Patents by Inventor Jeong-Woo Seo
Jeong-Woo Seo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240101684Abstract: The present invention relates to: an anti-fibroblast growth factor receptor 3 (FGFR3) antibody or antigen-binding fragment thereof; a nucleic acid encoding same; a recombinant expression vector comprising the nucleic acid; a host cell transfected with the recombinant expression vector; a method for producing the antibody or antigen-binding fragment thereof; a bispecific or multispecific antibody comprising the antibody or antigen-binding fragment thereof; an immune cell-engaging bispecific or multispecific antibody comprising an scFv comprising an scFv of the antibody and a second binding domain comprising at least one scFv of an antibody that binds to an immune cell-activating antigen; an antibody-drug conjugate (ADC) in which the antibody or the antigen-binding fragment thereof is bound to a drug; a chimeric antigen receptor (CAR) comprising the scFv of the anti-FGFR3 antibody as an antigen-binding site of an extracellular domain; an immune cell having the chimeric antigen receptor introduced thereinto; a cType: ApplicationFiled: January 5, 2022Publication date: March 28, 2024Inventors: Do-Hyun NAM, Yeup YOON, Byeongkwi MIN, Yun-Jee SEO, Jeong-Woo OH
-
Publication number: 20240000680Abstract: The present invention relates to an enzyme for producing hydroxy derivatives of polyunsaturated fatty acids, a method for producing hydroxy derivatives of polyunsaturated fatty acids using the same, and an SPMs complex composition containing the hydroxy derivatives of polyunsaturated fatty acids. The enzyme may produce hydroxy derivatives of polyunsaturated fatty acids in a single reaction, and thus may be very usefully used for in vitro production. In addition, the SPMs complex composition containing the hydroxy derivatives of polyunsaturated fatty acids promotes collagen production, inhibits the production of NO and expression of TNF-? and IL-6, increases the expression of filaggrin and loricrin, and thus may be usefully used for preventing or alleviating skin aging or wrinkles, strengthening skin barrier, or preventing, alleviating or treating skin diseases comprising atopic dermatitis.Type: ApplicationFiled: December 6, 2019Publication date: January 4, 2024Inventors: Jeong Woo SEO, Jong Jae Yl, Sun Yeon HEO, JungHyun JU, Chul Ho KIM, Baek Rock OH, Gil Yong LEE, Kyung Min LEE, Hee Won CHO
-
Publication number: 20230320233Abstract: A spin-orbit-torque (SOT)-based magnetic sensor is provided. The magnetic sensor includes a substrate, an electrode layer formed on the substrate, and a pair of first and second sensing elements stacked on the substrate so as to be connected to the electrode layer, wherein directions of respective currents flowing through the first and second sensing elements via the electrode layer are opposite to each other.Type: ApplicationFiled: June 16, 2022Publication date: October 5, 2023Applicants: HYUNDAI MOTOR COMPANY, KIA CORPORATION, IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)Inventors: Ji-Sung Lee, Su-Jung Noh, Han-Saem Lee, Joon-Hyun Kwon, Jeong-Woo Seo, Jeong-Hun Shin, Jin-Pyo Hong
-
Publication number: 20220370205Abstract: The present invention relates to an animal femoral implant and, more specifically, to an animal femoral implant, which may enable artificial hip joint replacement for animals, may enable the implant to be firmly fixed to the animal femur by spontaneous bone growth of the animal, thereby preventing complications such as aseptic dissociation and bone resorption around the cement, which may occur when using bone cement, and may cause a porous part, which has relatively low strength due to a plurality of pores formed therein, to be protected by a frame part, which has relatively high strength due to a solid face formed therein, thereby preventing damage to the porous part in which the edge thereof is broken or bent by friction with the bone or by an external force in the process of inserting the femur implant into the animal femur and eliminating a problem in that porous particles that may be generated when the porous part is damaged penetrate into blood vessels and the like to cause various inflammatory reactionType: ApplicationFiled: October 15, 2020Publication date: November 24, 2022Inventors: Jeong-Woo Seo, Bo-Kyun Sim
-
