Abstract: A display substrate and a display device are provided. The display substrate includes a plurality of pads, an insulating layer and an inorganic layer located in a peripheral region. At least one of the pads includes a first conductor portion, a second conductor portion and a third conductor portion. The third conductor portion is located on a side of the second conductor portion away from abase substrate and electrically connected to the second conductor portion. The third conductor portion is electrically connected to the second conductor portion through a second via hole disposed in the inorganic layer of the peripheral region. A projection of the first conductor portion on the base substrate is located within a projection of the second via hole on the base substrate.

Abstract: The invention relates to a fiber-optic wave guide sensor of aptamers having functions of in situ target enrichment and purification, and a method for detection of small molecules to realize the quantitative detection of small molecules targets based on that small molecules targets and the aptamers complementary short strand DNA competitively bind with aptamers tethered on the fiber surface. It synchronously realized specifically binding aptamers with targets and in situ target enrichment and purification of targets by modifying aptamers and solid micro extraction layer with silica fibers of the fiber-optic wave guide sensor, which can achieve the ultrasensitive and ultrahigh specific quick detection for all types of small molecule targets regardless of any signal amplification reaction based on enzyme. The detection limitation is very low with good generalizability.