Patents by Inventor Jianmin Fang

Jianmin Fang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090155959
    Abstract: A method of manufacturing a semiconductor device includes providing a substrate with an insulation layer disposed on a top surface of the substrate, forming a passive device over the top surface of the substrate, removing the substrate, depositing an insulating polymer film layer over the insulation layer, and depositing a metal layer over the insulating polymer film layer. A solder mask can be formed over the metal layer. A conformal metal layer can then be formed over the solder mask. A notch can be formed in the insulation layer to enhance the connection between the insulating polymer film layer and the insulation layer. Additional semiconductor die can be electrically connected to the passive device. The substrate is removed by removing a first amount of the substrate using a back grind process, and then removing a second amount of the substrate using a wet dry, dry etch, or chemical-mechanical planarization process.
    Type: Application
    Filed: December 18, 2007
    Publication date: June 18, 2009
    Applicant: STATS CHIPPAC, LTD.
    Inventors: Yaojian Lin, Haijing Cao, Qing Zhang, Kang Chen, Jianmin Fang
  • Publication number: 20090140381
    Abstract: A semiconductor wafer contains a substrate having a plurality of active devices formed thereon. An analog circuit is formed on the substrate. The analog circuit can be an inductor, metal-insulator-metal capacitor, or resistor. The inductor is made with copper. A through substrate via (TSV) is formed in the substrate. A conductive material is deposited in the TSV in electrical contact with the analog circuit. An under bump metallization layer is formed on a backside of the substrate in electrical contact with the TSV. A solder material is deposited on the UBM layer. The solder material is reflowed to form a solder bump. A wire bond is formed on a top surface of the substrate. A redistribution layer is formed between the TSV and UBM. The analog circuit electrically connects through the TSV to the solder bump on the back side of the substrate.
    Type: Application
    Filed: November 29, 2007
    Publication date: June 4, 2009
    Applicant: STATS CHIPPAC, LTD.
    Inventors: Yaojian Lin, Haijing Cao, Qing Zhang Zhang, Kang Chen, Jianmin Fang
  • Publication number: 20090140421
    Abstract: A semiconductor device has integrated passive circuit elements. A first substrate is formed on a backside of the semiconductor device. The passive circuit element is formed over the insulating layer. The passive circuit element can be an inductor, capacitor, or resistor. A passivation layer is formed over the passive circuit element. A carrier is attached to the passivation layer. The first substrate is removed. A non-silicon substrate is formed over the insulating layer on the backside of the semiconductor device. The non-silicon substrate is made with glass, molding compound, epoxy, polymer, or polymer composite. An adhesive layer is formed between the non-silicon substrate and insulating layer. A via is formed between the insulating layer and first passivation layer. The carrier is removed. An under bump metallization is formed over the passivation layer in electrical contact with the passive circuit element. A solder bump is formed on the under bump metallization.
    Type: Application
    Filed: December 3, 2007
    Publication date: June 4, 2009
    Applicant: STATS CHIPPAC, LTD.
    Inventors: Yaojian Lin, Haijing Cao, Qing Zhang, Kang Chen, Jianmin Fang
  • Patent number: 7498024
    Abstract: Single vector constructs for expression of an immunoglobulin molecule or fragment thereof and methods of making and using the same are described. The vectors comprise a self-processing cleavage sequence between a first and second immunoglobulin coding sequence allowing for expression of a functional antibody molecule using a single promoter. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from an expressed immunoglobulin molecule or fragment thereof. The vector constructs find utility in methods for enhanced production of biologically active immunoglobulins or fragments thereof in vitro or in vivo.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: March 3, 2009
    Assignee: Cell Genesys, Inc.
    Inventors: Jianmin Fang, Karin Jooss, Jing-Jing Qian
  • Patent number: 7485291
    Abstract: Single vector constructs for expression of a functional antibody molecule are described. The vectors have a self-processing cleavage site between two heterologous DNA coding sequences allowing for expression of two coding sequences using a single promoter. Exemplary vector constructs comprise a foot and mouth disease virus (FMDV) 2A sequence. The vector constructs can be used in methods relating to antibody delivery and therapy and in the production of a biologically active antibody or fragment thereof.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: February 3, 2009
    Assignee: Cell Genesys, Inc.
    Inventors: Jianmin Fang, Karin Jooss, Jing-Jing Qian
  • Publication number: 20080280356
    Abstract: Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.
    Type: Application
    Filed: October 26, 2007
    Publication date: November 13, 2008
    Applicant: Cell Genesys, Inc.