Publication number: 20220370337Abstract: The present invention relates to a composition including a Tremella fuciformis culture medium extract. The Tremella fuciformis culture medium extract according to the present invention not only has low cytotoxicity but also has the effects of increasing the production amount of a moisturizing factor and the production amounts of collagen and collagen fibers and inhibiting in vivo active oxygen species, and thus can be utilized as a natural product-derived moisturizing, anti-wrinkle, and anti-oxidant functional material, and can be applied in various ways in the beauty and food fields for skin condition improvement.Type: ApplicationFiled: September 29, 2020Publication date: November 24, 2022Inventors: Hyun Sook Yeom, Won Bo Oh, Ji Hye Kim, Hye Ja Lee, Jin Oh Park, Ji Won Lee, Chul Ho Kim, Baek Rock Oh, Min Soo Kim, Sun Yeon Heo, Jeong Woo Seo
-
Patent number: 11446234Abstract: Lactobacilus reuteri CH53 strain has high productivity of 1,3-propanediol from glycerol and uses thereof. It is confirmed that Lactobacilus reuteri CH53 strain is capable of converting at very high yield glycerol or crude glycerol to high-concentration 1,3-propanediol. Since Lactobacilus reuteri CH53 strain of the present invention capable of producing large amounts of 1,3-propanediol is one kind of lactic acid bacteria that are safe for humans (GRAS, Generally Recognized As Safe), when it is used for producing 1,3-propanediol from crude glycerol, it would be very advantageously used, unlike existing GMO strains, in related industries from the viewpoint of safety or environment and also providing an advantage of recycled use of resources.Type: GrantFiled: November 27, 2017Date of Patent: September 20, 2022Assignee: ACTIVON CO., LTD.Inventors: Chul Ho Kim, Baek Rock Oh, Jeong-Woo Seo, Sun-Yeon Heo, Jung Hyun Ju
-
Publication number: 20220138770Abstract: There is disclosed a method for analyzing a sales conversation based on voice recognition. The disclosed method comprises obtaining voice information about a sales conversation between a sales representative and a customer, converting the voice information into text, extracting at least one of a keyword and a sentence corresponding to each of a plurality of business items from the text, extracting analysis information for each of the plurality of business items based on at least one of the keyword and the sentence, and calculating an evaluation score for each of the plurality of business items based on the analysis information for each of the plurality of business items.Type: ApplicationFiled: January 14, 2022Publication date: May 5, 2022Inventors: Jin Kook LEE, Se Myung BAEK, Dae Young HONG, Jeong Woo SEO
-
Publication number: 20220023053Abstract: The present disclosure relates to an animal knee joint implant that reflects an anatomical structure of an animal. More particularly, the present disclosure relates to an animal knee joint implant that reflects the anatomical structure of an animal, wherein the knee joint implant is capable of being used for diseases, which are accompanied by bone loss, damage to surrounding muscles, ligaments, and the like and are thus more complex than general knee joint diseases such as rheumatoid arthritis and degenerative arthritis, and wherein the animal knee joint implant is capable of reinforcing stability against varus and valgus as well as stability against flexion and extension, and capable of easily complementing gaps that may occur when the bones of a joint are cut.Type: ApplicationFiled: December 10, 2019Publication date: January 27, 2022Inventors: Jung-Sung Kim, Jeong-Woo Seo, Bo-Kyun Sim
-
Publication number: 20210040518Abstract: The present invention relates to a novel enzyme capable of producing multi-hydroxy derivatives from polyunsaturated fatty acids and a method for producing multi-hydroxy derivatives of polyunsaturated fatty acids using the same.Type: ApplicationFiled: October 16, 2020Publication date: February 11, 2021Inventors: Jeong Woo SEO, Jong Jae YI, Sun Yeon HEO, Young Bae KIM, Chul Ho KIM, Baek Rock OH, Jung Hyun JU, Hack Sun CHOI
-
Publication number: 20190365640Abstract: Lactobacilus reuteri CH53 strain has high productivity of 1,3-propanediol from glycerol and uses thereof. It is confirmed that Lactobacilus reuteri CH53 strain is capable of converting at very high yield glycerol or crude glycerol to high-concentration 1,3-propanediol. Since Lactobacilus reuteri CH53 strain of the present invention capable of producing large amounts of 1,3-propanediol is one kind of lactic acid bacteria that are safe for humans (GRAS, Generally Recognized As Safe), when it is used for producing 1,3-propanediol from crude glycerol, it would be very advantageously used, unlike existing GMO strains, in related industries from the viewpoint of safety or environment and also providing an advantage of recycled use of resources.Type: ApplicationFiled: November 27, 2017Publication date: December 5, 2019Inventors: Chul Ho KIM, Baek Rock OH, Jeong-Woo SEO, Sun-Yeon HEO, Jung Hyun JU
-
