Patents by Inventor Jens Vinge Nygaard

Jens Vinge Nygaard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160310640
    Abstract: The present invention relates to a three-dimensional biocompatible scaffold capable of supporting cell activities, such as growth and differentiation, the scaffold comprising a first biocompatible material and a second biocompatible material, said second material filling a substantial part of the first voids shaped by said first biocompatible material, wherein the scaffold has a diameter of less than 500 ?m.
    Type: Application
    Filed: December 10, 2014
    Publication date: October 27, 2016
    Inventors: Jens Vinge Nygaard, Christian Perti
  • Publication number: 20140329323
    Abstract: A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold. The scaffold design can be understood as a hierarchically organised structure. At the micron to submicron length scale a top/down manufacturing approach is used to make a structure that will constitute the frame into which a bottom/up processing approach is applied to form an open porous scaffold with specific nano sized features. The advantage of this hierarcially organised design is that benefits can be drawn independently from both the micron and the nano sized structures, promoting specific cell activities and providing sufficient mechanical compliance.
    Type: Application
    Filed: July 16, 2014
    Publication date: November 6, 2014
    Inventors: Jens Vinge Nygaard, Lea Bjerre, Cody Eric Bünger, Flemming Besenbacher
  • Patent number: 8815276
    Abstract: A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold. The scaffold design can be understood as a hierarchically organised structure. At the micron to submicron length scale a top/down manufacturing approach is used to make a structure that will constitute the frame into which a bottom/up processing approach is applied to form an open porous scaffold with specific nano sized features. The advantage of this hierarchically organised design is that benefits can be drawn independently from both the micron and the nano sized structures, promoting specific cell activities and providing sufficient mechanical compliance.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: August 26, 2014
    Assignees: Aarhus Universitet, Region Midtjylland
    Inventors: Jens Vinge Nygaard, Lea Bjerre, Cody Eric Bünger, Flemming Besenbacher
  • Patent number: 8741631
    Abstract: A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: June 3, 2014
    Assignees: Aarhus Universitet, Region Midtjylland
    Inventors: Dang Quang Svend Le, Jens Vinge Nygaard, Morten Foss, Flemming Besenbacher, Cody Bünger
  • Publication number: 20130211543
    Abstract: A three-dimensional hybrid scaffold capable of supporting cell activities such as growth and differentiation, and capable of controlled release of active pharmaceutical ingredients, characterized in that the scaffold comprises a first and a second biocompatible material, said first material shaped as a framework forming one or more open networks of voids, said second material comprising an ion exchange material, said ion exchange material being loaded with one or more active pharmaceutical ingredients.
    Type: Application
    Filed: October 7, 2011
    Publication date: August 15, 2013
    Applicants: REGION MIDTJYLLAND, AARHUS UNIVERSITET
    Inventors: Muwan Chen, Dang Quang Sven Le, San Hein, Jørgen Kjems, Cody Eric Bünger, Jens Vinge Nygaard
  • Publication number: 20120171718
    Abstract: A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel.
    Type: Application
    Filed: June 3, 2010
    Publication date: July 5, 2012
    Applicants: REGION MIDTJYLLAND, AARHUS UNIVERSITET
    Inventors: Dang Quang Svend Le, Jens Vinge Nygaard, Morten Foss, Flemming Besenbacher, Cody Bünger
  • Publication number: 20120128739
    Abstract: A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold. The scaffold design can be understood as a hierarchically organised structure. At the micron to submicron length scale a top/down manufacturing approach is used to make a structure that will constitute the frame into which a bottom/up processing approach is applied to form an open porous scaffold with specific nano sized features. The advantage of this hierarchically organised design is that benefits can be drawn independently from both the micron and the nano sized structures, promoting specific cell activities and providing sufficient mechanical compliance.
    Type: Application
    Filed: June 25, 2010
    Publication date: May 24, 2012
    Applicants: REGION MIDTJYLLAND, AARHUS UNIVERSITET
    Inventors: Jens Vinge Nygaard, Lea Bjerre, Cody Eric Bunger, Flemming Besenbacher
  • Publication number: 20100298719
    Abstract: A method for calculating pressures in a fluid streaming through a tube section from an upstream end to a downstream end of the tube section, the method comprising scanning the tube section with a scanner and providing a plurality of 2D scanning images along the tube section with an inlet and at least two arms, by a computer program on the basis of the 2D images automatically N calculating a 3D image of the tube section by using interpolating between the 2D images, by a computer program performing a 2D sectional image cut through the 3D image, the image cut following the fluid stream, calculating in the sectional image cut a fluid pressure distribution along multiple locations inside the tube on the basis of given boundary conditions, the boundary conditions including fluid velocity or fluid pressure at the upstream end.
    Type: Application
    Filed: October 31, 2008
    Publication date: November 25, 2010
    Inventors: Samuel Alberg Kock, Jens Vinge Nygaard, Flemming Besenbacher, Won Yong Kim