Abstract: Provided is a system for drug delivery utilizing hydrogel to deliver biologically active agents to stimulate mature intratumoral tertiary lymphoid structure formation and augment immune check point blockade. Provided herein is an injectable hydrogel that can stimulate the formation of immune structures within tumors, improving cancer prognosis and treatment response. Provided is a method of treating cancer. Also provided is a method of making the drug delivery system.

Abstract: Provided are a composition comprising a peptide conjugated to a TLR agonist, including TLR7 agonist 1v209, and methods of using the composition. The methods comprise administering the peptide-based vaccine conjugate to a subject. The peptide-based vaccine conjugate inhibits tumor growth and induces antigen-specific B and T cell responses in a subject.

Abstract: The present disclosure relates to epitope peptides for tumor-associated antigens and use thereof. The epitope peptides for tumor-associated antigens are derived from embryonic stem cells, and NUF-2. Studies have found that among embryonic stem cell-derived tumor-associated antigens selected from at least one of CENPM, IQGA3-1, IQGA3-2, KIF4A-1, KIF4A-2, and NUF-2, the tumor-associated antigens KIF4A and NUF-2 expressed by embryonic stem cells (ESCs) can effectively inhibit the growth of bladder cancer, and the tumor-associated antigens CENPM, NUF-2, and IQGA3 expressed by the ESCs can strongly stimulate the immune response of specific T cells, which is manifested by stimulating peptide-specific CTL to secrete high levels of IFN-? and inhibiting tumor growth, and the epitope peptides for tumor-associated antigens can be used in the preparation of a medicament for inhibiting the growth of tumor cells or stimulating immune cells to produce a T cell response.

Abstract: Attachment of a pluggable module to an externally-accessible slot of a base unit of a server is detected. The module is configured to execute a first network function of a radio-based communication network. In response to a determination that the module satisfies a security criterion, a second network function is launched. The second network function performs one or more computations on output of the first network function. The output of the first network function is generated at the module in response to a message from a user equipment device of a radio-based communication network.

Abstract: This invention relates to cancer immunotherapy. A method to increase antigenicity or immunogenicity of a tumor in a subject is provided. In one embodiment, said method comprises the step of delivering lipid nanoparticles loaded with mRNA sequences encoding one or more pathogen antigen proteins into said tumor.

Abstract: Attachment of a pluggable module to an externally-accessible slot of a base unit of a server is detected. The module is configured to execute a first network function of a radio-based communication network. In response to a determination that the module satisfies a security criterion, a second network function is launched. The second network function performs one or more computations on output of the first network function. The output of the first network function is generated at the module in response to a message from a user equipment device of a radio-based communication network.

Abstract: The present disclosure provides a skin beauty suction device, including: a main control board, connected to a suction pump; wherein the suction pump is connected to a suction nozzle through a gas tube, the suction nozzle being configured to be in contact with a human skin to suck blackheads; a pressure sensor is arranged between the suction pump and the suction nozzle, and the pressure sensor is electrically connected to the main control board; the main control board is electrically connected to a display. The present disclosure solves the technical problem of redness and damage to the skin due to the inability to detect and control the amount of pressure, which causes the suction device to easily apply too much force when suctioning the skin. The present disclosure has very good practical value and is easy to manufacture and use.

Abstract: Provided are an operation method and device for physiological health detection, wherein by arranging a body part identification area on a display unit, and arranging a sensing unit below the body part identification area, when a body part of a user is close to the body part identification area, the sensing unit may capture optical signal information reflected by the body part, and a processing unit may obtain, according to the optical signal information reflected by the body part, physiological health information corresponding to the body part, and the physiological health information may be displayed on the display unit. Compared with the existing method of a mobile device additionally arranging a sensor outside a display screen region, the present invention facilitates user operations and improves the user experience, and the whole thickness of the mobile device may also be effectively reduced, thereby enabling the mobile device to be lighter and thinner and satisfy the requirements of the market.

Abstract: Device and method for biometric recognition are provided. When first touch surface and second touch surface are in folded state, if it is determined that first touch surface faces current user, since sensing unit is provided under first touch surface, first touch surface can directly capture first contact information of user. When it is determined that second touch surface is facing current user, processing unit projects the touch recognition area and the second touch part that is currently in contact with first touch surface onto second touch surface correspondingly, user can move second touch part so that virtual second touch part on second touch surface is within virtual touch recognition area. Thus, touch recognition area of first touch surface which is facing away from user can obtain second contact information. Problems such as inconvenience of multi-fingerprint fingerprint operation of under-screen fingerprint recognition device after folding are solved.

Abstract: The invention relates to the field of biomedicine. In particular, the invention relates to a live strain of Staphylococcus aureus and uses thereof. More particularly, the invention relates to a live strain of Staphylococcus aureus which lacks adenosine synthase A (AdsA) activity, to a vaccine against Staphylococcus aureus infection comprising said live strain, and a method for preventing and/or treating Staphylococcus aureus infection in a subject by administering said live strain.

Abstract: The present disclosure provides a hexadeca amino- or hexadeca ammonium-modified zinc phthalocyanine and a preparation method and use thereof. In a zinc phthalocyanine structure, a 3-(dimethylamino)phenoxy substituent or a 3-(trimethylammonium) phenoxy substituent is located at peripheral positions ? and ? of a phthalocyanine ring. The zinc phthalocyanine complex has a high photosensitive activity and a high water solubility. The zinc phthalocyanine complex exists in the form of a monomer in water, which is conducive to exerting a photodynamic activity in water; meanwhile, the zinc phthalocyanine complex has an absorption spectrum red-shifted to 720 nm, which is located in a near-infrared region that is more conducive to penetrating human tissues. Therefore, the zinc phthalocyanine complex has higher tumor targeting ability and photodynamic tumor-suppression effect, and is scavenged quickly in vivo, which can be used for preparing a photosensitizer or a photodynamic drug or a photosensitive medicament.