    Inventors: Jianmin Fang, Karin Jooss, Andrew Simmons, Jing-Jing Qian
  • Publication number: 20070292922
    Abstract: Single AAV vector constructs for regulated expression of an immunoglobulin molecule or fragment thereof and methods of making and using the same are described. The AAV vectors comprise a regulated promoter operably linked to the coding sequence for a first and second immunoglobulin coding sequence, a sequence encoding a self-processing cleavage site between the coding sequence for the first and second immunoglobulin coding sequence and a additional proteolytic cleavage site, which provides a means to remove the self processing peptide sequence from an expressed immunoglobulin molecule or fragment thereof. The vector constructs find utility in enhanced production of biologically active immunoglobulins or fragments thereof in vitro and in vivo.
    Type: Application
    Filed: March 28, 2007
    Publication date: December 20, 2007
    Applicants: Cell Genesys, Inc., ARIAD Pharmaceuticals, Inc.
    Inventors: Jianmin Fang, Karin Jooss, Minh Nguyen, Thomas Harding, Timothy Clackson, Victor Rivera
  • Publication number: 20070059820
    Abstract: Lentivector constructs for expression of recombinant proteins, polypeptides or fragments thereof and methods of making the same are described. The lentivectors typically have a self-processing cleavage sequence between a first and second protein or polypeptide coding sequence allowing for expression of a functional protein or polypeptide under operative control of a single promoter and may further include an additional proteolytic cleavage sequence which provides a means to remove the self-processing cleavage sequence from the expressed protein or polypeptide. The vector constructs find utility in methods relating to enhanced production of biologically active proteins, such as immunoglobulins or fragments thereof in vitro and in vivo.
    Type: Application
    Filed: July 18, 2006
    Publication date: March 15, 2007
    Inventors: Jianmin Fang, Karin Jooss, Andrew Simmons, Debbie Farson
  • Publication number: 20060034805
    Abstract: Single AAV vector constructs for expression of an immunoglobulin molecule or fragment thereof and methods of making and using the same are described. The AAV vectors comprise a self-processing cleavage sequence between a first and second immunoglobulin coding sequence allowing for expression of a functional antibody molecule using a single promoter. The vector constructs may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from an expressed immunoglobulin molecule or fragment thereof. The vector constructs find utility in enhanced production of biologically active immunoglobulins or fragments thereof in vitro and in vivo.
    Type: Application
    Filed: July 13, 2005
    Publication date: February 16, 2006
    Inventors: Jianmin Fang, Karin Jooss
  • Publication number: 20050136035
    Abstract: Cell specific replication-competent viral vectors comprising a self processing peptide cleavage sequence are provided. The targeted replication-competent viral vectors include two or more co-transcribed genes under transcriptional control of the same heterologous transcriptional regulatory element (TRE), wherein at least a second gene is under translational control of a self processing cleavage sequence or 2A sequence. Exemplary vector constructs may further include an additional proteolytic cleavage site which provides a means to remove the self processing peptide sequence from the viral vector.
    Type: Application
    Filed: June 1, 2004
    Publication date: June 23, 2005
    Inventors: Derek Ko, Yuanhao Li, Thomas Harding, Jianmin Fang, Nagarajan Ramesh, De Yu
  • Publication number: 20050042721
    Abstract: Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.
    Type: Application
    Filed: April 26, 2004
    Publication date: February 24, 2005
    Inventors: Jianmin Fang, Karin Jooss, Andrew Simmons, Jing-Jing Qian
  • Publication number: 20050003482
    Abstract: Single vector constructs for expression of an immunoglobulin molecule or fragment thereof and methods of making and using the same are described. The vectors comprise a self-processing cleavage sequence between a first and second immunoglobulin coding sequence allowing for expression of a functional antibody molecule using a single promoter. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from an expressed immunoglobulin molecule or fragment thereof. The vector constructs find utility in methods for enhanced production of biologically active immunoglobulins or fragments thereof in vitro or in vivo.
    Type: Application
    Filed: April 26, 2004
    Publication date: January 6, 2005
    Inventors: Jianmin Fang, Karin Jooss, Jing-Jing Qian
  • Publication number: 20040265955
    Abstract: Single vector constructs for expression of a functional antibody molecule are described. The vectors have a self-processing cleavage site between two heterologous DNA coding sequences allowing for expression of two coding sequences using a single promoter. Exemplary vector constructs comprise a foot and mouth disease virus (FMDV) 2A sequence. The vector constructs can be used in methods relating to antibody delivery and therapy and in the production of a biologically active antibody or fragment thereof.
    Type: Application
    Filed: June 3, 2003
    Publication date: December 30, 2004
    Inventors: Jianmin Fang, Karin Jooss, Jing-Jing Qian