Patent number: 9896701Abstract: The present invention relates to a method for producing 1,3-propanediol using a mutant microorganism lacking a 2,3-butanediol synthetic gene, and more particularly to a mutant microorganism wherein a gene encoding lactate dehydrogenase and a gene encoding an enzyme which is involved in 2,3-butanediol synthesis are deleted in a microorganism having the ability to produce 1,3-propanediol from glycerol and wherein a gene encoding pyruvate decarboxylase and a gene encoding aldehyde dehydrogenase are introduced or amplified, and to a method of promoting the production of 1,3-propanediol while inhibiting the production of 2,3-butanediol by using the mutant microorganism. The use of the glycerol-fermenting mutant microorganism according to the present invention can significantly increase the production of 1,3-propanediol while minimizing the production of 2,3-butanediol.Type: GrantFiled: February 16, 2015Date of Patent: February 20, 2018Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGYInventors: Chul Ho Kim, Jeong-Woo Seo, Sun-Yeon Heo, Sung Mok Lee, Jang Min Park, Baek Rock Oh, You Ree Jung
-
Publication number: 20170016032Abstract: The present invention relates to a method for producing 1,3-propanediol using a mutant microorganism lacking a 2,3-butanediol synthetic gene, and more particularly to a mutant microorganism wherein a gene encoding lactate dehydrogenase and a gene encoding an enzyme which is involved in 2,3-butanediol synthesis are deleted in a microorganism having the ability to produce 1,3-propanediol from glycerol and wherein a gene encoding pyruvate decarboxylase and a gene encoding aldehyde dehydrogenase are introduced or amplified, and to a method of promoting the production of 1,3-propanediol while inhibiting the production of 2,3-butanediol by using the mutant microorganism. The use of the glycerol-fermenting mutant microorganism according to the present invention can significantly increase the production of 1,3-propanediol while minimizing the production of 2,3-butanediol.Type: ApplicationFiled: February 16, 2015Publication date: January 19, 2017Inventors: Chul Ho Kim, Jeong-Woo Seo, Sun-Yeon Heo, Sung Mok Lee, Jang Min Park, Baek Rock Oh, You Ree Jung
-
Patent number: 9090919Abstract: The present invention relates to a novel method of producing 3-hydroxypropionic acid from glycerol, and more particularly to a method of producing 3-hydroxypropionic acid by culturing in a glycerol-containing medium a mutant microorganism obtained by amplifying an aldehyde dehydrogenase-encoding gene in a microorganism having the abilities to produce coenzyme B12 and produce 3-hydroxypropionic acid using glycerol as a carbon source. The present invention enables the fermentation of glycerol even under microaerobic or aerobic conditions without having to add coenzyme B12. Thus, the invention will be very suitable for the development of biological processes for producing large amounts of 3-hydroxypropionic acid.Type: GrantFiled: October 29, 2009Date of Patent: July 28, 2015Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGYInventors: Chul-Ho Kim, Jeong-Woo Seo, Lianhua Luo, Baek Rock Oh, Pil-Soo Seo, Sun-Yeon Heo
-
Patent number: 8951763Abstract: The present invention relates to a method for producing 3-hydroxypropionic acid by culturing in a glycerol-containing medium a mutant microorganism obtained by inserting or amplifying a gene encoding propanediol utilization protein in a microorganism having the abilities to produce coenzyme B12 and produce 3-hydroxypropionic acid using glycerol as a carbon source. According to the present invention, 3-hydroxypropionic acid can be produced in high yield from glycerol without having to add expensive coenzyme B12 as a cofactor.Type: GrantFiled: May 24, 2011Date of Patent: February 10, 2015Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Chul Ho Kim, Jeong-Woo Seo, Lianhua Luo
-
Patent number: 8617857Abstract: The present invention relates to novel thraustochytrid-like microalgae having the ability to produce bio-oil, and a method of producing bio-oil using the same. The microalgae of the invention accumulate bio-oil at a high ratio in the cells when being cultured in glucose-containing medium, and thus can produce bio-oil in a high yield. Also, the microalgae can produce bio-oil using bean powder as a nitrogen source, and a product obtained by culturing edible bean powder as medium can be used as a raw material for producing food and feed. Also, the microalgae can produce bio-oil using non-food cellulosic biomass as a carbon source. Moreover, the use of non-food cellulosic biomass for production of bio-oil can overcome the factors limiting the development of bio-oil, including the unstable supply of food resources and an increase in the cost of raw materials, and can improve the commercial competitiveness of microbial fermentation oil.Type: GrantFiled: April 25, 2011Date of Patent: December 31, 2013Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Jeong-Woo Seo, Chul Ho Kim, Dina Rairakhwada, Won Kyung Hong