Abstract: The present disclosure provides a module structure and an electronic apparatus. The module structure includes: a sensing component, a sensing surface and a display component disposed between the sensing component and the sensing surface; an air layer disposed between the display component and the sensing component; and a scattering layer disposed between the air layer and the display component; wherein light generated by the display component is reflected or refracted on the sensing surface to form signal light carrying an information, and the signal light is transmitted through the scattering layer and the air layer and received by the sensing component. The present disclosure can realize decoupling between the sensing component and the display component, reduce the influence of a bonding stress on a display effect of the display component, and avoid the influence of the air layer on the realization of the function of the sensing component.

Abstract: The present disclosure provides an image capturing apparatus, including: a light source module configured to emit an incident light, wherein the light source module has a first surface and a second surface opposite to each other; an LCD module having a first surface and a second surface opposite to each other, wherein the second surface of LCD module faces the first surface of light source module, an air gap is formed between LCD module and light source module, and LCD module comprises a scattering layer for scattering the incident light; a light-transmitting cover plate having a first surface and a second surface, wherein first surface of the light-transmitting cover plate is configured to contact with an object to be captured, and second surface of the light-transmitting cover plate faces first surface of LCD module; and a sensor module configured to collect incident light reflected by light-transmitting cover plate.

Abstract: Fingerprint encryption method and device, fingerprint decryption method and device, storage medium and terminal are provided. The fingerprint encryption method includes: acquiring a fingerprint image; dividing the fingerprint image into a plurality of block images according to a preset window, wherein a size of the block image is the same with a size of the preset window; determining identifiers of the plurality of block images, wherein the identifiers of the plurality of block images have a first preset order; and determining, according to the identifiers of the plurality of block images and a received encryption order, a plurality of encrypted block images to obtain an encrypted fingerprint image. Security of fingerprint storage or fingerprint transmission is enhanced.

Abstract: A biometric identification apparatus is provided to include a light-transmissible plate, a light filtering module, a display member and a photodetection member. The display member is configured to emit light, and the light is reflected by a surface of the light-transmissible plate and formed as an original reflected light. The light filtering module is configured to filter the original reflected light to obtain a light with a traveling direction in a predetermined angle range, and the photodetection member is configured to receive the light filtered by the light filtering module.

Abstract: The present disclosure provides an image sensor and electronic equipment. The image sensor includes: a pixel array, comprising a plurality of pixels, wherein a light-transmitting part is disposed between adjacent pixels; a protective layer, covering at least a part of a surface of the pixel; a conversion layer, configured to convert X-ray into visible light; wherein when X-ray is incident from a side of the image sensor, a portion of the X-ray is incident on the protective layer, another portion of X-ray transmits through the light-transmitting part between the pixels, reaches the conversion layer, and is converted into visible light by the conversion layer and received by the pixel. With the above solution, the pixels can be protected from the damage of X-ray high-energy photons while improving the resolution of the captured X-ray image.

Abstract: The present disclosure provides a fingerprint identification method and apparatus, a storage medium, and a terminal. The fingerprint identification method includes: collecting a to-be-identified fingerprint image of a to-be-identified fingerprint; identifying whether the to-be-identified fingerprint belongs to a first type of fingerprint; calculating an image correlation between the to-be-identified fingerprint image and a standard fingerprint image, when it's determined that the to-be-identified fingerprint belongs to the first type of fingerprint; calculating a feature point matching result between the to-be-identified fingerprint image and the standard fingerprint image when it's determined that the to-be-identified fingerprint does not belong to the first type of fingerprint; and determining whether the to-be-identified fingerprint is consistent with the standard fingerprint; wherein the standard fingerprint image is a fingerprint image collected from a standard fingerprint.

Abstract: A photodetection film includes at least one lower photodiode and upper photodiode layered members. The at least one lower photodiode layered member includes lower first-type, intrinsic and second-type semiconductor layers. The at least one upper photodiode layered member is disposed on the at least one lower photodiode layered member and includes upper first-type, intrinsic and second-type semiconductor layers. The upper intrinsic semiconductor layer has an amorphous silicon structure. The lower intrinsic semiconductor layer has a structure selected from one of a microcrystalline silicon structure, a microcrystalline silicon-germanium structure, and a non-crystalline silicon-germanium structure.

Abstract: The present disclosure provides a non-peripheral quaternary ammonium-modified zinc phthalocyanine and a preparation method and use thereof, belonging to the field of preparation of photodynamic drugs or photosensitizers. The non-peripheral quaternary ammonium-modified zinc phthalocyanine can be used as a photosensitizer for a photodynamic therapy (PDT) and photodynamic diagnosis, and can also be used for a photodynamic-immune synergistic therapy. Due to a unique structure, the non-peripheral quaternary ammonium-modified zinc phthalocyanine can be combined with an immune checkpoint blocker to achieve an excellent synergistic anti-tumor effect, which has a significant prospect for use in treating a metastatic tumor.

Abstract: An image capturing apparatus and method, a storage medium, and an electronic equipment are provided. The image capturing apparatus includes: a nonopaque cover plate having a first surface and a second surface opposite to each other in a thickness direction of the nonopaque cover plate, wherein the first surface of the nonopaque cover plate is opposite to an object to be captured; a light source module having a first surface and a second surface opposite to each other in a thickness direction of the light source module, wherein the first surface of the light source module is opposite to the second surface of the nonopaque cover plate; and a sensor module disposed on the second surface of the light source module.