Patents by Inventor Jiangao Song

Jiangao Song has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CB-0406 tromethamine salt
    Publication number: 20210355065
    Abstract: CB-0406 tromethamine salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
    Type: Application
    Filed: May 12, 2021
    Publication date: November 18, 2021
    Applicants: CymaBay Therapeutics, Inc., DiaTex, Inc.
    Inventors: Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
  • CB-0406 choline salt
    Publication number: 20210355066
    Abstract: CB-0406 choline salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
    Type: Application
    Filed: May 12, 2021
    Publication date: November 18, 2021
    Applicants: CymaBay Therapeutics, Inc., DiaTex, Inc.
    Inventors: Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
  • Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
    Patent number: 9925189
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: March 27, 2018
    Assignee: CYMABAY THERAPEUTICS, INC.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS
    Publication number: 20180021335
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: July 26, 2017
    Publication date: January 25, 2018
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
    Patent number: 9737537
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: August 22, 2017
    Assignee: CYMABAY THERAPEUTICS, INC.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS
    Publication number: 20170105993
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: October 25, 2016
    Publication date: April 20, 2017
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Bicyclic agonists of GPR131 and uses thereof
    Patent number: 9593109
    Abstract: The present disclosure relates to compounds that act as agonists of, or otherwise modulate the activity of, GPR131 and to their use in the treatment of various diseases. In particular embodiments, the structure of the compounds is given by Formula I: wherein the variables are as described herein. Related compositions, formulations and methods for the preparation of compounds of formula I are also described.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: March 14, 2017
    Assignee: CYMABAY THERAPEUTICS, INC.
    Inventors: Jiangao Song, Phuongly Pham, Jingyuan Ma, Aaron Robert Novack, Imad Nashashibi, David W. G. Wone, Dong-Fang Shi, Xin Chen
  • Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
    Patent number: 9150567
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: October 6, 2015
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS
    Publication number: 20150239881
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: February 19, 2015
    Publication date: August 27, 2015
    Applicant: CymaBay Therapeutics, Inc.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS
    Publication number: 20150197518
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 16, 2015
    Applicant: CYMABAY THERAPEUTICS, INC.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
    Patent number: 8975258
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: March 10, 2015
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
    Patent number: 8921350
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: December 30, 2014
    Assignee: CymaBay Therapeutics, Inc.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • DCC mediated coupling for halofenate manufacture
    Patent number: 8912356
    Abstract: The present application discloses a process for the preparation of a halofenate compound of the formula (III) or a salt thereof: wherein R, X and X? are as defined herein, the process comprising contacting a compound of formula (Ia) with a compound of formula (Ib) and N,N?-dicyclohexylcarbodiimide under conditions sufficient to form the compound of formula (III).
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: December 16, 2014
    Assignee: Cymabay Therapeutics, Inc.
    Inventor: Jiangao Song
  • N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
    Patent number: 8846675
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: September 30, 2014
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Jingyuan Ma, Christopher J. Rabbat, Jiangao Song, Xin Chen, Imad Nashashibi, Zuchun Zhao, Aaron Novack, Dong Fang Shi, Peng Cheng, Yan Zhu, Alison Murphy
  • Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
    Patent number: 8815886
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: August 26, 2014
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • GPR120 RECEPTOR AGONISTS AND USES THEREOF
    Publication number: 20140121246
    Abstract: GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
    Type: Application
    Filed: October 15, 2013
    Publication date: May 1, 2014
    Applicant: Metabolex, Inc.
    Inventors: Dong Fang Shi, Jiangao Song, Christopher J. Rabbat, Jingyuan Ma, Aaron Novack, Imad Nashashibi, Xin Chen
  • Agonists of GPR131 and uses thereof
    Patent number: 8703776
    Abstract: Chemical compounds which act as agonists of, or otherwise modulate the activity of, GPR131 are disclosed. Related compositions, formulations and methods of use are also described.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: April 22, 2014
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Aaron Robert Novack, Dong-Fang Shi, Jingyuan Ma, Imad Nashashibi, Phuongly Pham, Jiangao Song, David W. G. Wone, Xueyan Wang, Jeffrey D. Johnson, Brian Edward Lavan, Charles A. McWherter, Xin Chen
  • SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS
    Publication number: 20140038971
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Application
    Filed: March 28, 2013
    Publication date: February 6, 2014
    Applicant: Metabolex, Inc.
    Inventors: Jiangao SONG, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • GPR120 receptor agonists and uses thereof
    Patent number: 8598374
    Abstract: GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: December 3, 2013
    Assignee: Metabolex, Inc.
    Inventors: Dong Fang Shi, Jiangao Song, Christopher J. Rabbat, Jingyuan Ma, Aaron Novack, Imad Fayek Nashashibi, Xin Chen, Phuongly Pham
  • HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS
    Publication number: 20130281691
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: January 16, 2013
    Publication date: October 24, 2013
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao