Abstract: A method and system for automatically generating unit test cases for a computer program that can reproduce runtime problems. The method comprises: modifying the computer program according to one or more interested target program units in the program and possibly occurring run time problems; test executing the modified program; and automatically generating unit test cases according to the interested runtime problems occurring during the execution of the interested target program units. Wherein the modifying step adds captor code and problem detective code into the program, the captor code being configured to record the execution paths and execution contexts of the interested target program units in the program; and the problem detective code being configured to detect the interested unexpected exceptions possibly raised and the interested violations of predefined behavior rules possibly produced by the execution of the program units.

Abstract: New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.

Abstract: A method and apparatus for capturing graphic user interface resource of an application, which method comprises: loading resource files in which visible text data in graphic user interfaces of the application are stored; duplicating the resource files; adding identification information to each visible text data unit in the resource files, the identification information being used to uniquely identify each visible text data unit in each of the resource files; capturing at least one panel of graphic user interface according to the graphic user interfaces of the application; and saving the duplicated resource files and the at least one captured panel as the graphic user interface resource of the application into an intermediate file.

Abstract: An M.times.N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.

Abstract: An M.times.N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.

Abstract: An apparatus and a method for conducting high-throughput micro-volume dialysis-based experiments are disclosed. The apparatus includes a microfluidic base plate comprising one or more through-holes, each of the one or more through-holes being interconnected through a microfluidic channel. Each through-hole is covered by a dialysis membrane. Further, the two ends of the microfluidic channel are connected to a sample inlet port and a sample outlet port respectively. The apparatus further includes a microtiter plate comprising multiple wells. The microtiter plate is attached to the microfluidic base plate in such a way that at least one well overlies at least one through-hole, with the dialysis membrane in between. The method for conducting the high-throughput micro-volume dialysis-based experiments comprises adding reagents into the wells overlying the through-holes, and loading micro-volume samples into the through-holes.

Abstract: An M.times.N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.

Abstract: An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.

Abstract: The present invention provides a method and apparatus for capturing graphic user interface resource of an application, which method comprises: loading resource files in which visible text data in graphic user interfaces of the application are stored; duplicating the resource files; adding identification information to each visible text data unit in the resource files, the identification information being used to uniquely identify each visible text data unit in each of the resource files; capturing at least one panel of graphic user interface according to the graphic user interfaces of the application; and saving the duplicated resource files and the at least one captured panel as the graphic user interface resource of the application into an intermediate file.

Abstract: An M.times.N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.

Abstract: New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.

Abstract: A method and system for automatically generating unit test cases for a computer program that can reproduce runtime problems. The method comprises: modifying the computer program according to one or more interested target program units in the program and possibly occurring run time problems; test executing the modified program; and automatically generating unit test cases according to the interested runtime problems occurring during the execution of the interested target program units. Wherein the modifying step adds captor code and problem detective code into the program, the captor code being configured to record the execution paths and execution contexts of the interested target program units in the program; and the problem detective code being configured to detect the interested unexpected exceptions possibly raised and the interested violations of predefined behavior rules possibly produced by the execution of the program units.

Abstract: A circuit and a method for eliminating interference introduced from an image channel into a desired channel is described. The circuit includes a splitter and an adder. The splitter generates signals split from a received signal having frequency components within the desired and image channel. The adder adds together the signals output from the splitter. The circuit can be used in an TV tuner.

Abstract: The present invention is directed to a surface modified polymer comprising a surface which is covalently bonded to a surface modifying compound. Formation of the covalent bond between the polymer and the surface modifying compound is achieved by a reaction between an intrinsic functional group that is present in the polymer and the functional group of the surface modifying compound. By using a polymer having an intrinsic functional group, a separate surface activation step is avoided.

Abstract: A process for merging and using the Mediation Device Protocol with a network layer protocol. Under the merged protocol, each device joining a network enters into two stages: the Set-Up Stage and the Normal Operational Stage. During the Set-Up Stage, the device identifies its neighbors, builds a neighborhood list, obtains a Logical ID, and picks a parent node in the network. After the Set-Up Stage is complete, the device enters the Normal Operational Stage where it will send/receive control and data messages, invite and help new nodes to join the network, recover from broken links or topology changes, and other normal network operations.

Abstract: Embodiments of the invention provide devices, methods and systems for performing microfluidic chromatography. Particular embodiments provide microfluidic chromatography column devices which can perform chemical separation using small sample volumes and low pressure differentials across the column. One embodiment provides a microfluidic chromatography column device comprising a first, second and third capillary tube. A chromatographic packing is disposed in the second tube with a first and second support layer disposed on opposite ends of the second tube. The support layers are disposed in a substantially flat orientation within the tube. An external coupling joins the tubes such that the tubes are fluidically sealed. The device is configured to have a fluidic resistance such that a pressure differential across the column of less than about 10 psi produces a flow rate through the device of at least about 0.5 ml/min for a liquid solution.

Abstract: The present invention is directed to a microfluidic chromatography apparatus comprising a microfabricated fluid delivery system and a chromatography column which is in fluid communication with the fluid delivery system, and a method for producing and using the same. Preferably, the chromatography column comprises an OTLC, PCLC, or combinations thereof.

Abstract: The present invention is directed to a surface modified polymer comprising a surface which is covalently bonded to a surface modifying compound. Formation of the covalent bond between the polymer and the surface modifying compound is achieved by a reaction between an intrinsic functional group that is present in the polymer and the functional group of the surface modifying compound. By using a polymer having an intrinsic functional group, a separate surface activation step is avoided.

Abstract: The present invention is directed to a surface modified polymer comprising a surface which is covalently bonded to a surface modifying compound. Formation of the covalent bond between the polymer and the surface modifying compound is achieved by a reaction between an intrinsic functional group that is present in the polymer and the functional group of the surface modifying compound. By using a polymer having an intrinsic functional group, a separate surface activation step is avoided.

Abstract: An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.