Patents by Inventor Jesús María Hernández Rivas

Jesús María Hernández Rivas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IN VITRO DIAGNOSTIC METHOD FOR PATIENTS WITH SPLENIC MARGINAL ZONE LYMPHOMA
    Publication number: 20130267432
    Abstract: The present invention refers to an in vitro SMZL diagnostic method based on analysis of the expression of a series of genes located in a very specific deleted region of human chromosome 7. The deleted region in SMZL patients has been defined by means of high-resolution array CGH and is located at 7q22.1 between bases 99925039-101754718, preferably between 99925039-101348479, and more preferably between 100260234-100596921 and/or 101244026-101754718, which is the location for the following genes: CUX1, SH2B2, EPHB4, SLC12A9, TRIP6, SRRT, ACHE, UFSP1, TRIM56, SERPINE1, APIS1, VGF, TSC22D4, HRBL, LRCH4, MUC3, MUC12 and MUC17. The present invention further describes in vitro SMZL diagnostic kits that comprise at least one probe that recognizes the deleted region at 7q22.1 or hybridizes with at least one of the nucleotide sequences of the genes mentioned above.
    Type: Application
    Filed: June 7, 2011
    Publication date: October 10, 2013
    Applicant: FUNDACION DE INVESTIGACION DEL CANCER DE LA UNIVERSIDAD DE SALAMANCA (FICUS)
    Inventors: Jesús María Hernández Rivas, Juan Luis García Hernández, Cristina Robledo Montero