-
Publication number: 20130095541Abstract: The present invention relates to a method for producing 3-hydroxypropionic acid by culturing in a glycerol-containing medium a mutant microorganism obtained by inserting or amplifying a gene encoding propanediol utilization protein in a microorganism having the abilities to produce coenzyme B12 and produce 3-hydroxypropionic acid using glycerol as a carbon source According to the present invention, 3-hydroxypropionic acid can be produced in high yield from glycerol without having to add expensive coenzyme B12 as a cofactor.Type: ApplicationFiled: May 24, 2011Publication date: April 18, 2013Applicant: Korea Research Institute of Bioscience and BiotechInventors: Chul Ho Kim, Jeong-Woo Seo, Lianhua Luo
-
Publication number: 20130089901Abstract: The present invention relates to novel thraustochytrid-like microalgae having the ability to produce bio-oil, and a method of producing bio-oil using the same. The microalgae of the invention accumulate bio-oil at a high ratio in the cells when being cultured in glucose-containing medium, and thus can produce bio-oil in a high yield. Also, the microalgae can produce bio-oil using bean powder as a nitrogen source, and a product obtained by culturing edible bean powder as medium can be used as a raw material for producing food and feed. Also, the microalgae can produce bio-oil using non-food cellulosic biomass as a carbon source. Moreover, the use of non-food cellulosic biomass for production of bio-oil can overcome the factors limiting the development of bio-oil, including the unstable supply of food resources and an increase in the cost of raw materials, and can improve the commercial competitiveness of microbial fermentation oil.Type: ApplicationFiled: April 25, 2011Publication date: April 11, 2013Applicant: Korea Research Institute of Bioscience and BiotechnologyInventors: Jeong-Woo Seo, Chul Ho Kim, Dina Rairakhwada, Won Kyung Hong
-
Patent number: 8338148Abstract: Provided is a method of producing 1,3-propanediol by culturing a recombinant strain in which the glycerol oxidative pathway had been blocked, and more particularly a method of producing 1,3-propanediol by two-step culture of a recombinant strain in which the oxidative pathway that produces byproducts in the glycerol metabolic pathway had been blocked. When the recombinant strain in which the glycerol oxidative pathway that produces byproducts had been blocked is cultured in two steps, 1,3-propanediol can be produced with improved yield without producing products that result in an increase in purification costs.Type: GrantFiled: March 12, 2009Date of Patent: December 25, 2012Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Chul-Ho Kim, Jeong-Woo Seo, Baek Rock Oh, Sun-Yeon Heo, Mi Young Seo, Min Ho Choi, Jin-Oh Baek, Pil-Soo Seo
-
Publication number: 20120270287Abstract: The present invention relates to a novel method of producing 3-hydroxypropionic acid from glycerol, and more particularly to a method of producing 3-hydroxypropionic acid by culturing in a glycerol-containing medium a mutant microorganism obtained by amplifying an aldehyde dehydrogenase-encoding gene in a microorganism having the abilities to produce coenzyme B12 and produce 3-hydroxypropionic acid using glycerol as a carbon source. The present invention enables the fermentation of glycerol even under microaerobic or aerobic conditions without having to add coenzyme B12. Thus, the invention will be very suitable for the development of biological processes for producing large amounts of 3-hydroxypropionic acid.Type: ApplicationFiled: October 29, 2009Publication date: October 25, 2012Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGYInventors: Chul-Ho Kim, Jeong-Woo Seo, Lianhua Luo, Baek Rock Oh, Pil-Soo Seo, Sun-Yeon Heo
-
Publication number: 20120045808Abstract: Provided is a method of producing 1,3-propanediol by culturing a recombinant strain in which the glycerol oxidative pathway had been blocked, and more particularly a method of producing 1,3-propanediol by two-step culture of a recombinant strain in which the oxidative pathway that produces byproducts in the glycerol metabolic pathway had been blocked. When the recombinant strain in which the glycerol oxidative pathway that produces byproducts had been blocked is cultured in two steps, 1,3-propanediol can be produced with improved yield without producing products that result in an increase in purification costs.Type: ApplicationFiled: March 12, 2009Publication date: February 23, 2012Applicant: Korea Research Institute of BiosctechnologyInventors: Chul-Ho Kim, Jeong-Woo Seo, Baek Rock Oh, Sun-Yeon Heo, Mi Young Seo, Min Ho Choi