Patents by Inventor Jielian LU

Jielian LU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMANIZED ANTI-TRKA ANTIBODIES AND USES THEREOF
    Publication number: 20230357411
    Abstract: A humanized antibody or antigen-binding fragment thereof capable of specifically recognizing TrkA and uses thereof. The antibody includes a heavy chain variable region with an amino acid sequence shown in any one of SEQ ID NO: 2-8, and a light chain variable region with an amino acid sequence shown in any one of SEQ ID NO: 10-13. The above-mentioned antibody according to the embodiments of the present invention can specifically target and bind to the TrkA receptor and block the binding of NGF and TrkA.
    Type: Application
    Filed: November 18, 2021
    Publication date: November 9, 2023
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zhiheng REN, Junji DONG, Zhuandi HE, Kezhu WANG, Jielian LU, Shushan LIN, Liang LIU, Xiang LI, Kuo ZHANG, Yan JIANG, Xiaoping LI, Xiaofeng CHEN, Wenjia LI
  • ANTI-TRKA ANTIBODIES AND USES THEREOF
    Publication number: 20220204630
    Abstract: An antibody or an antigen-binding fragment thereof is capable of specifically recognizing TrkA and uses thereof. The antibody contains a CDR sequence selected from at least one of the following or an amino acid sequence having at least 95% identity with it: heavy chain variable region CDR sequences: SEQ ID NO: 1˜27, light chain variable region CDR sequences: SEQ IN NO: 28˜54. The above antibody can specifically targeted-bind to the TrkA receptor and block the binding of NGF to TrkA.
    Type: Application
    Filed: May 28, 2020
    Publication date: June 30, 2022
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Chao CHEN, Zhiheng REN, Zhuandi HE, Jielian LU, Shushan LIN, Tingting YU, Xiling WEI, Xufang WANG, Le XU, Junji DONG, Xiang LI, Kuo ZHANG, Xueyao YANG, Linfeng GUO, Xiaoping LI, Xiaofeng CHEN, Wenjia LI