda Eun-Yeong Leonard, Jennifer Thurmond
  • Publication number: 20050005328
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “?4-desaturase”). In particular, ?4-desaturase may be utilized, for example, in the conversion of adrenic acid to ?6-docosapentaenoic acid and in the conversion of ?3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Application
    Filed: August 6, 2004
    Publication date: January 6, 2005
    Inventors: Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Tapas Das, Amanda Leonard, Suzette Pereira
  • Publication number: 20050005329
    Abstract: The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “?4-desaturase”). In particular, ?4-desaturase may be utilized, for example, in the conversion of adrenic acid to ?6-docosapentaenoic acid and in the conversion of ?3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
    Type: Application
    Filed: August 6, 2004
    Publication date: January 6, 2005
    Inventors: Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Tapas Das, Amanda Leonard, Suzette Pereira